Exclusion Criteria
Patients with severe renal function disorders (Creatinine clearance < 20 ml/min or Patients with moderate or severe disorders of hepatic function
boolean
Concomitant treatment with drugs known to affect sex hormonal status and tamoxifen
boolean
Patients with ductal carcinoma in situ (DCIS) without primary diagnosis of early breast cancer (M0)
boolean
Evidence of any significant clinical disorder or laboratory finding which in the opinion of the investigator, makes it undesirable for the patient to participate in the program
boolean