ID
11710
Beschreibung
Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing. This is probably an effect of improving diagnostics of myocardial infraction without persistent ST segment elevation in ECG, due to routine Troponin serum level evaluation and better primary prevention. This fact makes the search for the optimal treatment for patients with acute coronary event without persistent ST segment elevation in ECG, including both patients intended for pharmacological and invasive treatment percutaneous coronary intervention (PCI) or coronary artery byppass grafting (CABG). Patients undergoing invasive treatment for acute coronary event, have higher risk rate, than those with stabile angina pectoris. The authors of this study want to evaluate, whether the proportional use of platelet GP IIb/IIIa receptor antagonist - eptifibatide in patients undergoing CABG results in improvement of short-, and long time results in those patients. Eptifibatide ( Integrilin) a cyclic heptapeptide antagonist of the GP IIb/IIIa integrin receptor, is an intravenous antagonist with rapid onset and short half-life. https://clinicaltrials.gov/ct2/show/NCT01863134
Link
https://clinicaltrials.gov/ct2/show/NCT01863134
Stichworte
Versionen (1)
- 28.07.15 28.07.15 -
Hochgeladen am
28. Juli 2015
DOI
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Lizenz
Creative Commons BY 4.0
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Eligibility Eptifibatide Acute Coronary Syndrome NCT01863134
Eligibility criteria
- StudyEvent: ODM
Beschreibung
Exclusion Criteria
Beschreibung
Women who are pregnant or nursing.
Datentyp
boolean
Alias
- UMLS CUI-1
- C0549206
Beschreibung
Angina lasting longer than 24h
Datentyp
boolean
Alias
- UMLS CUI-1
- C0002962
Beschreibung
ST segment elevation - Pardy wave
Datentyp
boolean
Alias
- UMLS CUI-1
- C0520886
Beschreibung
age over 75 years
Datentyp
boolean
Alias
- UMLS CUI-1
- C0001779
Beschreibung
history of revascularization procedure during last 6 months (PTCA, CABG)
Datentyp
boolean
Alias
- UMLS CUI-1
- C0027056
Beschreibung
chronic heart failure (NYHA III or IV) during pre-hospitalization period
Datentyp
boolean
Alias
- UMLS CUI-1
- C0018802
Beschreibung
History of bleeding from gastrointestinal tract system during last 30 days
Datentyp
boolean
Alias
- UMLS CUI-1
- C0017181
Beschreibung
History of bleeding from genitourinary system during last 30 days
Datentyp
boolean
Alias
- UMLS CUI-1
- C0919591
Beschreibung
history of intracranial lesions or stroke
Datentyp
boolean
Alias
- UMLS CUI-1
- C0559159
Beschreibung
history of major surgery during last 6 weeks
Datentyp
boolean
Alias
- UMLS CUI-1
- C0679637
Beschreibung
history of trauma during last 6 weeks
Datentyp
boolean
Alias
- UMLS CUI-1
- C3714660
Beschreibung
history of hemorrhagic diathesis
Datentyp
boolean
Alias
- UMLS CUI-1
- C3251812
Beschreibung
thrombocytopenia < 100 000/mm3
Datentyp
boolean
Alias
- UMLS CUI-1
- C0040034
Beschreibung
anticoagulant therapy with INR>2,0
Datentyp
boolean
Alias
- UMLS CUI-1
- C0003280
Beschreibung
significant hepatic failure
Datentyp
boolean
Alias
- UMLS CUI-1
- C0085605
Beschreibung
significant renal failure with serum creatinine>2,0 mg%
Datentyp
boolean
Alias
- UMLS CUI-1
- C0035078
Beschreibung
elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment
Datentyp
boolean
Alias
- UMLS CUI-1
- C0020538
Beschreibung
allergy to drugs or any therapeutic agent
Datentyp
boolean
Alias
- UMLS CUI-1
- C0013182
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Eligibility criteria
- StudyEvent: ODM