pp_date
Item
Date of assessment
date
Item
Any proof of malignancy? Please specify in comorbidities
integer
Code List
Any proof of malignancy? Please specify in comorbidities
Item
Underlying material for histopathological evaluation
text
Code List
Underlying material for histopathological evaluation
CL Item
Cryobiopsy (cryo)
CL Item
Transthoracic needle biopsy (transthoraxneedle)
CL Item
Open Lung Biopsy by VATS (vats)
CL Item
Open Lung Biopsy by conventional thoracotomy (thoracotomy)
CL Item
Explanted lung (expllung)
CL Item
Resection (resect)
CL Item
Autopsy (autopsy)
Item
Lymph node station right: 1. Supraclavicular
integer
Code List
Lymph node station right: 1. Supraclavicular
Item
2. Upper tracheal
integer
Code List
2. Upper tracheal
Item
3. Prevascular
integer
Item
4. Lower paratracheal
integer
Code List
4. Lower paratracheal
Item
5. Subaortic
integer
Item
6. AP window
integer
Item
7. Subcarinal
integer
Item
8. Paraesophagheal
integer
Code List
8. Paraesophagheal
Item
9. Pulmonary ligament
integer
Code List
9. Pulmonary ligament
Item
11. Interlobar
integer
Item
Lymph node station left: 1. Supraclavicular
integer
Code List
Lymph node station left: 1. Supraclavicular
Item
2. Upper tracheal
integer
Code List
2. Upper tracheal
Item
3. Prevascular
integer
Item
4. Lower paratracheal
integer
Code List
4. Lower paratracheal
Item
5. Subaortic
integer
Item
6. AP window
integer
Item
7. Subcarinal
integer
Item
8. Paraesophagheal
integer
Code List
8. Paraesophagheal
Item
9. Pulmonary ligament
integer
Code List
9. Pulmonary ligament
Item
11. Interlobar
integer
Item
Location biopsy upper lobe right: 1. Apical
integer
Code List
Location biopsy upper lobe right: 1. Apical
Item
2. Posterior
integer
Item
Location biopsy middle lobe right: 4. Lateral
integer
Code List
Location biopsy middle lobe right: 4. Lateral
Item
Location biopsy lower lobe right: 6. Superior
integer
Code List
Location biopsy lower lobe right: 6. Superior
Item
7. Med. basal
integer
Item
8. Lat. basal
integer
Item
9. Lat. basal
integer
Item
10. Post basal
integer
Item
Location biopsy upper lobe left: 1-2 Apical posterior
integer
Code List
Location biopsy upper lobe left: 1-2 Apical posterior
Item
4. Superior (Lingula)
integer
Code List
4. Superior (Lingula)
Item
5. Inferior (Lingula)
integer
Code List
5. Inferior (Lingula)
Item
Location biopsy lower lobe left: 6. Superior
integer
Code List
Location biopsy lower lobe left: 6. Superior
Item
7-8. Ant. basal
integer
Code List
7-8. Ant. basal
Item
9. Lat. basal
integer
Item
10. Post. basal
integer
Code List
10. Post. basal
Item
IIP patterns (as based on most recent ATS/ERS guidelines)
integer
Code List
IIP patterns (as based on most recent ATS/ERS guidelines)
Item
IIP patterns UIP
integer
Code List
IIP patterns UIP
Item
UIP criteria Choose from drop down: definite, probable, indeterminate Dense fibrosis with architectural distortion
integer
Code List
UIP criteria Choose from drop down: definite, probable, indeterminate Dense fibrosis with architectural distortion
Item
Predominant subpleural and/or paraseptal distribution of fibrosis
integer
Code List
Predominant subpleural and/or paraseptal distribution of fibrosis
Item
Patchy involvement of lung parenchyma by fibrosis
integer
Code List
Patchy involvement of lung parenchyma by fibrosis
Item
Fibroblast foci
integer
Code List
Fibroblast foci
Item
Honeycombing
integer
Item
Absence of features suggesting an alternate diagnosis
integer
Code List
Absence of features suggesting an alternate diagnosis
Item
Some histologic features from def. UIP
integer
Code List
Some histologic features from def. UIP
Item
Fibrosis with or without architectural distortion
integer
Code List
Fibrosis with or without architectural distortion
CL Item
Definite UIP (definite)
CL Item
Probable UIP (probable)
CL Item
Indeterminate UIP (indeterminate)
pp_uip_definite
Item
Suggested diagnosis: Definite UIP criteria
text
pp_uip_probable
Item
Suggested diagnosis: Probable UIP criteria
text
pp_uip_indeterminate
Item
Suggested diagnosis: Indeterminate UIP criteria
text
Item
NSIP - Cellular
integer
Code List
NSIP - Cellular
Item
Cellular interstitial pneumonia; lymphocytic or plasmacytic
integer
Code List
Cellular interstitial pneumonia; lymphocytic or plasmacytic
