ID
13603
Beschrijving
Study to Assess the Safety, Tolerability, and Efficacy of Tipifarnib Plus Bortezomib in the Treatment of Acute Myeloid Leukemia; ODM derived from: https://clinicaltrials.gov/show/NCT00510939
Link
https://clinicaltrials.gov/show/NCT00510939
Trefwoorden
Versies (1)
- 19-02-16 19-02-16 -
Houder van rechten
CC BY-NC 3.0
Geüploaded op
19 februari 2016
DOI
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Licentie
Creative Commons BY-NC 3.0
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Eligibility Acute Myeloid Leukemia NCT00510939
Eligibility Acute Myeloid Leukemia NCT00510939
- StudyEvent: Eligibility
Beschrijving
Exclusion Criteria
Alias
- UMLS CUI
- C0680251
Beschrijving
1. serum bilirubin 2 x> upper limit of normal (uln)
Datatype
boolean
Alias
- UMLS CUI [1]
- C1278039
Beschrijving
2. aspartate aminotransferase (ast/sgot) or alanine aminotransferase (alt/sgpt) >3.5 x uln
Datatype
boolean
Alias
- UMLS CUI [1]
- C0201836
- UMLS CUI [2]
- C0201899
Beschrijving
3. serum creatinine ³ 2.5 x uln or 24-hour creatinine clearance £ 60 ml/min (measured or calculated by cockcroft-gault)
Datatype
boolean
Alias
- UMLS CUI [1]
- C0201976
- UMLS CUI [2]
- C0373595
Beschrijving
4. patients with aml of fab m3 classification (apl)
Datatype
boolean
Alias
- UMLS CUI [1]
- C0023487
Beschrijving
5. patients with a history of another primary malignancy within the previous 1 year other than basal cell carcinoma or carcinoma in situ, the patient is in remission
Datatype
boolean
Alias
- UMLS CUI [1]
- C0006826
Beschrijving
6. any clinically defined central nervous system aml.
Datatype
boolean
Alias
- UMLS CUI [1]
- C1332884
- UMLS CUI [2]
- C0023467
Beschrijving
7. participation in an investigational drug study within the 30 days prior to entry
Datatype
boolean
Alias
- UMLS CUI [1]
- C2348568
Beschrijving
8. evidence of uncontrolled infection or cns-hemorrhagic
Datatype
boolean
Alias
- UMLS CUI [1]
- C0009488
Beschrijving
9. patients with documented cases of human immunodeficiency virus (hiv)
Datatype
boolean
Alias
- UMLS CUI [1]
- C0019682
Beschrijving
10. peripheral neuropathy or neuropathic pain grade > or = 2
Datatype
boolean
Alias
- UMLS CUI [1]
- C0031117
- UMLS CUI [2]
- C0458960
Beschrijving
11. has known or suspected hypersensitivity or intolerance to boron, mannitol, or heparin, if an indwelling catheter is used
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0020517
- UMLS CUI [1,2]
- C0006030
- UMLS CUI [2,1]
- C0020517
- UMLS CUI [2,2]
- C0024730
- UMLS CUI [3,1]
- C0020517
- UMLS CUI [3,2]
- C0019134
Beschrijving
12. uncontrolled or severe cardiovascular disease including myocardial infarction within 6 months of enrollment, new york heart association (nyha) class iii or iv heart failure (attachment 7,nyha classification of cardiac disease), uncontrolled angina, clinically significant pericardial disease, or cardiac amyloidosis
Datatype
boolean
Alias
- UMLS CUI [1]
- C0018799
Beschrijving
13. rasgrp1/aptx gene expression ratio calculated at the screening <10 (part b.2 only)
Datatype
boolean
Alias
- UMLS CUI [1]
- C1419283
- UMLS CUI [2]
- C1423885
Similar models
Eligibility Acute Myeloid Leukemia NCT00510939
- StudyEvent: Eligibility
C0023467 (UMLS CUI [2,1])
C1518321 (UMLS CUI [2,2])
C0392920 (UMLS CUI [3,1])
C3841806 (UMLS CUI [3,2])
C0035020 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
C0392920 (UMLS CUI [2])
C0232970 (UMLS CUI [2])
C1423885 (UMLS CUI [2])
C0201899 (UMLS CUI [2])
C0373595 (UMLS CUI [2])
C0023467 (UMLS CUI [2])
C0458960 (UMLS CUI [2])
C0006030 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0024730 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0019134 (UMLS CUI [3,2])
C1423885 (UMLS CUI [2])
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