ID

14243

Descrizione

Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00181272

collegamento

https://clinicaltrials.gov/show/NCT00181272

Keywords

  1. 05/04/16 05/04/16 -
Titolare del copyright

CC BY-NC 3.0

Caricato su

5 aprile 2016

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY-NC 3.0

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Eligibility Asthma NCT00181272

Eligibility Asthma NCT00181272

  1. StudyEvent: Eligibility
    1. Eligibility Asthma NCT00181272
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
physician-diagnosis of asthma, copd exacerbation, or undifferentiated asthma/copd exacerbation
Descrizione

asthma, copd exacerbation, or undifferentiated asthma/copd exacerbation

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0004096
UMLS CUI [2]
C0740304
admitted to the inpatient medical service at johns hopkins hospital or johns hopkins bayview medical center
Descrizione

inpatient

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0021562
evidence of airflow obstruction on spirometry (fev1/fvc<70%)
Descrizione

fev1/fvc

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0429745
age 18 years or older
Descrizione

age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
history of allergy or other contraindication to macrolides (azithromycin, erythromycin, clarithromycin)
Descrizione

allergy to macrolides

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0020517
UMLS CUI [1,2]
C0003240
treatment with any macrolide in the 4 weeks prior to study entry
Descrizione

macrolide treatment

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0003240
UMLS CUI [1,2]
C0040223
elevated ast or alt (2 or more times the upper limit of normal) on current admission
Descrizione

ast, alt

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0201899
UMLS CUI [2]
C0201836
elevated alkaline phosphatase (>1.25 times the upper limit of normal) on current admission
Descrizione

AP

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0201850
elevated total serum bilirubin (more than upper limit of normal) on current admission
Descrizione

total serum bilirubin

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1278039
previous participation in this study
Descrizione

previous participation in this study

Tipo di dati

boolean

Alias
UMLS CUI [1]
C2348568
patients prescribed digoxin (azithromycin may increase digoxin levels)
Descrizione

digoxin

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0012265
patients prescribed warfarin (azithromycin may increase inr in patients on warfarin)
Descrizione

warfarin

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0043031
patients prescribed pimozide (azithromycin may increase risk of arrhythmias)
Descrizione

pimozide

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0031935
patient unable to provide consent (e.g., language difficulty or history of dementia)
Descrizione

inability to provide consent

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0021430
patient to be discharged to a location other than home (e.g., other hospital, long-term care facility)
Descrizione

discharge

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0586514

Similar models

Eligibility Asthma NCT00181272

  1. StudyEvent: Eligibility
    1. Eligibility Asthma NCT00181272
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
asthma, copd exacerbation, or undifferentiated asthma/copd exacerbation
Item
physician-diagnosis of asthma, copd exacerbation, or undifferentiated asthma/copd exacerbation
boolean
C0004096 (UMLS CUI [1])
C0740304 (UMLS CUI [2])
inpatient
Item
admitted to the inpatient medical service at johns hopkins hospital or johns hopkins bayview medical center
boolean
C0021562 (UMLS CUI [1])
fev1/fvc
Item
evidence of airflow obstruction on spirometry (fev1/fvc<70%)
boolean
C0429745 (UMLS CUI [1])
age
Item
age 18 years or older
boolean
C0001779 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
allergy to macrolides
Item
history of allergy or other contraindication to macrolides (azithromycin, erythromycin, clarithromycin)
boolean
C0020517 (UMLS CUI [1,1])
C0003240 (UMLS CUI [1,2])
macrolide treatment
Item
treatment with any macrolide in the 4 weeks prior to study entry
boolean
C0003240 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
ast, alt
Item
elevated ast or alt (2 or more times the upper limit of normal) on current admission
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
AP
Item
elevated alkaline phosphatase (>1.25 times the upper limit of normal) on current admission
boolean
C0201850 (UMLS CUI [1])
total serum bilirubin
Item
elevated total serum bilirubin (more than upper limit of normal) on current admission
boolean
C1278039 (UMLS CUI [1])
previous participation in this study
Item
previous participation in this study
boolean
C2348568 (UMLS CUI [1])
digoxin
Item
patients prescribed digoxin (azithromycin may increase digoxin levels)
boolean
C0012265 (UMLS CUI [1])
warfarin
Item
patients prescribed warfarin (azithromycin may increase inr in patients on warfarin)
boolean
C0043031 (UMLS CUI [1])
pimozide
Item
patients prescribed pimozide (azithromycin may increase risk of arrhythmias)
boolean
C0031935 (UMLS CUI [1])
inability to provide consent
Item
patient unable to provide consent (e.g., language difficulty or history of dementia)
boolean
C0021430 (UMLS CUI [1])
discharge
Item
patient to be discharged to a location other than home (e.g., other hospital, long-term care facility)
boolean
C0586514 (UMLS CUI [1])

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