Item
Diffuse and uniform inflammation ("temporal homogeneity")
integer
Code List
Diffuse and uniform inflammation ("temporal homogeneity")
Item
Loose interstitial fibrosis
integer
Code List
Loose interstitial fibrosis
Item
Preserved architecture
integer
Code List
Preserved architecture
Item
NSIP - Fibrotic
integer
Code List
NSIP - Fibrotic
Item
Depletion of inflammatory cells
integer
Code List
Depletion of inflammatory cells
Item
Dense fiber-rich interstitial fibrosis
integer
Code List
Dense fiber-rich interstitial fibrosis
Item
Preserved architecture
integer
Code List
Preserved architecture
pp_aip_discription
Item
AIP - diffuse alveolar damage, almost completely identical to acute respiratory distress syndrome / diffuse alveolar damage morphologically
text
Item
AIP - Exudative phase
integer
Code List
AIP - Exudative phase
Item
Hyaline membranes in alveolar duct or sacs; scattered or not apparent
integer
Code List
Hyaline membranes in alveolar duct or sacs; scattered or not apparent
Item
Interstitial and intra-alveolar edema
integer
Code List
Interstitial and intra-alveolar edema
Item
Collapsed alveoli
integer
Code List
Collapsed alveoli
Item
Denudation and necrosis of type I pneumocytes
integer
Code List
Denudation and necrosis of type I pneumocytes
Item
Hemorrhage - usually mild
integer
Code List
Hemorrhage - usually mild
Item
AIP - Proliferative / organizing phase
integer
Code List
AIP - Proliferative / organizing phase
Item
Organizing pneumonia with / without remnants of hyaline membrane
integer
Code List
Organizing pneumonia with / without remnants of hyaline membrane
Item
Interstitial and intra-alveolar proliferation of fibroblasts / myofibroblasts
integer
Code List
Interstitial and intra-alveolar proliferation of fibroblasts / myofibroblasts
Item
Lymphocytic infiltration; usually more prominent than in acute respiratory distress syndrome
integer
Code List
Lymphocytic infiltration; usually more prominent than in acute respiratory distress syndrome
Item
Proliferation of type II pneumocytes with occasional cellular atypia
integer
Code List
Proliferation of type II pneumocytes with occasional cellular atypia
Item
Endothelial injury and fibrinous thromboembolism in arterioles / arteries
integer
Code List
Endothelial injury and fibrinous thromboembolism in arterioles / arteries
Item
AIP - Fibrosis phase
integer
Code List
AIP - Fibrosis phase
Item
Diffuse collagenous fibrosis
integer
Code List
Diffuse collagenous fibrosis
Item
Microscopic honeycomb-like change
integer
Code List
Microscopic honeycomb-like change
Item
Traction bronchiolectasis
integer
Code List
Traction bronchiolectasis
Item
Squamous metaplasia
integer
Code List
Squamous metaplasia
Item
Organized thrombus
integer
Code List
Organized thrombus
Item
Thickening of pleura with dilatation of lymphatic / blood vessels
integer
Code List
Thickening of pleura with dilatation of lymphatic / blood vessels
Item
OP Fibroblastic plugs in alveolar sacs and ducts (organizing pneumonia) and bronchiolar lumen (bronchiolitis obliterans)
integer
Code List
OP Fibroblastic plugs in alveolar sacs and ducts (organizing pneumonia) and bronchiolar lumen (bronchiolitis obliterans)
Item
Formed by spindled fibroblasts in pale staining matrix of immature loose collagen with polypoid shape (Masson body) or serpiginous or elongated form
integer
Code List
Formed by spindled fibroblasts in pale staining matrix of immature loose collagen with polypoid shape (Masson body) or serpiginous or elongated form
Item
Organizing pneumonia sometimes extends from one alveolus to the next one through interalveolar fenestrae (butterfly pattern)
integer
Code List
Organizing pneumonia sometimes extends from one alveolus to the next one through interalveolar fenestrae (butterfly pattern)
Item
Thickened alveolar septa with lymphocytes
integer
Code List
Thickened alveolar septa with lymphocytes
Item
Alveolar architecture is usually preserved in cryptogenic organizing pneumonia
integer
Code List
Alveolar architecture is usually preserved in cryptogenic organizing pneumonia
Item
Foamy macrophage accumulation in surrounding airspace may be present
integer
Code List
Foamy macrophage accumulation in surrounding airspace may be present
Item
