ID
11710
Description
Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing. This is probably an effect of improving diagnostics of myocardial infraction without persistent ST segment elevation in ECG, due to routine Troponin serum level evaluation and better primary prevention. This fact makes the search for the optimal treatment for patients with acute coronary event without persistent ST segment elevation in ECG, including both patients intended for pharmacological and invasive treatment percutaneous coronary intervention (PCI) or coronary artery byppass grafting (CABG). Patients undergoing invasive treatment for acute coronary event, have higher risk rate, than those with stabile angina pectoris. The authors of this study want to evaluate, whether the proportional use of platelet GP IIb/IIIa receptor antagonist - eptifibatide in patients undergoing CABG results in improvement of short-, and long time results in those patients. Eptifibatide ( Integrilin) a cyclic heptapeptide antagonist of the GP IIb/IIIa integrin receptor, is an intravenous antagonist with rapid onset and short half-life. https://clinicaltrials.gov/ct2/show/NCT01863134
Lien
https://clinicaltrials.gov/ct2/show/NCT01863134
Mots-clés
Versions (1)
- 28/07/2015 28/07/2015 -
Téléchargé le
28 juillet 2015
DOI
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Licence
Creative Commons BY 4.0
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Eligibility Eptifibatide Acute Coronary Syndrome NCT01863134
Eligibility criteria
- StudyEvent: ODM
Description
Exclusion Criteria
Description
Women who are pregnant or nursing.
Type de données
boolean
Alias
- UMLS CUI-1
- C0549206
Description
Angina lasting longer than 24h
Type de données
boolean
Alias
- UMLS CUI-1
- C0002962
Description
ST segment elevation - Pardy wave
Type de données
boolean
Alias
- UMLS CUI-1
- C0520886
Description
age over 75 years
Type de données
boolean
Alias
- UMLS CUI-1
- C0001779
Description
history of revascularization procedure during last 6 months (PTCA, CABG)
Type de données
boolean
Alias
- UMLS CUI-1
- C0027056
Description
chronic heart failure (NYHA III or IV) during pre-hospitalization period
Type de données
boolean
Alias
- UMLS CUI-1
- C0018802
Description
History of bleeding from gastrointestinal tract system during last 30 days
Type de données
boolean
Alias
- UMLS CUI-1
- C0017181
Description
History of bleeding from genitourinary system during last 30 days
Type de données
boolean
Alias
- UMLS CUI-1
- C0919591
Description
history of intracranial lesions or stroke
Type de données
boolean
Alias
- UMLS CUI-1
- C0559159
Description
history of major surgery during last 6 weeks
Type de données
boolean
Alias
- UMLS CUI-1
- C0679637
Description
history of trauma during last 6 weeks
Type de données
boolean
Alias
- UMLS CUI-1
- C3714660
Description
history of hemorrhagic diathesis
Type de données
boolean
Alias
- UMLS CUI-1
- C3251812
Description
thrombocytopenia < 100 000/mm3
Type de données
boolean
Alias
- UMLS CUI-1
- C0040034
Description
anticoagulant therapy with INR>2,0
Type de données
boolean
Alias
- UMLS CUI-1
- C0003280
Description
significant hepatic failure
Type de données
boolean
Alias
- UMLS CUI-1
- C0085605
Description
significant renal failure with serum creatinine>2,0 mg%
Type de données
boolean
Alias
- UMLS CUI-1
- C0035078
Description
elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment
Type de données
boolean
Alias
- UMLS CUI-1
- C0020538
Description
allergy to drugs or any therapeutic agent
Type de données
boolean
Alias
- UMLS CUI-1
- C0013182
Similar models
Eligibility criteria
- StudyEvent: ODM