Elig.phs001198.v1.p1.1
Item
*Inclusion Criteria:*
boolean
C1512693 (UMLS CUI [1,1])
Elig.phs001198.v1.p1.2
Item
*Age and Gender:* 21 to 50 years of age, both genders.
boolean
C0001779 (UMLS CUI [1,1])
C1706086 (UMLS CUI [1,2])
C0079399 (UMLS CUI [1,3])
Elig.phs001198.v1.p1.3
Item
*Handedness:* Right-handedness (score >20 on a modified Edinburgh Handedness Test).
boolean
C0205090 (UMLS CUI [1,1])
C0023114 (UMLS CUI [1,2])
C2737250 (UMLS CUI [1,3])
Elig.phs001198.v1.p1.4
Item
*Exclusion Criteria:*
boolean
C0680251 (UMLS CUI [1,1])
Elig.phs001198.v1.p1.5
Item
*Psychiatric disease:* Current Axis I diagnosis (according to DSM-IV criteria), except for the diagnosis of methamphetamine dependence (methamphetamine abuser group only) and nicotine dependence (both groups).
boolean
C0004936 (UMLS CUI [1,1])
C0270287 (UMLS CUI [1,2])
C1705847 (UMLS CUI [1,3])
C0025611 (UMLS CUI [1,4])
C0038580 (UMLS CUI [1,5])
C0028043 (UMLS CUI [1,6])
Elig.phs001198.v1.p1.6
Item
*History of Drug Abuse:* Potential participants with current dependence on any drug (other than nicotine, or for the methamphetamine group, methamphetamine) were excluded.
boolean
C1299544 (UMLS CUI [1,1])
C0521116 (UMLS CUI [1,2])
C0038580 (UMLS CUI [1,3])
C1705847 (UMLS CUI [1,4])
C0028043 (UMLS CUI [1,5])
C0002658 (UMLS CUI [1,6])
C0038580 (UMLS CUI [1,7])
Elig.phs001198.v1.p1.7
Item
*Medications:* Evidence of taking psychotropic medications (other than methamphetamine for the methamphetamine abuser group and nicotine for both groups) was exclusionary for both groups.
boolean
C0013227 (UMLS CUI [1,1])
C3887511 (UMLS CUI [1,2])
C1524063 (UMLS CUI [1,3])
C0033978 (UMLS CUI [1,4])
C1705847 (UMLS CUI [1,5])
C0025611 (UMLS CUI [1,6])
C0028040 (UMLS CUI [1,7])
Elig.phs001198.v1.p1.8
Item
*CNS Disease:* Structural brain abnormalities (e.g., neoplasms, subarachnoid cysts), cerebrovascular disease, infectious disease (e.g., abscess), history of other neurological disease, including stroke or head trauma (defined as loss of consciousness > 30 min or requiring hospitalization).
boolean
C0007682 (UMLS CUI [1,1])
C0851391 (UMLS CUI [1,2])
C0007820 (UMLS CUI [1,3])
C0009450 (UMLS CUI [1,4])
C0262926 (UMLS CUI [1,5])
C0018674 (UMLS CUI [1,6])
C0559159 (UMLS CUI [1,7])
Elig.phs001198.v1.p1.9
Item
*Cardiovascular Disease:* Advanced coronary artery disease, endocarditis or other cardiac disease likely to result in cerebral embolism.
boolean
C0007222 (UMLS CUI [1,1])
C0679246 (UMLS CUI [1,2])
C1956346 (UMLS CUI [1,3])
C0014118 (UMLS CUI [1,4])
C0205394 (UMLS CUI [1,5])
C0018799 (UMLS CUI [1,6])
C1444708 (UMLS CUI [1,7])
C1274040 (UMLS CUI [1,8])
C0007780 (UMLS CUI [1,9])
Elig.phs001198.v1.p1.10
Item
*Pulmonary Disease:* Significant obstructive pulmonary disease or tuberculosis.
boolean
C0024115 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0600260 (UMLS CUI [1,3])
C0041296 (UMLS CUI [1,4])
Elig.phs001198.v1.p1.11
Item
*Systemic Disease:* Endocrinopathies, renal or hepatic failure, or autoimmune disease involving the CNS.
