ID
13754
Description
Decitabine Maintenance in Elderly Acute Myeloid Leukemia Patients; ODM derived from: https://clinicaltrials.gov/show/NCT01149408
Lien
https://clinicaltrials.gov/show/NCT01149408
Mots-clés
Versions (1)
- 03/03/2016 03/03/2016 -
Détendeur de droits
CC BY-NC 3.0
Téléchargé le
3 mars 2016
DOI
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Licence
Creative Commons BY-NC 3.0
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Eligibility Acute Myeloid Leukemia NCT01149408
Eligibility Acute Myeloid Leukemia NCT01149408
- StudyEvent: Eligibility
Description
Exclusion Criteria
Alias
- UMLS CUI
- C0680251
Description
1. diagnosis of acute promyelocytic leukemia (apl, who classification of apl with t(15;17)(q22;q12)
Type de données
boolean
Alias
- UMLS CUI [1]
- C0023487
Description
2. prior diagnosis and treatment for aml, including hematopoietic stem cell transplant (hsct)
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C0023467
- UMLS CUI [1,2]
- C1514463
- UMLS CUI [2,1]
- C0472699
- UMLS CUI [2,2]
- C1514463
Description
3. previous therapy with a hypomethylating agent including decitabine or azacitidine (i.e. for an antecedent myelodysplastic syndrome)
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C2613367
- UMLS CUI [1,2]
- C0013227
Description
4. any prior therapy for aml except for hydroxyurea for the control of blood counts
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C0023467
- UMLS CUI [1,2]
- C1514463
- UMLS CUI [2]
- C0020402
Description
5. psychiatric disorders that would interfere with consent, study participation, or follow-up
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C1321605
- UMLS CUI [1,2]
- C0439801
- UMLS CUI [1,3]
- C0009488
Description
6. cardiac disease: heart failure nyha class 3 or 4; unstable coronary artery disease (mi more than 6 months prior to study entry is permitted); serious cardiac ventricular arrhythmias requiring anti-arrhythmic therapy (beta blockers or digoxin are permitted)
Type de données
boolean
Alias
- UMLS CUI [1]
- C1275491
- UMLS CUI [2,1]
- C0010068
- UMLS CUI [2,2]
- C0443343
- UMLS CUI [3]
- C0085612
- UMLS CUI [4]
- C1979623
- UMLS CUI [5,1]
- C0027051
- UMLS CUI [5,2]
- C0011008
- UMLS CUI [6]
- C0001645
- UMLS CUI [7]
- C0012265
Description
7. chronically impaired renal function (creatinine clearance < 30 ml / min)
Type de données
boolean
Alias
- UMLS CUI [1]
- C0373595
Description
8. inadequate liver function (alt and ast ≥ 2.5 x uln) if not caused by leukemic infiltration
Type de données
boolean
Alias
- UMLS CUI [1]
- C0201836
- UMLS CUI [2]
- C0201899
Description
9. total bilirubin ≥ 1.5 x uln if not caused by leukemic infiltration
Type de données
boolean
Alias
- UMLS CUI [1]
- C1278039
Description
10. known hiv and/or hepatitis c infection
Type de données
boolean
Alias
- UMLS CUI [1]
- C0019682
- UMLS CUI [2]
- C0019196
Description
11. evidence or history of severe non-leukemia associated bleeding diathesis or coagulopathy
Type de données
boolean
Alias
- UMLS CUI [1]
- C0005779
Description
12. evidence or recent history of cns disease, including primary or metastatic brain tumors, seizure disorders
Type de données
boolean
Alias
- UMLS CUI [1]
- C0007682
Description
13. clinical evidence suggestive of central nervous system (cns) involvement with leukemia unless a lumbar puncture confirms the absence of leukemic blasts in the cerebrospinal fluid (csf)
Type de données
boolean
Alias
- UMLS CUI [1]
- C1332884
- UMLS CUI [2,1]
- C0368761
- UMLS CUI [2,2]
- C0007806
Description
14. any other severe concurrent disease, or have a history of serious organ dysfunction or disease involving the heart, kidney, liver, or other organ system that may place the patient at undue risk to undergo therapy on this protocol
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C1321605
- UMLS CUI [1,2]
- C0439801
- UMLS CUI [1,3]
- C0009488
Description
15. systemic fungal, bacterial, viral, or other infection not controlled (defined as exhibiting ongoing signs/symptoms related to the infection and without improvement, despite appropriate antibiotics or other treatment)
Type de données
boolean
Alias
- UMLS CUI [1]
- C0009450
Description
16. diagnosis of another malignancy, unless the patient has been disease-free for at least 5 years following the completion of curative intent therapy with the following exceptions: patients with treated non-melanoma skin cancer, in situ carcinoma, or cervical intraepithelial neoplasia, regardless of the disease-free duration, are eligible for this study if definitive treatment for the condition has been completed. patients with organ-confined prostate cancer with no evidence of recurrent or progressive disease based on prostate-specific antigen (psa) values are also eligible for this study if hormonal therapy has been initiated or a radical prostatectomy has been performed
Type de données
boolean
Alias
- UMLS CUI [1]
- C0006826
- UMLS CUI [2]
- C0007099
- UMLS CUI [3]
- C0699893
- UMLS CUI [4]
- C0206708
- UMLS CUI [5]
- C0600139
Description
17. history of organ allograft
Type de données
boolean
Alias
- UMLS CUI [1]
- C0178784
Description
18. any severe concomitant condition, which makes it undesirable for the patient to participate in the study or which could jeopardize compliance with the protocol
Type de données
boolean
Alias
- UMLS CUI [1,1]
- C1321605
- UMLS CUI [1,2]
- C0439801
- UMLS CUI [1,3]
- C0009488
Description
19. patients who have an indication for and can undergo a non-myeloablative transplant procedure
Type de données
boolean
Alias
- UMLS CUI [1]
- C1831742
Similar models
Eligibility Acute Myeloid Leukemia NCT01149408
- StudyEvent: Eligibility
C1515568 (UMLS CUI [1,2])
C0677874 (UMLS CUI [1,3])
C0280449 (UMLS CUI [2,1])
C0677874 (UMLS CUI [2,2])
C0023487 (UMLS CUI [3])
C0010711 (UMLS CUI [4])
C0020789 (UMLS CUI [5])
C0677874 (UMLS CUI [2])
C0700589 (UMLS CUI [2])
C1278039 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0201836 (UMLS CUI [4])
C1514463 (UMLS CUI [1,2])
C0472699 (UMLS CUI [2,1])
C1514463 (UMLS CUI [2,2])
C0013227 (UMLS CUI [1,2])
C1514463 (UMLS CUI [1,2])
C0020402 (UMLS CUI [2])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
C0010068 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0085612 (UMLS CUI [3])
C1979623 (UMLS CUI [4])
C0027051 (UMLS CUI [5,1])
C0011008 (UMLS CUI [5,2])
C0001645 (UMLS CUI [6])
C0012265 (UMLS CUI [7])
C0201899 (UMLS CUI [2])
C0019196 (UMLS CUI [2])
C0368761 (UMLS CUI [2,1])
C0007806 (UMLS CUI [2,2])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
C0007099 (UMLS CUI [2])
C0699893 (UMLS CUI [3])
C0206708 (UMLS CUI [4])
C0600139 (UMLS CUI [5])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])