RB-ILD Lightly pigmented (smoker's) macrophages limited to distal airspaces and peribronchiolar airspaces
integer
Code List
RB-ILD Lightly pigmented (smoker's) macrophages limited to distal airspaces and peribronchiolar airspaces
Item
Pigment within macrophage cytoplasm is yellow to light brown and finely granular
integer
Code List
Pigment within macrophage cytoplasm is yellow to light brown and finely granular
Item
Minimal to absent peribronchiolar interstitial thickening by fibrosis
integer
Code List
Minimal to absent peribronchiolar interstitial thickening by fibrosis
Item
No diffuse interstitial fibrosis or inflammation
integer
Code List
No diffuse interstitial fibrosis or inflammation
Item
DIP Diffuse and massive accumulation of intra-alveolar macrophages (smoker's macrophages)
integer
Code List
DIP Diffuse and massive accumulation of intra-alveolar macrophages (smoker's macrophages)
Item
Brown pigments
integer
Item
Giant cells can be also seen
integer
Code List
Giant cells can be also seen
Item
Diffuse and homogeneous involvement (similar to NSIP) along with alveolar macrophages
integer
Code List
Diffuse and homogeneous involvement (similar to NSIP) along with alveolar macrophages
Item
Lymphoid follicles and eosinophils are often present
integer
Code List
Lymphoid follicles and eosinophils are often present
Item
LIP Lymphoid follicles with germinal centers
integer
Code List
LIP Lymphoid follicles with germinal centers
Item
Bronchovascular bundles and interlobular septa are usually involved
integer
Code List
Bronchovascular bundles and interlobular septa are usually involved
Item
Alveolar structure is often inflated and disrupted
integer
Code List
Alveolar structure is often inflated and disrupted
Item
Typically CD8+ or CD4+ T cells or B cells predominate
integer
Code List
Typically CD8+ or CD4+ T cells or B cells predominate
Item
Interstitial or intra-alveolar giant cells
integer
Code List
Interstitial or intra-alveolar giant cells
Item
Intra-alveolar macrophages
integer
Code List
Intra-alveolar macrophages
Item
Type II pneumocyte hyperplasia
integer
Code List
Type II pneumocyte hyperplasia
Item
Cyst formation without marked fibrosis
integer
Code List
Cyst formation without marked fibrosis
Item
PPFE Linear subpleural elastofibrosis
integer
Code List
PPFE Linear subpleural elastofibrosis
Item
Onset in upper lung
integer
Code List
Onset in upper lung
Item
May be associated to UIP pattern in lower lung parts
integer
Code List
May be associated to UIP pattern in lower lung parts
Item
AFOP Dominant findings of intra-alveolar fibrin
integer
Code List
AFOP Dominant findings of intra-alveolar fibrin
Item
Involves more than 20% of the alveolar spaces in the lesion
integer
Code List
Involves more than 20% of the alveolar spaces in the lesion
Item
Neutrophils are usually scanty or absent
integer
Code List
Neutrophils are usually scanty or absent
Item
Organizing pneumonia: fibroblastic plugs in alveolar sacs and ducts with loose collagen matrix
integer
Code List
Organizing pneumonia: fibroblastic plugs in alveolar sacs and ducts with loose collagen matrix
Item
Diffuse and patchy distribution
integer
Code List
Diffuse and patchy distribution
Item
BPIP Peribronchiolar metaplasia
integer
Code List
BPIP Peribronchiolar metaplasia
Item
Peribronchiolar fibrosis with preserved architecture
integer
Code List
Peribronchiolar fibrosis with preserved architecture
Item
Under discussion
integer
Code List
Under discussion
Item
Langerhans Cell Histiocytosis (LCH)
integer
Code List
Langerhans Cell Histiocytosis (LCH)
Item
Accumulation of activated LCs organised into loose
integer
Code List
Accumulation of activated LCs organised into loose
Item
Infiltration with Lymphocytes and other inflammatory cells
integer
Code List
Infiltration with Lymphocytes and other inflammatory cells
Item
Abundance of pigmented macrophages
integer
Code List
Abundance of pigmented macrophages
Item
Granulomateous patterns
integer
Code List
Granulomateous patterns
Item
Granulomateous disease other than idiopathic sarcoidosis
integer
Code List
Granulomateous disease other than idiopathic sarcoidosis
Item
HP criteria - nonfibrotic Choose from drop down: definite, probable, indeterminate (based on ATS HP guideline) Cellular interstitial pneumonia (bronchiolocentric; cellular NSIP; lymphocyte-predominant)
