ID

14853

Descripción

Pregnenolone Sulfate an Early Marker of the Memory Loss in Alzheimer's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00912886

Link

https://clinicaltrials.gov/show/NCT00912886

Palabras clave

Versiones (1)
  1. 1/5/16 1/5/16 -
Subido en

1 de mayo de 2016

DOI

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Licencia

Creative Commons BY 4.0
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Eligibility Alzheimer Disease NCT00912886

Inglés

Eligibility Alzheimer Disease NCT00912886

1 formularios  
Inclusion Criteria
Descripción

Inclusion Criteria

Alias
UMLS CUI
C1512693
subjects aged over 70 years who have signed informed consent for participation to the study and are affiliated to a social security regimen.
Descripción

age; informed consent

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0001779
UMLS CUI [2]
C0021430
for patients: subjects with probable ad according to the dsm-iv criteria and the nincds/adrda criteria and with mild to moderate probable ad: mmse score> 15.
Descripción

dsm-iv; nincds/adrda criteria; mmse score

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0220952
UMLS CUI [2]
C2828081
UMLS CUI [3]
C2225229
for controls: subjects without cognitive deficits on neuropsychological tests: scores of mmse > 26 and of the 5 word test equal to 10/10 and of the clock drawing test equal to 7/7.
Descripción

cognitive deficits; mmse score

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0009241
UMLS CUI [2]
C2225229
Exclusion Criteria
Descripción

Exclusion Criteria

Alias
UMLS CUI
C0680251
guardianship
Descripción

guardianship

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0870627
history of cerebrovascular disease, parkinson's disease, other known dementia, epilepsy
Descripción

cerebrovascular disease; parkinsons disease; dementia; epilepsy

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0007820
UMLS CUI [2]
C0030567
UMLS CUI [3]
C0497327
UMLS CUI [4]
C0014544
major depression
Descripción

major depression

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1269683
serious sensory disorders; deficits in language & comprehension
Descripción

sensory disorders; deficits in language

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0152027
UMLS CUI [2]
C1866856
serious heart or hepatic insufficiencies, renal or respiratory failures
Descripción

heart insufficiency; hepatic insufficiency; renal failure; respiratory failures

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0018801
UMLS CUI [2]
C1306571
UMLS CUI [3]
C0035078
UMLS CUI [4]
C0852895
unstable diabetes or endocrine disorders, thyroid dysfunction, cancer, inflammatory syndrome, malnutrition
Descripción

diabetes; endocrine disorders; thyroid dysfunction; cancer; inflammatory syndrome; malnutrition

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0011847
UMLS CUI [2]
C0014130
UMLS CUI [3]
C0348024
UMLS CUI [4]
C0006826
UMLS CUI [5]
C0242966
UMLS CUI [6]
C0162429
cognitive training during the 6 previous months
Descripción

cognitive training

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1868940
medications: steroids (hrt, androgens, corticoids), anti-depressants, cholinesterase inhibitors, thyroid hormones, synthetic anti-thyroids
Descripción

steroids; anti-depressants; cholinesterase inhibitors; thyroid hormones

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0038317
UMLS CUI [2]
C0003290
UMLS CUI [3]
C0008425
UMLS CUI [4]
C0040135
contraindications for mri: metallic implants & claustrophobia
Descripción

contraindication mri; claustrophobia

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1301624
UMLS CUI [1,2]
C0024485
UMLS CUI [2]
C0008909
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Similar models

Eligibility Alzheimer Disease NCT00912886

1 formularios
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
C1512693 (UMLS CUI)
age; informed consent
Item
subjects aged over 70 years who have signed informed consent for participation to the study and are affiliated to a social security regimen.
boolean
C0001779 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
dsm-iv; nincds/adrda criteria; mmse score
Item
for patients: subjects with probable ad according to the dsm-iv criteria and the nincds/adrda criteria and with mild to moderate probable ad: mmse score> 15.
boolean
C0220952 (UMLS CUI [1])
C2828081 (UMLS CUI [2])
C2225229 (UMLS CUI [3])
cognitive deficits; mmse score
Item
for controls: subjects without cognitive deficits on neuropsychological tests: scores of mmse > 26 and of the 5 word test equal to 10/10 and of the clock drawing test equal to 7/7.
boolean
C0009241 (UMLS CUI [1])
C2225229 (UMLS CUI [2])
Item Group
C0680251 (UMLS CUI)
guardianship
Item
guardianship
boolean
C0870627 (UMLS CUI [1])
cerebrovascular disease; parkinsons disease; dementia; epilepsy
Item
history of cerebrovascular disease, parkinson's disease, other known dementia, epilepsy
boolean
C0007820 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0497327 (UMLS CUI [3])
C0014544 (UMLS CUI [4])
major depression
Item
major depression
boolean
C1269683 (UMLS CUI [1])
sensory disorders; deficits in language
Item
serious sensory disorders; deficits in language & comprehension
boolean
C0152027 (UMLS CUI [1])
C1866856 (UMLS CUI [2])
heart insufficiency; hepatic insufficiency; renal failure; respiratory failures
Item
serious heart or hepatic insufficiencies, renal or respiratory failures
boolean
C0018801 (UMLS CUI [1])
C1306571 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
C0852895 (UMLS CUI [4])
diabetes; endocrine disorders; thyroid dysfunction; cancer; inflammatory syndrome; malnutrition
Item
unstable diabetes or endocrine disorders, thyroid dysfunction, cancer, inflammatory syndrome, malnutrition
boolean
C0011847 (UMLS CUI [1])
C0014130 (UMLS CUI [2])
C0348024 (UMLS CUI [3])
C0006826 (UMLS CUI [4])
C0242966 (UMLS CUI [5])
C0162429 (UMLS CUI [6])
cognitive training
Item
cognitive training during the 6 previous months
boolean
C1868940 (UMLS CUI [1])
steroids; anti-depressants; cholinesterase inhibitors; thyroid hormones
Item
medications: steroids (hrt, androgens, corticoids), anti-depressants, cholinesterase inhibitors, thyroid hormones, synthetic anti-thyroids
boolean
C0038317 (UMLS CUI [1])
C0003290 (UMLS CUI [2])
C0008425 (UMLS CUI [3])
C0040135 (UMLS CUI [4])
contraindication mri; claustrophobia
Item
contraindications for mri: metallic implants & claustrophobia
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0008909 (UMLS CUI [2])
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