ID

14780

Description

A Phase I, Study to Evaluate the Safety and Tolerability of Intravenous EZN-2208 in Patients With Advanced Solid Tumors or Lymphoma (EZN-2208-01); ODM derived from: https://clinicaltrials.gov/show/NCT00520637

Link

https://clinicaltrials.gov/show/NCT00520637

Keywords

  1. 4/27/16 4/27/16 -
Uploaded on

April 27, 2016

DOI

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License

Creative Commons BY 4.0

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Eligibility Advanced Solid Tumors NCT00520637

Eligibility Advanced Solid Tumors NCT00520637

Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
histologically or cytologically confirmed diagnosis of advanced and/or metastatic solid tumor or lymphoma that is refractory to standard therapy
Description

solid tumor or lymphoma

Data type

boolean

Alias
UMLS CUI [1]
C0280100
UMLS CUI [2]
C0024299
measurable or evaluable disease
Description

measurable or evaluable disease

Data type

boolean

Alias
UMLS CUI [1]
C1513041
score of 0 to 2 on the ecog performance scale
Description

ecog

Data type

boolean

Alias
UMLS CUI [1]
C1520224
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
concurrent serious medical illness
Description

medical illness

Data type

boolean

Alias
UMLS CUI [1]
C0262926
known, clinically suspected, or history of central nervous system (cns) tumor involvement
Description

central nervous system (cns) tumor involvement

Data type

boolean

Alias
UMLS CUI [1]
C0085136
active diarrhea
Description

active diarrhea

Data type

boolean

Alias
UMLS CUI [1]
C0011991
known history of coagulation disorder
Description

coagulation disorder

Data type

boolean

Alias
UMLS CUI [1]
C0005779
patients requiring cytochrome p450 3a4 (cyp3a4) enzyme inducing medications
Description

cytochrome p450 3a4

Data type

boolean

Alias
UMLS CUI [1]
C3830625
requirement for ketoconazole or other strong inhibitor of cyp3a4 enzymes
Description

ketoconazole

Data type

boolean

Alias
UMLS CUI [1]
C0022625
prior chemotherapy, immunotherapy, investigational agent, or other therapy used to treat the cancer within 4 weeks (6 weeks for prior treatment with mitomycin c or nitrosoureas) prior to the scheduled administration of ezn-2208
Description

chemotherapy, immunotherapy

Data type

boolean

Alias
UMLS CUI [1]
C0392920
UMLS CUI [2]
C0021083

Similar models

Eligibility Advanced Solid Tumors NCT00520637

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
solid tumor or lymphoma
Item
histologically or cytologically confirmed diagnosis of advanced and/or metastatic solid tumor or lymphoma that is refractory to standard therapy
boolean
C0280100 (UMLS CUI [1])
C0024299 (UMLS CUI [2])
measurable or evaluable disease
Item
measurable or evaluable disease
boolean
C1513041 (UMLS CUI [1])
ecog
Item
score of 0 to 2 on the ecog performance scale
boolean
C1520224 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
medical illness
Item
concurrent serious medical illness
boolean
C0262926 (UMLS CUI [1])
central nervous system (cns) tumor involvement
Item
known, clinically suspected, or history of central nervous system (cns) tumor involvement
boolean
C0085136 (UMLS CUI [1])
active diarrhea
Item
active diarrhea
boolean
C0011991 (UMLS CUI [1])
coagulation disorder
Item
known history of coagulation disorder
boolean
C0005779 (UMLS CUI [1])
cytochrome p450 3a4
Item
patients requiring cytochrome p450 3a4 (cyp3a4) enzyme inducing medications
boolean
C3830625 (UMLS CUI [1])
ketoconazole
Item
requirement for ketoconazole or other strong inhibitor of cyp3a4 enzymes
boolean
C0022625 (UMLS CUI [1])
chemotherapy, immunotherapy
Item
prior chemotherapy, immunotherapy, investigational agent, or other therapy used to treat the cancer within 4 weeks (6 weeks for prior treatment with mitomycin c or nitrosoureas) prior to the scheduled administration of ezn-2208
boolean
C0392920 (UMLS CUI [1])
C0021083 (UMLS CUI [2])

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