integer
Code List
HP criteria - nonfibrotic Choose from drop down: definite, probable, indeterminate (based on ATS HP guideline) Cellular interstitial pneumonia (bronchiolocentric; cellular NSIP; lymphocyte-predominant)
Item
Cellular bronchiolitis (lymphocyte predominant; +/- OP with Masson bodies; +/- foamy macrophages)
integer
Code List
Cellular bronchiolitis (lymphocyte predominant; +/- OP with Masson bodies; +/- foamy macrophages)
Item
Poorly formed nonnecrotizing granulomas (loose clusters of epithelioid cells +/- intracytoplasmic inclusions; situated in peribronchiolar interstitium
integer
Code List
Poorly formed nonnecrotizing granulomas (loose clusters of epithelioid cells +/- intracytoplasmic inclusions; situated in peribronchiolar interstitium
Item
Absence of any of the following: plasma cells > lymphs; extensive lymphoid hyperplasia; extensive well-formed sarcoidal and/or necrotizing granulomas; aspirated particulates
integer
Code List
Absence of any of the following: plasma cells > lymphs; extensive lymphoid hyperplasia; extensive well-formed sarcoidal and/or necrotizing granulomas; aspirated particulates
CL Item
Definite HP criteria (definite)
CL Item
Probable HP criteria (probable)
CL Item
Indeterminate HP criteria (indeterminate)
pp_nf_granu_definite
Item
Suggested diagnosis: Definite nonfibrotic (cellular) HP criteria
text
pp_nf_granu_probable
Item
Suggested diagnosis: Probable nonfibrotic HP criteria
text
pp_nf_granu_indeter
Item
Suggested diagnosis: Indeterminate for non-fibrotic HP criteria
text
Item
HP criteria - fibrotic Choose from drop down: definite, probable, indeterminate (based on ATS HP guideline) Chronic fibrosing interstital pneumonia (architectural distortion
integer
Code List
HP criteria - fibrotic Choose from drop down: definite, probable, indeterminate (based on ATS HP guideline) Chronic fibrosing interstital pneumonia (architectural distortion
Item
Airway-centered fibrosis (opt. Peribronchiolar metaplasia or Bridging fibrosis)
integer
Code List
Airway-centered fibrosis (opt. Peribronchiolar metaplasia or Bridging fibrosis)
Item
Poorly formed non-necrotizing granulomas (opt. Cellular intestinal pneumonia or Cellular bronchiolitis or Organizing pneumonia AND Absence of features in any biopsy site such as plasma cells > lymphs
integer
Code List
Poorly formed non-necrotizing granulomas (opt. Cellular intestinal pneumonia or Cellular bronchiolitis or Organizing pneumonia AND Absence of features in any biopsy site such as plasma cells > lymphs
pp_f_granu_definite
Item
Definite fibrotic HP criteria
text
pp_f_granu_probable
Item
Probable nonfibrotic HP criteria
text
pp_f_granu_indeterm
Item
Indeterminate for fibrotic HP criteria
text
CL Item
Definite (definite)
CL Item
Probable (probable)
CL Item
Indeterminate (indeterminate)
Item
Sarcoidosis criteria as in ATS 2020 Sarcoidosis Guideline (choose appropriate) Presence of granuloma or nodular hyalinised fibrosis representing healed granulomas (scattered multinucleated giant cells may be detectable)
integer
Code List
Sarcoidosis criteria as in ATS 2020 Sarcoidosis Guideline (choose appropriate) Presence of granuloma or nodular hyalinised fibrosis representing healed granulomas (scattered multinucleated giant cells may be detectable)
Item
Granuloma are compact
integer
Code List
Granuloma are compact
Item
Fibrosis beginning at the granuloma periphery with extension centrally into the granuloma
integer
Code List
Fibrosis beginning at the granuloma periphery with extension centrally into the granuloma
Item
Lesions are perilymphatic
integer
Code List
Lesions are perilymphatic
Item
Sparse surrounding lymphocytic infiltrate
integer
Code List
Sparse surrounding lymphocytic infiltrate
Item
Microorganism stains and cultures negative
integer
Code List
Microorganism stains and cultures negative
Item
Granulomatous disease other than idiopathic sarcoidosis
text
Code List
Granulomatous disease other than idiopathic sarcoidosis
CL Item
Infectious (infectious)
CL Item
Non-infectious (non-infectious)
CL Item
Idiopathic (idiopathic)
CL Item
