0 Valutazioni

ID

12788

Descrizione

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene; ODM derived from: https://clinicaltrials.gov/show/NCT00710892

collegamento

https://clinicaltrials.gov/show/NCT00710892

Keywords

  1. 21/12/15 21/12/15 -
Caricato su

21 dicembre 2015

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0

Commenti del modello :

Puoi commentare il modello dati qui. Tramite i fumetti nei gruppi di articoli e articoli è possibile aggiungere commenti a quelli in modo specifico.

Commenti del gruppo di articoli per :

Commenti dell'articolo per :


    Non ci sono commenti

    Per scaricare i modelli di dati devi essere registrato. Per favore accesso o registrati GRATIS.

    Eligibility Acute Lymphoblastic Leukemia NCT00710892

    Eligibility Acute Lymphoblastic Leukemia NCT00710892

    Inclusion Criteria
    Descrizione

    Inclusion Criteria

    Alias
    UMLS CUI
    C1512693 (Inclusion)
    at the time of transplant:
    Descrizione

    time of transplant

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3262320 (Date transplant:Time Stamp -- Date and Time:Point in time:^Patient:Quantitative)
    LOINC
    68445-6
    patients (up to 65 years of age) with:
    Descrizione

    age

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    all or high grade nhl that is stage iii or iv and has relapsed or is considered to be primary refractory disease.
    Descrizione

    all or high grade nhl

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0023449 (Acute lymphocytic leukemia)
    SNOMED
    91857003
    LOINC
    LA31346-2
    UMLS CUI [2]
    C0024305 (Lymphoma, Non-Hodgkin)
    SNOMED
    1929004
    myelodysplastic syndrome.
    Descrizione

    myelodysplastic syndrome

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3463824 (MYELODYSPLASTIC SYNDROME)
    SNOMED
    109995007
    aml after first relapse or with primary refractory disease.
    Descrizione

    aml after first relapse or with primary refractory disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C2367456 (acute myelogenous leukemia in relapse)
    UMLS CUI [2]
    C1514815 (Refractory Disease)
    cml
    Descrizione

    cml

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0279899 (cellular diagnosis, chronic myelogenous leukemia)
    hemophagocytic lymphohistiocytosis (hlh); familial hemophagocytic lymphohistiocytosis (flh); viral-associated hemophagocytic syndrome (vahs); patients with severe chronic active epstein barr virus infection (scaebv) with predilection for t or nk cell malignancy; x-linked lymphoproliferative disease (xlp)
    Descrizione

    hemophagocytic lymphohistiocytosis (hlh); familial hemophagocytic lymphohistiocytosis (flh); viral-associated hemophagocytic syndrome (vahs); patients with severe chronic active epstein barr virus infection

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0024291 (Lymphohistiocytosis, Hemophagocytic)
    SNOMED
    234437005
    UMLS CUI [2]
    C0272199 (Familial Hemophagocytic Lymphocytosis)
    SNOMED
    398250003
    UMLS CUI [3]
    C0019068 (Reactive Hemophagocytic Syndrome)
    SNOMED
    190959006
    UMLS CUI [4]
    C0549463 (X-Linked Lymphoproliferative Disorder)
    SNOMED
    77121009
    UMLS CUI [5]
    C0149678 (Epstein-Barr Virus Infections)
    SNOMED
    240530001
    lack of suitable conventional donor (i.e. 5/6 or 6/6 related, or 5/6 or 6/6 unrelated donor) or presence of a rapidly progressive disease not permitting time to identify an unrelated donor.
    Descrizione

    lack of suitable conventional donor (i.e. 5/6 or 6/6 related, or 5/6 or 6/6 unrelated donor) or presence of a rapidly progressive disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0013018 (Donor person)
    UMLS CUI [2]
    C1335499 (Progressive Disease)
    at the time of allodepleted t cell infusion:
    Descrizione

    allodepleted t cell infusion

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3897408 (T Cell-Depleted Donor Lymphocyte Infusion)
    engrafted with anc greater than 500.
    Descrizione

    anc

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0948762 (Absolute neutrophil count)
    must have greater than or equal to 50 percent donor chimerism in either peripheral blood or bone marrow, or relapse of their original disease.
    Descrizione

    must have greater than or equal to 50 percent donor chimerism in either peripheral blood or bone marrow, or relapse of their original disease.

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3250865 (chimerism analysis with cell selection)
    UMLS CUI [2]
    C0277556 (Recurrent disease)
    SNOMED
    58184002
    life expectancy greater than 30 days
    Descrizione

    life expectancy

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0023671 (Life Expectancy)
    lansky/karnofsky scores greater than or equal to 60
    Descrizione

    karnofsky

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0206065 (Karnofsky Performance Status)
    SNOMED
    273546003
    LOINC
    LP267177-6
    absence of severe renal disease (creatinine greater than 2x normal for age)
    Descrizione

    renal disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0022658 (Kidney Diseases)
    SNOMED
    90708001
    absence of severe hepatic disease (direct bilirubin greater than 2 mg/dl, or sgot greater than 200
    Descrizione

    liver disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0023895 (Liver diseases)
    SNOMED
    235856003
    LOINC
    LA17774-3
    oxygen saturation greater than 94 percent on room air
    Descrizione

    spo2

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0428179 (Measurement of oxygen saturation at periphery)
    SNOMED
    250554003
    patient/guardian able to give informed consent
    Descrizione

    informed consent

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0021430 (Informed Consent)
    Exclusion Criteria
    Descrizione

    Exclusion Criteria

    Alias
    UMLS CUI
    C0680251 (Exclusion Criteria)
    at the time of transplant:
    Descrizione

    at the time of transplant

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3262320 (Date transplant:Time Stamp -- Date and Time:Point in time:^Patient:Quantitative)
    LOINC
    68445-6
    pregnancy
    Descrizione

    pregnancy test only required for at-risk individuals, defined as female patients of childbearing potential who have received a reduced-intensity conditioning regimen.