boolean
C0442893 (UMLS CUI [1,1])
C0014130 (UMLS CUI [1,2])
C0035078 (UMLS CUI [1,3])
C0085605 (UMLS CUI [1,4])
C0004364 (UMLS CUI [1,5])
C0449389 (UMLS CUI [1,6])
Elig.phs001198.v1.p1.12
Item
*Claustrophobia:* Subjects were questioned about possible discomfort with being in an enclosed space (e.g., MRI scanner). Those who reported such problems were excluded.
boolean
C0008909 (UMLS CUI [1,1])
Elig.phs001198.v1.p1.13
Item
*Pregnancy:* Pregnancy, possible pregnancy, or failure to indicate the use of reliable birth control precautions. A pregnancy test was administered to each female participant before starting each of the 2 phases of the study. Subjects must have agreed to use an effective form of birth control between participation in Phase I and Phase II of the study. The only acceptable methods of birth control were: 1) oral contraceptive; 2) Depo-Provera injection; 3) intrauterine device; 4) diaphragm with contraceptive jelly; 5) condom with contraceptive jelly, foam, or sponge; 6) tubal ligation or hysterectomy; 7) abstinence from heterosexual intercourse.
boolean
C0032961 (UMLS CUI [1,1])
C0425965 (UMLS CUI [1,2])
C0680095 (UMLS CUI [1,3])
C1524063 (UMLS CUI [1,4])
C0700589 (UMLS CUI [1,5])
C0032976 (UMLS CUI [2,1])
C0332152 (UMLS CUI [2,2])
C2603343 (UMLS CUI [2,3])
C0205390 (UMLS CUI [2,4])
C1511481 (UMLS CUI [3,1])
C1524063 (UMLS CUI [3,2])
C0700589 (UMLS CUI [3,3])
C0489652 (UMLS CUI [3,4])
C1879533 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0009905 (UMLS CUI [4,3])
C3843416 (UMLS CUI [4,4])
C0021900 (UMLS CUI [4,5])
C0009653 (UMLS CUI [4,6])
C0020699 (UMLS CUI [4,7])
C0589114 (UMLS CUI [4,8])
C0004764 (UMLS CUI [4,9])
C0087145 (UMLS CUI [4,10])
C0036899 (UMLS CUI [4,11])
Elig.phs001198.v1.p1.14
Item
*HIV*: Subjects who were HIV-seropositive were excluded because HIV infection and the development of AIDS produces confounding alterations in brain activity that are dependent on the stage of AIDS.
boolean
C0019699 (UMLS CUI [1,1])
Elig.phs001198.v1.p1.15
Item
We excluded any subject whose body contained a ferromagnetic implanted device that might produce a safety hazard during fMRI. We used as guidelines, the manual, Magnetic Resonance: Bioeffects, Safety, and Patient Management45 supplemented by the current information published on the International MR Safety Web Site: http://kanal.arad.upmc.edu/mrsafety.html.
boolean
C3693688 (UMLS CUI [1,1])
C2911688 (UMLS CUI [1,2])
C0376335 (UMLS CUI [1,3])
Elig.phs001198.v1.p1.16
Item
*Vision:* Colorblindness, which could affect performance on the Stroop Task.
boolean
C0242225 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0597198 (UMLS CUI [1,3])
Elig.phs001198.v1.p1.17
Item
*Language:* Lack of fluency in English was exclusionary because it would interfere with performance of psychological tests and filling out questionnaires used in the study. The consent form, all questionnaires and instructions were administered in English.
boolean
C0332268 (UMLS CUI [1,1])
C0564215 (UMLS CUI [1,2])
C0586740 (UMLS CUI [1,3])
C0376245 (UMLS CUI [1,4])
C0521102 (UMLS CUI [1,5])
C0034394 (UMLS CUI [1,6])
C0033905 (UMLS CUI [1,7])
C1442085 (UMLS CUI [2,1])
C0021430 (UMLS CUI [2,2])
C0034394 (UMLS CUI [2,3])
C0376245 (UMLS CUI [2,4])