ID
11710
Beskrivning
Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing. This is probably an effect of improving diagnostics of myocardial infraction without persistent ST segment elevation in ECG, due to routine Troponin serum level evaluation and better primary prevention. This fact makes the search for the optimal treatment for patients with acute coronary event without persistent ST segment elevation in ECG, including both patients intended for pharmacological and invasive treatment percutaneous coronary intervention (PCI) or coronary artery byppass grafting (CABG). Patients undergoing invasive treatment for acute coronary event, have higher risk rate, than those with stabile angina pectoris. The authors of this study want to evaluate, whether the proportional use of platelet GP IIb/IIIa receptor antagonist - eptifibatide in patients undergoing CABG results in improvement of short-, and long time results in those patients. Eptifibatide ( Integrilin) a cyclic heptapeptide antagonist of the GP IIb/IIIa integrin receptor, is an intravenous antagonist with rapid onset and short half-life. https://clinicaltrials.gov/ct2/show/NCT01863134
Länk
https://clinicaltrials.gov/ct2/show/NCT01863134
Nyckelord
Versioner (1)
- 2015-07-28 2015-07-28 -
Uppladdad den
28 juli 2015
DOI
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Licens
Creative Commons BY 4.0
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Eligibility Eptifibatide Acute Coronary Syndrome NCT01863134
Eligibility criteria
- StudyEvent: ODM
Beskrivning
Exclusion Criteria
Beskrivning
Women who are pregnant or nursing.
Datatyp
boolean
Alias
- UMLS CUI-1
- C0549206
Beskrivning
Angina lasting longer than 24h
Datatyp
boolean
Alias
- UMLS CUI-1
- C0002962
Beskrivning
ST segment elevation - Pardy wave
Datatyp
boolean
Alias
- UMLS CUI-1
- C0520886
Beskrivning
age over 75 years
Datatyp
boolean
Alias
- UMLS CUI-1
- C0001779
Beskrivning
history of revascularization procedure during last 6 months (PTCA, CABG)
Datatyp
boolean
Alias
- UMLS CUI-1
- C0027056
Beskrivning
chronic heart failure (NYHA III or IV) during pre-hospitalization period
Datatyp
boolean
Alias
- UMLS CUI-1
- C0018802
Beskrivning
History of bleeding from gastrointestinal tract system during last 30 days
Datatyp
boolean
Alias
- UMLS CUI-1
- C0017181
Beskrivning
History of bleeding from genitourinary system during last 30 days
Datatyp
boolean
Alias
- UMLS CUI-1
- C0919591
Beskrivning
history of intracranial lesions or stroke
Datatyp
boolean
Alias
- UMLS CUI-1
- C0559159
Beskrivning
history of major surgery during last 6 weeks
Datatyp
boolean
Alias
- UMLS CUI-1
- C0679637
Beskrivning
history of trauma during last 6 weeks
Datatyp
boolean
Alias
- UMLS CUI-1
- C3714660
Beskrivning
history of hemorrhagic diathesis
Datatyp
boolean
Alias
- UMLS CUI-1
- C3251812
Beskrivning
thrombocytopenia < 100 000/mm3
Datatyp
boolean
Alias
- UMLS CUI-1
- C0040034
Beskrivning
anticoagulant therapy with INR>2,0
Datatyp
boolean
Alias
- UMLS CUI-1
- C0003280
Beskrivning
significant hepatic failure
Datatyp
boolean
Alias
- UMLS CUI-1
- C0085605
Beskrivning
significant renal failure with serum creatinine>2,0 mg%
Datatyp
boolean
Alias
- UMLS CUI-1
- C0035078
Beskrivning
elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment
Datatyp
boolean
Alias
- UMLS CUI-1
- C0020538
Beskrivning
allergy to drugs or any therapeutic agent
Datatyp
boolean
Alias
- UMLS CUI-1
- C0013182
Similar models
Eligibility criteria
- StudyEvent: ODM