    Tipo di dati

    boolean

    at the time of allodepleted t cell infusion:
    Descrizione

    at the time of allodepleted t cell infusion

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3897408 (T Cell-Depleted Donor Lymphocyte Infusion)
    gvhd
    Descrizione

    gvhd

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0018133 (Graft-vs-Host Disease)
    SNOMED
    234646005
    severe intercurrent infection
    Descrizione

    infection

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0009450 (Communicable Diseases)
    SNOMED
    189822004
    pregnancy
    Descrizione

    pregnancy test only required for at-risk individuals, defined as female patients of childbearing potential who have received a reduced-intensity conditioning regimen.

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0549206 (Patient currently pregnant)
    SNOMED
    77386006
    LOINC
    LA14670-6
    other investigational drugs in the prior 30 days
    Descrizione

    study subject participation status

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C2348568 (Study Subject Participation Status)

    Similar models

    Eligibility Acute Lymphoblastic Leukemia NCT00710892

    Name
    genere
    Description | Question | Decode (Coded Value)
    Tipo di dati
    Alias
    Item Group
    C1512693 (UMLS CUI)
    time of transplant
    Item
    at the time of transplant:
    boolean
    C3262320 (UMLS CUI [1])
    age
    Item
    patients (up to 65 years of age) with:
    boolean
    C0001779 (UMLS CUI [1])
    all or high grade nhl
    Item
    all or high grade nhl that is stage iii or iv and has relapsed or is considered to be primary refractory disease.
    boolean
    C0023449 (UMLS CUI [1])
    C0024305 (UMLS CUI [2])
    myelodysplastic syndrome
    Item
    myelodysplastic syndrome.
    boolean
    C3463824 (UMLS CUI [1])
    aml after first relapse or with primary refractory disease
    Item
    aml after first relapse or with primary refractory disease.
    boolean
    C2367456 (UMLS CUI [1])
    C1514815 (UMLS CUI [2])
    cml
    Item
    cml
    boolean
    C0279899 (UMLS CUI [1])
    hemophagocytic lymphohistiocytosis (hlh); familial hemophagocytic lymphohistiocytosis (flh); viral-associated hemophagocytic syndrome (vahs); patients with severe chronic active epstein barr virus infection
    Item
    hemophagocytic lymphohistiocytosis (hlh); familial hemophagocytic lymphohistiocytosis (flh); viral-associated hemophagocytic syndrome (vahs); patients with severe chronic active epstein barr virus infection (scaebv) with predilection for t or nk cell malignancy; x-linked lymphoproliferative disease (xlp)
    boolean
    C0024291 (UMLS CUI [1])
    C0272199 (UMLS CUI [2])
    C0019068 (UMLS CUI [3])
    C0549463 (UMLS CUI [4])
    C0149678 (UMLS CUI [5])
    lack of suitable conventional donor (i.e. 5/6 or 6/6 related, or 5/6 or 6/6 unrelated donor) or presence of a rapidly progressive disease
    Item
    lack of suitable conventional donor (i.e. 5/6 or 6/6 related, or 5/6 or 6/6 unrelated donor) or presence of a rapidly progressive disease not permitting time to identify an unrelated donor.
    boolean
    C0013018 (UMLS CUI [1])
    C1335499 (UMLS CUI [2])
    allodepleted t cell infusion
    Item
    at the time of allodepleted t cell infusion:
    boolean
    C3897408 (UMLS CUI [1])
    anc
    Item
    engrafted with anc greater than 500.
    boolean
    C0948762 (UMLS CUI [1])
    must have greater than or equal to 50 percent donor chimerism in either peripheral blood or bone marrow, or relapse of their original disease.
    Item
    must have greater than or equal to 50 percent donor chimerism in either peripheral blood or bone marrow, or relapse of their original disease.
    boolean
    C3250865 (UMLS CUI [1])
    C0277556 (UMLS CUI [2])
    life expectancy
    Item
    life expectancy greater than 30 days
    boolean
    C0023671 (UMLS CUI [1])
    karnofsky
    Item
    lansky/karnofsky scores greater than or equal to 60
    boolean
    C0206065 (UMLS CUI [1])
    renal disease
    Item
    absence of severe renal disease (creatinine greater than 2x normal for age)
    boolean
    C0022658 (UMLS CUI [1])
    liver disease
    Item
    absence of severe hepatic disease (direct bilirubin greater than 2 mg/dl, or sgot greater than 200
    boolean
    C0023895 (UMLS CUI [1])
    spo2
    Item
    oxygen saturation greater than 94 percent on room air
    boolean
    C0428179 (UMLS CUI [1])
    informed consent
    Item
    patient/guardian able to give informed consent
    boolean
    C0021430 (UMLS CUI [1])
    Item Group
    C0680251 (UMLS CUI)
    at the time of transplant
    Item
    at the time of transplant:
    boolean
    C3262320 (UMLS CUI [1])
    pregnancy
    Item
    pregnancy
    boolean
    at the time of allodepleted t cell infusion
    Item
    at the time of allodepleted t cell infusion:
    boolean
    C3897408 (UMLS CUI [1])
    gvhd
    Item
    gvhd
    boolean
    C0018133 (UMLS CUI [1])
    infection
    Item
    severe intercurrent infection
    boolean
    C0009450 (UMLS CUI [1])
    pregnancy
    Item
    pregnancy
    boolean
    C0549206 (UMLS CUI [1])
    study subject participation status
    Item
    other investigational drugs in the prior 30 days
    boolean
    C2348568 (UMLS CUI [1])

    Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

    Watch Tutorial