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ID

12910

Descrizione

L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes; ODM derived from: https://clinicaltrials.gov/show/NCT00329498

collegamento

https://clinicaltrials.gov/show/NCT00329498

Keywords

  1. 06/01/16 06/01/16 -
Titolare del copyright

CC BY-NC 3.0

Caricato su

6 gennaio 2016

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY-NC 3.0

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    Eligibility Acute Myeloid Leukemia NCT00329498

    Eligibility Acute Myeloid Leukemia NCT00329498

    Inclusion Criteria
    Descrizione

    Inclusion Criteria

    Alias
    UMLS CUI
    C1512693 (Inclusion)
    patients should have aml or mds according to new who classification, with minimum of 5% blasts in peripheral blood.
    Descrizione

    AML or MDS

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0023467 (Leukemia, Myelocytic, Acute)
    SNOMED
    17788007
    UMLS CUI [2]
    C3463824 (MYELODYSPLASTIC SYNDROME)
    SNOMED
    109995007
    there must be a clear and acceptable reason for not receiving standard treatments (chemotherapy and/or stem cell transplantation); or standard treatments have already been given and this option exhausted with evidence of refractory disease.
    Descrizione

    Treatment history

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0087111 (Therapeutic procedure)
    SNOMED
    277132007
    LOINC
    LP21090-3
    prior treatments of any forms are allowed provided there is no potential residual beneficial effect and the patients are off treatment for at least 4 weeks, with estimated life expectancy of at least 2 months.
    Descrizione

    Prior treatment

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0087111 (Therapeutic procedure)
    SNOMED
    277132007
    LOINC
    LP21090-3
    adequate amount (4 ml) of bone marrow sent to the laboratory for cell culture studies.
    Descrizione

    Bone marrow

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0005953 (Bone Marrow)
    SNOMED
    279729006
    LOINC
    LP7410-6
    there are no restrictions based on age, sex, or ethnicity except that adequate contraception must be practiced in women of childbearing ages. although aml is rare in children, pediatric patients will be accepted.
    Descrizione

    Further restrictions

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0700589 (Contraceptive methods)
    SNOMED
    13197004
    there is no deficiency of g6pd (rbc).
    Descrizione

    Deficiency of g6pd

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0391941 (Glucose-6-phosphate dehydrogenase Measurement)
    SNOMED
    104692005
    asymptomatic patients with disease progression and symptomatic patients.
    Descrizione

    Disease characteristics

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0242656 (Disease Progression)
    SNOMED
    246453008
    LOINC
    LP121764-7
    Exclusion Criteria
    Descrizione

    Exclusion Criteria

    Alias
    UMLS CUI
    C0680251 (Exclusion Criteria)

    Similar models

    Eligibility Acute Myeloid Leukemia NCT00329498

    Name
    genere
    Description | Question | Decode (Coded Value)
    Tipo di dati
    Alias
    Item Group
    C1512693 (UMLS CUI)
    AML or MDS
    Item
    patients should have aml or mds according to new who classification, with minimum of 5% blasts in peripheral blood.
    boolean
    C0023467 (UMLS CUI [1])
    C3463824 (UMLS CUI [2])
    Treatment history
    Item
    there must be a clear and acceptable reason for not receiving standard treatments (chemotherapy and/or stem cell transplantation); or standard treatments have already been given and this option exhausted with evidence of refractory disease.
    boolean
    C0087111 (UMLS CUI [1])
    Prior treatment
    Item
    prior treatments of any forms are allowed provided there is no potential residual beneficial effect and the patients are off treatment for at least 4 weeks, with estimated life expectancy of at least 2 months.
    boolean
    C0087111 (UMLS CUI [1])
    Bone marrow
    Item
    adequate amount (4 ml) of bone marrow sent to the laboratory for cell culture studies.
    boolean
    C0005953 (UMLS CUI [1])
    Further restrictions
    Item
    there are no restrictions based on age, sex, or ethnicity except that adequate contraception must be practiced in women of childbearing ages. although aml is rare in children, pediatric patients will be accepted.
    boolean
    C0700589 (UMLS CUI [1])
    Deficiency of g6pd
    Item
    there is no deficiency of g6pd (rbc).
    boolean
    C0391941 (UMLS CUI [1])
    Disease characteristics
    Item
    asymptomatic patients with disease progression and symptomatic patients.
    boolean
    C0242656 (UMLS CUI [1])
    Item Group
    C0680251 (UMLS CUI)

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