ID

14853

Beschreibung

Pregnenolone Sulfate an Early Marker of the Memory Loss in Alzheimer's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00912886

Link

https://clinicaltrials.gov/show/NCT00912886

Stichworte

  1. 01.05.16 01.05.16 -
Hochgeladen am

1. Mai 2016

DOI

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Lizenz

Creative Commons BY 4.0

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Eligibility Alzheimer Disease NCT00912886

Eligibility Alzheimer Disease NCT00912886

Inclusion Criteria
Beschreibung

Inclusion Criteria

Alias
UMLS CUI
C1512693
subjects aged over 70 years who have signed informed consent for participation to the study and are affiliated to a social security regimen.
Beschreibung

age; informed consent

Datentyp

boolean

Alias
UMLS CUI [1]
C0001779
UMLS CUI [2]
C0021430
for patients: subjects with probable ad according to the dsm-iv criteria and the nincds/adrda criteria and with mild to moderate probable ad: mmse score> 15.
Beschreibung

dsm-iv; nincds/adrda criteria; mmse score

Datentyp

boolean

Alias
UMLS CUI [1]
C0220952
UMLS CUI [2]
C2828081
UMLS CUI [3]
C2225229
for controls: subjects without cognitive deficits on neuropsychological tests: scores of mmse > 26 and of the 5 word test equal to 10/10 and of the clock drawing test equal to 7/7.
Beschreibung

cognitive deficits; mmse score

Datentyp

boolean

Alias
UMLS CUI [1]
C0009241
UMLS CUI [2]
C2225229
Exclusion Criteria
Beschreibung

Exclusion Criteria

Alias
UMLS CUI
C0680251
guardianship
Beschreibung

guardianship

Datentyp

boolean

Alias
UMLS CUI [1]
C0870627
history of cerebrovascular disease, parkinson's disease, other known dementia, epilepsy
Beschreibung

cerebrovascular disease; parkinsons disease; dementia; epilepsy

Datentyp

boolean

Alias
UMLS CUI [1]
C0007820
UMLS CUI [2]
C0030567
UMLS CUI [3]
C0497327
UMLS CUI [4]
C0014544
major depression
Beschreibung

major depression

Datentyp

boolean

Alias
UMLS CUI [1]
C1269683
serious sensory disorders; deficits in language & comprehension
Beschreibung

sensory disorders; deficits in language

Datentyp

boolean

Alias
UMLS CUI [1]
C0152027
UMLS CUI [2]
C1866856
serious heart or hepatic insufficiencies, renal or respiratory failures
Beschreibung

heart insufficiency; hepatic insufficiency; renal failure; respiratory failures

Datentyp

boolean

Alias
UMLS CUI [1]
C0018801
UMLS CUI [2]
C1306571
UMLS CUI [3]
C0035078
UMLS CUI [4]
C0852895
unstable diabetes or endocrine disorders, thyroid dysfunction, cancer, inflammatory syndrome, malnutrition
Beschreibung

diabetes; endocrine disorders; thyroid dysfunction; cancer; inflammatory syndrome; malnutrition

Datentyp

boolean

Alias
UMLS CUI [1]
C0011847
UMLS CUI [2]
C0014130
UMLS CUI [3]
C0348024
UMLS CUI [4]
C0006826
UMLS CUI [5]
C0242966
UMLS CUI [6]
C0162429
cognitive training during the 6 previous months
Beschreibung

cognitive training

Datentyp

boolean

Alias
UMLS CUI [1]
C1868940
medications: steroids (hrt, androgens, corticoids), anti-depressants, cholinesterase inhibitors, thyroid hormones, synthetic anti-thyroids
Beschreibung

steroids; anti-depressants; cholinesterase inhibitors; thyroid hormones

Datentyp

boolean

Alias
UMLS CUI [1]
C0038317
UMLS CUI [2]
C0003290
UMLS CUI [3]
C0008425
UMLS CUI [4]
C0040135
contraindications for mri: metallic implants & claustrophobia
Beschreibung

contraindication mri; claustrophobia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1301624
UMLS CUI [1,2]
C0024485
UMLS CUI [2]
C0008909

Ähnliche Modelle

Eligibility Alzheimer Disease NCT00912886

Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
C1512693 (UMLS CUI)
age; informed consent
Item
subjects aged over 70 years who have signed informed consent for participation to the study and are affiliated to a social security regimen.
boolean
C0001779 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
dsm-iv; nincds/adrda criteria; mmse score
Item
for patients: subjects with probable ad according to the dsm-iv criteria and the nincds/adrda criteria and with mild to moderate probable ad: mmse score> 15.
boolean
C0220952 (UMLS CUI [1])
C2828081 (UMLS CUI [2])
C2225229 (UMLS CUI [3])
cognitive deficits; mmse score
Item
for controls: subjects without cognitive deficits on neuropsychological tests: scores of mmse > 26 and of the 5 word test equal to 10/10 and of the clock drawing test equal to 7/7.
boolean
C0009241 (UMLS CUI [1])
C2225229 (UMLS CUI [2])
Item Group
C0680251 (UMLS CUI)
guardianship
Item
guardianship
boolean
C0870627 (UMLS CUI [1])
cerebrovascular disease; parkinsons disease; dementia; epilepsy
Item
history of cerebrovascular disease, parkinson's disease, other known dementia, epilepsy
boolean
C0007820 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0497327 (UMLS CUI [3])
C0014544 (UMLS CUI [4])
major depression
Item
major depression
boolean
C1269683 (UMLS CUI [1])
sensory disorders; deficits in language
Item
serious sensory disorders; deficits in language & comprehension
boolean
C0152027 (UMLS CUI [1])
C1866856 (UMLS CUI [2])
heart insufficiency; hepatic insufficiency; renal failure; respiratory failures
Item
serious heart or hepatic insufficiencies, renal or respiratory failures
boolean
C0018801 (UMLS CUI [1])
C1306571 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
C0852895 (UMLS CUI [4])
diabetes; endocrine disorders; thyroid dysfunction; cancer; inflammatory syndrome; malnutrition
Item
unstable diabetes or endocrine disorders, thyroid dysfunction, cancer, inflammatory syndrome, malnutrition
boolean
C0011847 (UMLS CUI [1])
C0014130 (UMLS CUI [2])
C0348024 (UMLS CUI [3])
C0006826 (UMLS CUI [4])
C0242966 (UMLS CUI [5])
C0162429 (UMLS CUI [6])
cognitive training
Item
cognitive training during the 6 previous months
boolean
C1868940 (UMLS CUI [1])
steroids; anti-depressants; cholinesterase inhibitors; thyroid hormones
Item
medications: steroids (hrt, androgens, corticoids), anti-depressants, cholinesterase inhibitors, thyroid hormones, synthetic anti-thyroids
boolean
C0038317 (UMLS CUI [1])
C0003290 (UMLS CUI [2])
C0008425 (UMLS CUI [3])
C0040135 (UMLS CUI [4])
contraindication mri; claustrophobia
Item
contraindications for mri: metallic implants & claustrophobia
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0008909 (UMLS CUI [2])

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