ClinSeq participants are being selected to represent the spectrum of atherosclerotic heart disease using the Framingham score (Wilson et al. 1998, PMID: 9603539) to balance accrual. The accrual target is three groups of 250 participants each who have a Framingham 10-yr coronary artery disease (CAD) risk of <5%, 5%-10%, and >10%, respectively, and an additional group of 250 participants who have a diagnosis of CAD based on a history of a myocardial infarction, coronary artery bypass graft surgery, stent placement, or other revascularization procedure. This accrual strategy was implemented so that the cohort would be enriched for detectable coronary atherosclerosis, as measured by computed tomography.
Item
ClinSeq participants are being selected to represent the spectrum of atherosclerotic heart disease using the Framingham score (Wilson et al. 1998, PMID: 9603539) to balance accrual. The accrual target is three groups of 250 participants each who have a Framingham 10-yr coronary artery disease (CAD) risk of <5%, 5%-10%, and >10%, respectively, and an additional group of 250 participants who have a diagnosis of CAD based on a history of a myocardial infarction, coronary artery bypass graft surgery, stent placement, or other revascularization procedure. This accrual strategy was implemented so that the cohort would be enriched for detectable coronary atherosclerosis, as measured by computed tomography.
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C0679646 (UMLS CUI [1,1])
C1882932 (UMLS CUI [1,2])
C2827424 (UMLS CUI [1,3])
C0010054 (UMLS CUI [1,4])
C5442395 (UMLS CUI [1,5])
C1510756 (UMLS CUI [1,6])
C0441833 (UMLS CUI [2,1])
C5442395 (UMLS CUI [2,2])
C1956346 (UMLS CUI [2,3])
C0011900 (UMLS CUI [2,4])
C0262926 (UMLS CUI [2,5])
C0027051 (UMLS CUI [2,6])
C4699471 (UMLS CUI [2,7])
C2348535 (UMLS CUI [2,8])
C5244011 (UMLS CUI [2,9])
C1510756 (UMLS CUI [3,1])
C0010054 (UMLS CUI [3,2])
C3830527 (UMLS CUI [3,3])
C0040405 (UMLS CUI [3,4])