To be included in the T1DGC study, families, trios and case-control units had to meet specific criteria. For an affected sibling pair (ASP) family to be enrolled into the T1DGC, the family had to have at least one ASP available for sampling, with preference given to families with availability of one or both biological parents and at least one unaffected sibling. For trio families, both parents were necessary to include with the single T1D case. For cases, the individual had to be diagnosed with type 1 diabetes (T1D) with onset < 16 years and required use of insulin within 6 months of diagnosis with no concomitant disease or disorder associated with diabetes. The same diagnostic criteria hold for the case in trio families, and the proband in ASP families. In ASP families, the affected sibling could be included with onset < 35 years. For controls, the participant had no evidence of type 1 diabetes.
Item
To be included in the T1DGC study, families, trios and case-control units had to meet specific criteria. For an affected sibling pair (ASP) family to be enrolled into the T1DGC, the family had to have at least one ASP available for sampling, with preference given to families with availability of one or both biological parents and at least one unaffected sibling. For trio families, both parents were necessary to include with the single T1D case. For cases, the individual had to be diagnosed with type 1 diabetes (T1D) with onset < 16 years and required use of insulin within 6 months of diagnosis with no concomitant disease or disorder associated with diabetes. The same diagnostic criteria hold for the case in trio families, and the proband in ASP families. In ASP families, the affected sibling could be included with onset < 35 years. For controls, the participant had no evidence of type 1 diabetes.
boolean
C1512693 (UMLS CUI [1,1])
C0015576 (UMLS CUI [1,2])
C0007328 (UMLS CUI [1,3])
C0037047 (UMLS CUI [1,4])
C0392760 (UMLS CUI [1,5])
C3846158 (UMLS CUI [1,6])
C0870078 (UMLS CUI [1,7])
C0030551 (UMLS CUI [2,1])
C0011854 (UMLS CUI [2,2])
C0011854 (UMLS CUI [3,1])
C0001779 (UMLS CUI [3,2])
C1549444 (UMLS CUI [3,3])
C0243087 (UMLS CUI [3,4])
C0679228 (UMLS CUI [4,1])
C3846158 (UMLS CUI [4,2])
C0392760 (UMLS CUI [4,3])
C0037047 (UMLS CUI [4,4])
C0001779 (UMLS CUI [4,5])
C0009932 (UMLS CUI [5,1])
C0332125 (UMLS CUI [5,2])
C0011854 (UMLS CUI [5,3])