ID
11710
Beschrijving
Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing. This is probably an effect of improving diagnostics of myocardial infraction without persistent ST segment elevation in ECG, due to routine Troponin serum level evaluation and better primary prevention. This fact makes the search for the optimal treatment for patients with acute coronary event without persistent ST segment elevation in ECG, including both patients intended for pharmacological and invasive treatment percutaneous coronary intervention (PCI) or coronary artery byppass grafting (CABG). Patients undergoing invasive treatment for acute coronary event, have higher risk rate, than those with stabile angina pectoris. The authors of this study want to evaluate, whether the proportional use of platelet GP IIb/IIIa receptor antagonist - eptifibatide in patients undergoing CABG results in improvement of short-, and long time results in those patients. Eptifibatide ( Integrilin) a cyclic heptapeptide antagonist of the GP IIb/IIIa integrin receptor, is an intravenous antagonist with rapid onset and short half-life. https://clinicaltrials.gov/ct2/show/NCT01863134
Link
https://clinicaltrials.gov/ct2/show/NCT01863134
Trefwoorden
Versies (1)
- 28-07-15 28-07-15 -
Geüploaded op
28 juli 2015
DOI
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Licentie
Creative Commons BY 4.0
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Eligibility Eptifibatide Acute Coronary Syndrome NCT01863134
Eligibility criteria
- StudyEvent: ODM
Beschrijving
Exclusion Criteria
Beschrijving
Women who are pregnant or nursing.
Datatype
boolean
Alias
- UMLS CUI-1
- C0549206
Beschrijving
Angina lasting longer than 24h
Datatype
boolean
Alias
- UMLS CUI-1
- C0002962
Beschrijving
ST segment elevation - Pardy wave
Datatype
boolean
Alias
- UMLS CUI-1
- C0520886
Beschrijving
age over 75 years
Datatype
boolean
Alias
- UMLS CUI-1
- C0001779
Beschrijving
history of revascularization procedure during last 6 months (PTCA, CABG)
Datatype
boolean
Alias
- UMLS CUI-1
- C0027056
Beschrijving
chronic heart failure (NYHA III or IV) during pre-hospitalization period
Datatype
boolean
Alias
- UMLS CUI-1
- C0018802
Beschrijving
History of bleeding from gastrointestinal tract system during last 30 days
Datatype
boolean
Alias
- UMLS CUI-1
- C0017181
Beschrijving
History of bleeding from genitourinary system during last 30 days
Datatype
boolean
Alias
- UMLS CUI-1
- C0919591
Beschrijving
history of intracranial lesions or stroke
Datatype
boolean
Alias
- UMLS CUI-1
- C0559159
Beschrijving
history of major surgery during last 6 weeks
Datatype
boolean
Alias
- UMLS CUI-1
- C0679637
Beschrijving
history of trauma during last 6 weeks
Datatype
boolean
Alias
- UMLS CUI-1
- C3714660
Beschrijving
history of hemorrhagic diathesis
Datatype
boolean
Alias
- UMLS CUI-1
- C3251812
Beschrijving
thrombocytopenia < 100 000/mm3
Datatype
boolean
Alias
- UMLS CUI-1
- C0040034
Beschrijving
anticoagulant therapy with INR>2,0
Datatype
boolean
Alias
- UMLS CUI-1
- C0003280
Beschrijving
significant hepatic failure
Datatype
boolean
Alias
- UMLS CUI-1
- C0085605
Beschrijving
significant renal failure with serum creatinine>2,0 mg%
Datatype
boolean
Alias
- UMLS CUI-1
- C0035078
Beschrijving
elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment
Datatype
boolean
Alias
- UMLS CUI-1
- C0020538
Beschrijving
allergy to drugs or any therapeutic agent
Datatype
boolean
Alias
- UMLS CUI-1
- C0013182
Similar models
Eligibility criteria
- StudyEvent: ODM