Elig.phs001208.v2.p1.1
Item
COGA recruited patients who were currently in a psychiatric inpatient or outpatient program for alcohol and/or chemical dependency. Detoxification must be complete before approaching the individual.
boolean
C0242800 (UMLS CUI [1,1])
C0521116 (UMLS CUI [1,2])
C0021562 (UMLS CUI [1,3])
C0029921 (UMLS CUI [1,4])
C1709762 (UMLS CUI [1,5])
C0085762 (UMLS CUI [1,6])
C0205394 (UMLS CUI [1,7])
C0038580 (UMLS CUI [1,8])
C0150543 (UMLS CUI [2,1])
C0205197 (UMLS CUI [2,2])
C0332152 (UMLS CUI [2,3])
C1516879 (UMLS CUI [2,4])
Elig.phs001208.v2.p1.2
Item
A potential proband: must not have used intravenous drugs more than 30 times lifetime and not within six months of screening, must not have any life-threatening illness other than alcohol-related terminal illnesses such as cirrhosis or Korsakoff's, must not be infected with the HIV virus, and his/her first-degree relatives must speak English, and live within one of the following six COGA catchment areas: Indiana, New York, St. Louis, Connecticut, Iowa, San Diego.
boolean
C3245505 (UMLS CUI [1,1])
C1948021 (UMLS CUI [1,2])
C1524063 (UMLS CUI [2,1])
C0086181 (UMLS CUI [2,2])
C0439092 (UMLS CUI [2,3])
C3816446 (UMLS CUI [2,4])
C0439546 (UMLS CUI [2,5])
C4071830 (UMLS CUI [2,6])
C1298908 (UMLS CUI [2,7])
C1524063 (UMLS CUI [2,8])
C0086181 (UMLS CUI [2,9])
C3828652 (UMLS CUI [2,10])
C0332152 (UMLS CUI [2,11])
C0220908 (UMLS CUI [2,12])
C1298908 (UMLS CUI [3,1])
C0205394 (UMLS CUI [3,2])
C3846017 (UMLS CUI [3,3])
C1298908 (UMLS CUI [4,1])
C0019693 (UMLS CUI [4,2])
C1517194 (UMLS CUI [5,1])
C0564215 (UMLS CUI [5,2])
C0376245 (UMLS CUI [5,3])
C2982691 (UMLS CUI [5,4])
C1524084 (UMLS CUI [5,5])
C0017446 (UMLS CUI [5,6])
Elig.phs001208.v2.p1.3
Item
Each COGA site recruited Control families consisting of two living parents and three or more full siblings, aged 14 or older. The Control Probands and families were ascertained via random consecutive sampling from either HMOs or dental clinics. They were to be representative of the general population and do not have to be unaffected individuals. Therefore, a Control family would not be eliminated if alcoholism is present among any of its members.
boolean
C0242800 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0015576 (UMLS CUI [1,3])
C0205448 (UMLS CUI [1,4])
C2584946 (UMLS CUI [1,5])
C0030551 (UMLS CUI [1,6])
C0205449 (UMLS CUI [1,7])
C0037047 (UMLS CUI [1,8])
C0439605 (UMLS CUI [2,1])
C1707491 (UMLS CUI [2,2])
C0870078 (UMLS CUI [2,3])
C0018720 (UMLS CUI [2,4])
C0011344 (UMLS CUI [2,5])
C1882932 (UMLS CUI [3,1])
C0683971 (UMLS CUI [3,2])
C1298908 (UMLS CUI [4,1])
C0680251 (UMLS CUI [4,2])
C0009932 (UMLS CUI [4,3])
C0086282 (UMLS CUI [4,4])
C0001973 (UMLS CUI [4,5])
Elig.phs001208.v2.p1.4
Item
We extend families through all affecteds, alive and dead, which means the standard protocol was administered to all first-degree relatives of all affecteds. If any of these relatives were affected, we extend to his/her first-degree relatives, and continue if any of them are affected. In addition, extension by leapfrogging over a living or dead unaffected into a branch containing at least two first-degree relatives of the "leapfrogee" who have 3 implications by history.
boolean
C2348563 (UMLS CUI [1,1])
C0231448 (UMLS CUI [1,2])
C0015576 (UMLS CUI [1,3])
C0522476 (UMLS CUI [1,4])
C1517194 (UMLS CUI [1,5])
C1517194 (UMLS CUI [2,1])
C0522476 (UMLS CUI [2,2])
C0231448 (UMLS CUI [2,3])
C1517194 (UMLS CUI [2,4])
C1524062 (UMLS CUI [3,1])
C3846158 (UMLS CUI [3,2])
C0522477 (UMLS CUI [3,3])
C1253959 (UMLS CUI [3,4])
C1148543 (UMLS CUI [3,5])
C0205448 (UMLS CUI [3,6])
C1517194 (UMLS CUI [3,7])
C0086282 (UMLS CUI [3,8])
C0262926 (UMLS CUI [3,9])
C0012634 (UMLS CUI [3,10])
C3146298 (UMLS CUI [3,11])