Bacteria (e.g. M. tuberculosis, MOTT, Brucella, Tropheryma whipplei, M. leprae, Francisella tularensis, Bartonella henselae, Coxiella burnetii) (bacteria)
CL Item
Fungi (Aspergillus, Histoplasma, Blastomyces, Coccidioides, Cryptococcus, Pneumocystis) (fungi)
CL Item
Viruses (Herpes Zoster) (virus)
CL Item
Parasites (Toxoplasma gondii, Schistosomes, Leishmania, Enterobius, Dirofilaria) (parasite)
CL Item
Malignancy (Lymphoma, lymphomatoid granulomatosis, sarcoid-like reaction to tumor, germ cell tumor) (malignancy)
CL Item
Autoimmune (ANCA-associated vasculitides, GLILD associated with CVID, rheumatoid nodules, Langerhans Cell histiocytosis, IgG4-related disease, inflammatory bowel diseases, primary biliary cholangitis, primary sclerosing cholangitis, autoimmune hepatitis) (autoimmune)
CL Item
Exposures (HP, "Hot tub lung syndrome", Pneumoconiosis (e.g. berylliosis), drug-induced ILD (e.g. treatment with checkpoint inhibitors), anti-TNF or biologicals, foreign body granulomatosis (e.g. talc, tattoo), steatosis (lipogranulomas)) (exposures)
CL Item
Necrotizing sarcoid granulomatosis (necrotizing)
CL Item
Histiocytic necrotizing lymphadenitis (Kikuchi´s disease) (histiocytic)
CL Item
Granulomatous Lesion of Unknown Significance (glus)
CL Item
Bronchocentric granulomatosis (bronchogranu)
Item
Lymphangioleiomyomatosis
integer
Code List
Lymphangioleiomyomatosis
Item
Thin walled cystic air spaces and patchy
integer
Code List
Thin walled cystic air spaces and patchy
Item
Spindle cells are located centrally with peripheral epithelioid cells
integer
Code List
Spindle cells are located centrally with peripheral epithelioid cells
Item
Cyst walls are lined by alveolar and bronchiolar epithelium
integer
Code List
Cyst walls are lined by alveolar and bronchiolar epithelium
Item
Resembles renal angiomyolipoma in that smooth muscle appears to spin off muscle coats of these structures
integer
Code List
Resembles renal angiomyolipoma in that smooth muscle appears to spin off muscle coats of these structures
Item
Muscle cells have optically clear cytoplasm
integer
Code List
Muscle cells have optically clear cytoplasm
Item
Hemosiderin pigment
integer
Code List
Hemosiderin pigment
Item
Pulmonary Alveolar Proteinosis
integer
Code List
Pulmonary Alveolar Proteinosis
Item
Alveoli contain amorphous
integer
Code List
Alveoli contain amorphous
Item
Variable fibrosis
integer
Code List
Variable fibrosis
Item
Mild / no lymphocytic infiltration
integer
Code List
Mild / no lymphocytic infiltration
Item
Characteristic cracking artefact
integer
Code List
Characteristic cracking artefact
Item
Macrophages and foreign body giant cells may be found around deposits
integer
Code List
Macrophages and foreign body giant cells may be found around deposits
Item
Labelling with Congo and immunohistochemistry
integer
Code List
Labelling with Congo and immunohistochemistry
Item
Eosinophilic disease
integer
Code List
Eosinophilic disease
CL Item
Acute eosinophilic pneumonia (known cause such as smoking and other inhalants, drugs or infections) or idiopathic (acuteeos)
CL Item
Chronic eosinophilic pneumonia (known causes such as drugs, infections, CV-ILD or idiopathic) (chroniceos)
CL Item
Loeffler's syndrome (known causes such as infections, especially parasites, drugs or idiopathic) (loefflerssynd)
CL Item
Predominant airway disease (as in asthma or allergic bronchopulmonary aspergillosis) (predominantair)
Item
ILD with lipid storage diseases (Niemann-Pick-disease, Gaucher disease)
integer
Code List
ILD with lipid storage diseases (Niemann-Pick-disease, Gaucher disease)
Item
Neurofibromatosis
integer
Code List
Neurofibromatosis
Item
Alveolar microlithiasis
integer
Code List
Alveolar microlithiasis
Item
Diffuse filling of alveolar air spaces by calcospherites
integer
Code List
Diffuse filling of alveolar air spaces by calcospherites
Item
Lamellated calcifications
integer
Code List
Lamellated calcifications
Item
Late stages may show increased localization to subpleural
integer
Code List
Late stages may show increased localization to subpleural
Item
Fibrosis and ossification may occur in same areas
integer
Code List
Fibrosis and ossification may occur in same areas
Item
Other vasculitides Please specify in comorbidities
integer
Code List
Other vasculitides Please specify in comorbidities