Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Case selection: 37 cases were accessed from the American College of Surgeons Oncology Group Z1041 trial (NCT00513292) that compared the pathological complete response (pCR) rate of patients with HER2-positive breast cancer who received a sequential regimen of concurrent weekly paclitaxel and trastuzumab followed by continued weekly trastuzumab administered concurrently with fluorouracil, epirubicin, and cyclophosphamide (FEC-75) to the pCR rate of a sequential regimen of FEC-75 alone followed by concurrent weekly paclitaxel and trastuzumab. An additional 11 HER2-positive included breast cancer cases were enrolled in a local trial at Washington University School of Medicine (NCT00353483) and received neoadjuvant treatment with trastuzumab in combination with other chemotherapies. All cases were females with invasive breast cancer, not pregnant, and >= 18 years of age. All cases were identified as HER2-positive by IHC and/or FISH.
Item
Case selection: 37 cases were accessed from the American College of Surgeons Oncology Group Z1041 trial (NCT00513292) that compared the pathological complete response (pCR) rate of patients with HER2-positive breast cancer who received a sequential regimen of concurrent weekly paclitaxel and trastuzumab followed by continued weekly trastuzumab administered concurrently with fluorouracil, epirubicin, and cyclophosphamide (FEC-75) to the pCR rate of a sequential regimen of FEC-75 alone followed by concurrent weekly paclitaxel and trastuzumab. An additional 11 HER2-positive included breast cancer cases were enrolled in a local trial at Washington University School of Medicine (NCT00353483) and received neoadjuvant treatment with trastuzumab in combination with other chemotherapies. All cases were females with invasive breast cancer, not pregnant, and >= 18 years of age. All cases were identified as HER2-positive by IHC and/or FISH.
boolean
C3669352 (UMLS CUI [1,1])
C0030761 (UMLS CUI [1,2])
C1706256 (UMLS CUI [1,3])
C1515944 (UMLS CUI [1,4])
C1579762 (UMLS CUI [1,5])
C4054230 (UMLS CUI [1,6])
C1960398 (UMLS CUI [1,7])
C0087111 (UMLS CUI [1,8])
C4522185 (UMLS CUI [1,9])
C0728747 (UMLS CUI [1,10])
C0060133 (UMLS CUI [1,11])
C4050242 (UMLS CUI [1,12])
C0020028 (UMLS CUI [1,13])
C1516879 (UMLS CUI [1,14])
C0600558 (UMLS CUI [1,15])
C1521750 (UMLS CUI [1,16])
C0086287 (UMLS CUI [1,17])
C0853879 (UMLS CUI [1,18])
C0232973 (UMLS CUI [1,19])
C0001779 (UMLS CUI [1,20])
C0021044 (UMLS CUI [1,21])
C0162789 (UMLS CUI [1,22])