ID

14477

Descrição

P-glycoprotein Function in Brain Diseases; ODM derived from: https://clinicaltrials.gov/show/NCT00677885

Link

https://clinicaltrials.gov/show/NCT00677885

Palavras-chave

  1. 17/04/2016 17/04/2016 -
Transferido a

17 de abril de 2016

DOI

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Licença

Creative Commons BY 4.0

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Eligibility Alzheimer Disease NCT00677885

Eligibility Alzheimer Disease NCT00677885

Criteria
Descrição

Criteria

patients with the diagnosis of probable alzheimer disease, parkinson disease, or frontotemporal dementia. all patients must either meet capacity criteria to consent to research, or be able to assign a surrogate decision-maker who is able to consent to research on the subject s behalf.
Descrição

alzheimer disease; parkinson disease; frontotemporal dementia

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0002395
UMLS CUI [2]
C0030567
UMLS CUI [3]
C0338451
healthy volunteers.
Descrição

healthy volunteers

Tipo de dados

boolean

Alias
UMLS CUI [1]
C1708335
Exclusion Criteria
Descrição

Exclusion Criteria

Alias
UMLS CUI
C0680251
current psychiatric disease, substance abuse or severe systemic disease based on history and physical exam.
Descrição

psychiatric disease; substance abuse disorder; systemic disease; physical exam

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0004936
UMLS CUI [2]
C0038586
UMLS CUI [3]
C0442893
UMLS CUI [4]
C0031809
laboratory tests with clinically significant abnormalities.
Descrição

laboratory test

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0022885
subjects on blood-thinning medications, having coagulation disorders, or clinically significant abnormal blood clotting test (pt/ptt).
Descrição

anticoagulants; coagulation disorders; PT and PTT tests

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0003280
UMLS CUI [2]
C0005779
UMLS CUI [3]
C2143037
prior participation in other research protocols or clinical care in the last year such that radiation exposure, including that from this protocol, would exceed the guidelines set by the radiation safety committee (rsc).
Descrição

Study Subject Participation Status

Tipo de dados

boolean

Alias
UMLS CUI [1]
C2348568
pregnancy or breast feeding.
Descrição

pregnancy; lactating

Tipo de dados

boolean

Alias
UMLS CUI [1,1]
C0032961
UMLS CUI [1,2]
C0006147
positive result on urine screen for illicit drugs.
Descrição

Illicit Drug Testing

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0020896
subjects who cannot lie on their back for extended periods of time.
Descrição

ability

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0085732
history of neurological disease other than alzheimer disease, parkinson disease, or frontotemporal dementia.
Descrição

neurological disease; parkinson disease; frontotemporal dementia

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0027765
UMLS CUI [2]
C0030567
UMLS CUI [3]
C0338451
subjects who have a cardiac pacemaker or metal in their body.
Descrição

cardiac pacemaker

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0030163
subjects taking cyclosporine a.
Descrição

cyclosporine a

Tipo de dados

boolean

Alias
UMLS CUI [1]
C0010592

Similar models

Eligibility Alzheimer Disease NCT00677885

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de dados
Alias
Item Group
alzheimer disease; parkinson disease; frontotemporal dementia
Item
patients with the diagnosis of probable alzheimer disease, parkinson disease, or frontotemporal dementia. all patients must either meet capacity criteria to consent to research, or be able to assign a surrogate decision-maker who is able to consent to research on the subject s behalf.
boolean
C0002395 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0338451 (UMLS CUI [3])
healthy volunteers
Item
healthy volunteers.
boolean
C1708335 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
psychiatric disease; substance abuse disorder; systemic disease; physical exam
Item
current psychiatric disease, substance abuse or severe systemic disease based on history and physical exam.
boolean
C0004936 (UMLS CUI [1])
C0038586 (UMLS CUI [2])
C0442893 (UMLS CUI [3])
C0031809 (UMLS CUI [4])
laboratory test
Item
laboratory tests with clinically significant abnormalities.
boolean
C0022885 (UMLS CUI [1])
anticoagulants; coagulation disorders; PT and PTT tests
Item
subjects on blood-thinning medications, having coagulation disorders, or clinically significant abnormal blood clotting test (pt/ptt).
boolean
C0003280 (UMLS CUI [1])
C0005779 (UMLS CUI [2])
C2143037 (UMLS CUI [3])
Study Subject Participation Status
Item
prior participation in other research protocols or clinical care in the last year such that radiation exposure, including that from this protocol, would exceed the guidelines set by the radiation safety committee (rsc).
boolean
C2348568 (UMLS CUI [1])
pregnancy; lactating
Item
pregnancy or breast feeding.
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
Illicit Drug Testing
Item
positive result on urine screen for illicit drugs.
boolean
C0020896 (UMLS CUI [1])
ability
Item
subjects who cannot lie on their back for extended periods of time.
boolean
C0085732 (UMLS CUI [1])
neurological disease; parkinson disease; frontotemporal dementia
Item
history of neurological disease other than alzheimer disease, parkinson disease, or frontotemporal dementia.
boolean
C0027765 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0338451 (UMLS CUI [3])
cardiac pacemaker
Item
subjects who have a cardiac pacemaker or metal in their body.
boolean
C0030163 (UMLS CUI [1])
cyclosporine a
Item
subjects taking cyclosporine a.
boolean
C0010592 (UMLS CUI [1])

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