ID

14348

Beschreibung

FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis; ODM derived from: https://clinicaltrials.gov/show/NCT00404859

Link

https://clinicaltrials.gov/show/NCT00404859

Stichworte

  1. 11.04.16 11.04.16 -
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CC BY-NC 3.0

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11. April 2016

DOI

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Creative Commons BY-NC 3.0

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Eligibility Asthma NCT00404859

Eligibility Asthma NCT00404859

  1. StudyEvent: Eligibility
    1. Eligibility Asthma NCT00404859
Inclusion Criteria
Beschreibung

Inclusion Criteria

Alias
UMLS CUI
C1512693
asthma is defined as a chronic inflammatory disorder, leading to recurrent episodes of wheezing, breathlessness, chest tightness, and/or coughing, based on variable airway obstruction [18]. children with docter-diagnosed asthma known at the department of paediatric pulmonology, were recruited from the university hospital maastricht. atopic and not atopic asthmatic children were allowed; treatment with inhalation corticosteroïd (ics) was not obliged.
Beschreibung

asthma

Datentyp

boolean

Alias
UMLS CUI [1]
C0004096
UMLS CUI [2]
C0586793
children known with cf were recruited from university hospital maastricht. cf was defined as a combination of typical clinical features and an abnormal sweat test (chloride > 60 mm). cf lung disease was treated according to the cbo consensus ref. main aspects of treatment were:
Beschreibung

cystic fibrosis

Datentyp

boolean

Alias
UMLS CUI [1]
C0010674
antibiotic treatment,
Beschreibung

antibiotic treatment

Datentyp

boolean

Alias
UMLS CUI [1]
C0003232
agents to promote airway secretion clearance, such as dnase,
Beschreibung

agents to promote airway secretion clearance

Datentyp

boolean

Alias
UMLS CUI [1]
C3804983
bronchodilators, and,
Beschreibung

bronchodilator

Datentyp

boolean

Alias
UMLS CUI [1]
C0006280
physiotherapy. all alternations of medical therapy were allowed and accurately documented.
Beschreibung

physiotherapy

Datentyp

boolean

Alias
UMLS CUI [1]
C0949766
Exclusion Criteria
Beschreibung

Exclusion Criteria

Alias
UMLS CUI
C0680251
diseases that may interfere with the results of the study (e.g. upper airway infection, cor vitium, anatomic abnormalities of the airway and other chronic inflammatory diseases, such as morbus crohn and rheumatoid arthritis),
Beschreibung

comorbidity limiting study protocol

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1321605
UMLS CUI [1,2]
C0439801
UMLS CUI [1,3]
C0009488
mental retardation,
Beschreibung

mental retardation

Datentyp

boolean

Alias
UMLS CUI [1]
C0025362
inability to perform measurements properly,
Beschreibung

inability to perform measurements properly

Datentyp

boolean

Alias
UMLS CUI [1]
C1321605
active smoking and,
Beschreibung

active smoking

Datentyp

boolean

Alias
UMLS CUI [1]
C3241966
use of the following medication: papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors
Beschreibung

papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors

Datentyp

boolean

Alias
UMLS CUI [1]
C0030350
UMLS CUI [2]
C0037533
UMLS CUI [3]
C0003015
UMLS CUI [4]
C0030071
UMLS CUI [5]
C0003765
UMLS CUI [6]
C1373060

Ähnliche Modelle

Eligibility Asthma NCT00404859

  1. StudyEvent: Eligibility
    1. Eligibility Asthma NCT00404859
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
C1512693 (UMLS CUI)
asthma
Item
asthma is defined as a chronic inflammatory disorder, leading to recurrent episodes of wheezing, breathlessness, chest tightness, and/or coughing, based on variable airway obstruction [18]. children with docter-diagnosed asthma known at the department of paediatric pulmonology, were recruited from the university hospital maastricht. atopic and not atopic asthmatic children were allowed; treatment with inhalation corticosteroïd (ics) was not obliged.
boolean
C0004096 (UMLS CUI [1])
C0586793 (UMLS CUI [2])
cystic fibrosis
Item
children known with cf were recruited from university hospital maastricht. cf was defined as a combination of typical clinical features and an abnormal sweat test (chloride > 60 mm). cf lung disease was treated according to the cbo consensus ref. main aspects of treatment were:
boolean
C0010674 (UMLS CUI [1])
antibiotic treatment
Item
antibiotic treatment,
boolean
C0003232 (UMLS CUI [1])
agents to promote airway secretion clearance
Item
agents to promote airway secretion clearance, such as dnase,
boolean
C3804983 (UMLS CUI [1])
bronchodilator
Item
bronchodilators, and,
boolean
C0006280 (UMLS CUI [1])
physiotherapy
Item
physiotherapy. all alternations of medical therapy were allowed and accurately documented.
boolean
C0949766 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
comorbidity limiting study protocol
Item
diseases that may interfere with the results of the study (e.g. upper airway infection, cor vitium, anatomic abnormalities of the airway and other chronic inflammatory diseases, such as morbus crohn and rheumatoid arthritis),
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
mental retardation
Item
mental retardation,
boolean
C0025362 (UMLS CUI [1])
inability to perform measurements properly
Item
inability to perform measurements properly,
boolean
C1321605 (UMLS CUI [1])
active smoking
Item
active smoking and,
boolean
C3241966 (UMLS CUI [1])
papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors
Item
use of the following medication: papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors
boolean
C0030350 (UMLS CUI [1])
C0037533 (UMLS CUI [2])
C0003015 (UMLS CUI [3])
C0030071 (UMLS CUI [4])
C0003765 (UMLS CUI [5])
C1373060 (UMLS CUI [6])

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