ID

13611

Beschrijving

Topotecan in Treating Children With Refractory Leukemia; ODM derived from: https://clinicaltrials.gov/show/NCT00002705

Link

https://clinicaltrials.gov/show/NCT00002705

Trefwoorden

  1. 19-02-16 19-02-16 -
Geüploaded op

19 februari 2016

DOI

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Licentie

Creative Commons BY 4.0

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Eligibility Leukemia NCT00002705

Eligibility Leukemia NCT00002705

  1. StudyEvent: Eligibility
    1. Eligibility Leukemia NCT00002705
Criteria
Beschrijving

Criteria

histologically or cytologically confirmed leukemia refractory to conventional therapy or for which no effective curative therapy exists
Beschrijving

leukemia, refractory

Datatype

boolean

Alias
UMLS CUI [1,1]
C0023418
UMLS CUI [1,2]
C0205269
age: under 21
Beschrijving

Age

Datatype

boolean

Alias
UMLS CUI [1]
C0001779
performance status: ecog 0-2
Beschrijving

performance status

Datatype

boolean

Alias
UMLS CUI [1]
C1520224
life expectancy: at least 8 weeks
Beschrijving

life expectancy

Datatype

boolean

Alias
UMLS CUI [1]
C0023671
adequate platelet count and hemoglobin required (transfusion allowed)
Beschrijving

platelet count, hemoglobin

Datatype

boolean

Alias
UMLS CUI [1]
C0005821
UMLS CUI [2]
C0019046
bilirubin no greater than 1.5 mg/dl
Beschrijving

bilirubin

Datatype

boolean

Alias
UMLS CUI [1]
C1278039
ast or alt no greater than 2 times normal
Beschrijving

ast or alt

Datatype

boolean

Alias
UMLS CUI [1,1]
C0201899
UMLS CUI [1,2]
C0201836
creatinine less than 1.5 mg/dl
Beschrijving

creatinine

Datatype

boolean

Alias
UMLS CUI [1]
C0201976
adequate nutritional status, e.g. higher than third percentile weight for height
Beschrijving

nutritional status

Datatype

boolean

Alias
UMLS CUI [1]
C0392209
albumin at least 3 g/dl
Beschrijving

albumin

Datatype

boolean

Alias
UMLS CUI [1]
C0201838
no severe uncontrolled infection
Beschrijving

no severe uncontrolled infection

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
no pregnant women
Beschrijving

pregnancy

Datatype

boolean

Alias
UMLS CUI [1]
C0549206
effective contraception required of fertile women
Beschrijving

contraception

Datatype

boolean

Alias
UMLS CUI [1]
C0700589
at least 3 weeks since systemic chemotherapy (6 weeks since nitrosoureas)
Beschrijving

chemotherapy

Datatype

boolean

Alias
UMLS CUI [1,1]
C0392920
UMLS CUI [1,2]
C0011008
recovered at least 3 months since bone marrow transplant (at least 6 months since total-body irradiation)
Beschrijving

time since bone marrow transplant, total-body irradiation

Datatype

boolean

Alias
UMLS CUI [1]
C0005961
UMLS CUI [2]
C0043162
UMLS CUI [3]
C0011008
no concurrent anticancer therapy
Beschrijving

anticancer therapy

Datatype

boolean

Alias
UMLS CUI [1]
C0920425
no concurrent treatment studies
Beschrijving

concurrent treatment studies

Datatype

boolean

Alias
UMLS CUI [1]
C2348568

Similar models

Eligibility Leukemia NCT00002705

  1. StudyEvent: Eligibility
    1. Eligibility Leukemia NCT00002705
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
leukemia, refractory
Item
histologically or cytologically confirmed leukemia refractory to conventional therapy or for which no effective curative therapy exists
boolean
C0023418 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
Age
Item
age: under 21
boolean
C0001779 (UMLS CUI [1])
performance status
Item
performance status: ecog 0-2
boolean
C1520224 (UMLS CUI [1])
life expectancy
Item
life expectancy: at least 8 weeks
boolean
C0023671 (UMLS CUI [1])
platelet count, hemoglobin
Item
adequate platelet count and hemoglobin required (transfusion allowed)
boolean
C0005821 (UMLS CUI [1])
C0019046 (UMLS CUI [2])
bilirubin
Item
bilirubin no greater than 1.5 mg/dl
boolean
C1278039 (UMLS CUI [1])
ast or alt
Item
ast or alt no greater than 2 times normal
boolean
C0201899 (UMLS CUI [1,1])
C0201836 (UMLS CUI [1,2])
creatinine
Item
creatinine less than 1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
nutritional status
Item
adequate nutritional status, e.g. higher than third percentile weight for height
boolean
C0392209 (UMLS CUI [1])
albumin
Item
albumin at least 3 g/dl
boolean
C0201838 (UMLS CUI [1])
no severe uncontrolled infection
Item
no severe uncontrolled infection
boolean
C0009488 (UMLS CUI [1])
pregnancy
Item
no pregnant women
boolean
C0549206 (UMLS CUI [1])
contraception
Item
effective contraception required of fertile women
boolean
C0700589 (UMLS CUI [1])
chemotherapy
Item
at least 3 weeks since systemic chemotherapy (6 weeks since nitrosoureas)
boolean
C0392920 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
time since bone marrow transplant, total-body irradiation
Item
recovered at least 3 months since bone marrow transplant (at least 6 months since total-body irradiation)
boolean
C0005961 (UMLS CUI [1])
C0043162 (UMLS CUI [2])
C0011008 (UMLS CUI [3])
anticancer therapy
Item
no concurrent anticancer therapy
boolean
C0920425 (UMLS CUI [1])
concurrent treatment studies
Item
no concurrent treatment studies
boolean
C2348568 (UMLS CUI [1])

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