English

The dataset includes data obtained with the HRSD and QIDS questionnaires at baseline and following 4- or 8-weeks of medication with citalopram or escitalopram, in addition to height/weight measures, and general socio-demographic information. Data of drug efficacy, remission/response to medication, and compliance with the medication protocol (subjects excluded when non-compliant) are included as well.

5 forms  
pht003556
Description

pht003556

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

SUBJID

Data type

text

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Race description
Description

lookup.race

Data type

string

Alias
UMLS CUI [1,1]
C0034510
Race code
Description

race

Data type

string

Alias
UMLS CUI [1,1]
C0034510
Gender
Description

gender

Data type

string

Alias
UMLS CUI [1,1]
C0079399
Age at Consent
Description

age

Data type

text

Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C0021430
QIDSC (Quick Inventory of Depressive Symptomatology) total score at Baseline
Description

qidsctotal.b

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C2964552
UMLS CUI [1,3]
C1442488
HRSD (Hamilton Rating Scale for Depression) total score at Baseline
Description

hrsdtotal.b

Data type

text

Alias
UMLS CUI [1,1]
C0451203
UMLS CUI [1,2]
C2964552
UMLS CUI [1,3]
C1442488
QIDSC total score at Week 4
Description

qidsctotal.w4

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C2964552
UMLS CUI [1,3]
C0439230
QIDSC remission status at Week 4 (Remitter if QIDSCTotal_W4 < =5, Non Remitter if QIDSCTotal_W4 > 5)
Description

remissionqids.w4

Data type

string

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0544452
UMLS CUI [1,3]
C0439230
(([QIDSCTotal_W4]-[QIDSCTotal_B])/[QIDSCTotal_B]*100)
Description

qidscpctchange.w4

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0439810
Responder if QIDSCpctChange_W4 > = 50 , Non Responder if QIDSCpctChange_W4 < 50
Description

qids.response2.w4

Data type

string

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C1704632
QIDSC total score at Week8
Description

qidsctotal.w8

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C2964552
UMLS CUI [1,3]
C0439230
QIDSC remission status at Week 8 (Remitter if QIDSCTotal_W8 < =5, Non Remitter if QIDSCTotal_W8 > 5)
Description

remissionqids.w8

Data type

string

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0544452
UMLS CUI [1,3]
C0439230
(([QIDSCTotal_W8]-[QIDSCTotal_B])/[QIDSCTotal_B]*100)
Description

qidscpctchange.w8

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0439810
Responder if QIDSCpctChange_W8 >= 50 , Non Responder if QIDSCpctChange_W8 < 50
Description

qids.response2.w8

Data type

string

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C1704632
Medication at Baseline (citalopram/escitalopram)
Description

med.b

Data type

string

Alias
UMLS CUI [1,1]
C0013227
UMLS CUI [1,2]
C1442488
UMLS CUI [1,3]
C0008845
UMLS CUI [1,4]
C1099456
Dose of med.b drug prescribed at Baseline
Description

dose.b

Data type

float

Measurement units
  • mg
Alias
UMLS CUI [1,1]
C0678766
UMLS CUI [1,2]
C3166216
UMLS CUI [1,3]
C1442488
mg
Dose of drug (citalopram/escitalopram) subject is taking on their Week 4 visit
Description

dose.w4

Data type

float

Measurement units
  • mg
Alias
UMLS CUI [1,1]
C0678766
UMLS CUI [1,2]
C1099456
UMLS CUI [1,3]
C0008845
UMLS CUI [1,4]
C0439230
mg
Dose of drug (citalopram/escitalopram) subject is taking on their Week 8 visit
Description

dose.w8

Data type

float

Measurement units
  • mg
Alias
UMLS CUI [1,1]
C0678766
UMLS CUI [1,2]
C0008845
UMLS CUI [1,3]
C1099456
UMLS CUI [1,4]
C0439230
mg
Baseline Height
Description

height

Data type

float

Measurement units
  • cm
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0005890
cm
Baseline Weight
Description

weight

Data type

float

Measurement units
  • kg
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0005910
kg
Marital status
Description

maritalstatus

Data type

string

Alias
UMLS CUI [1,1]
C0024819
Indicator of whether subject lives with spouse
Description

livewithspouse

Data type

text

Alias
UMLS CUI [1,1]
C2184147
Total number of years completed
Description

yearsschool

Data type

text

Alias
UMLS CUI [1,1]
C4288115
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C1556116
Highest degree completed
Description

highdegree

Data type

text

Alias
UMLS CUI [1,1]
C4264309
Is subject currently in school
Description

currentstudent

Data type

text

Alias
UMLS CUI [1,1]
C2136038
Current employment status
Description

currentempstat

Data type

text

Alias
UMLS CUI [1,1]
C0242271
Age at onset of first major depressive episode
Description

ageonset

Data type

text

Alias
UMLS CUI [1,1]
C0206132
UMLS CUI [1,2]
C0024517
UMLS CUI [1,3]
C0205435
Is there a seasonal pattern to your depression
Description

seasonalpattern

Data type

text

Alias
UMLS CUI [1,1]
C0085159
UMLS CUI [1,2]
C0011570
Are you currently involved in psychotherapy
Description

psychotherapy

Data type

text

Alias
UMLS CUI [1,1]
C0033968
UMLS CUI [1,2]
C0521116
Last visit remission defined as Remitter if last visit QIDS C <= 5, Non Remitter if last visit QIDSC > 5. If no W4 or W8 data then remission defined as Non Remitter.
Description

remission

Data type

string

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0544452
UMLS CUI [1,3]
C0545082
Last-visit response defined as Responder if QIDSCpctChange >=50 , Non Responder if QIDSCpctChange < 50. If no W4 or W8 data then response defined as Non Responder
Description

response

Data type

text

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C0545082
UMLS CUI [1,3]
C1704632
Difference between final visit QIDSC and baseline QIDSC, divided by baseline QIDSC and multiplied by 100. If no W4 or W8 data then change set to 0.
Description

qidscpctchange

Data type

float

Alias
UMLS CUI [1,1]
C4720917
UMLS CUI [1,2]
C1705241
UMLS CUI [1,3]
C5204638
UMLS CUI [1,4]
C5204632
Indicator of whether subject was excluded from GWAS
Description

IsExcluded

Data type

string

Alias
UMLS CUI [1,1]
C2350277
UMLS CUI [1,2]
C2828389
Non-Caucasian = Subject deemed non caucasian based on self-reported race and Structure Analyses Non-Compliant = Subject was deemed non compliant
Description

ExclusionReason

Data type

string

Alias
UMLS CUI [1,1]
C0034510
UMLS CUI [1,2]
C1518422
UMLS CUI [1,3]
C0007457
UMLS CUI [1,4]
C2700446
UMLS CUI [1,5]
C0936012
UMLS CUI [1,6]
C0457432
Month subject consented to study
Description

consentMonth

Data type

text

Alias
UMLS CUI [1,1]
C2711213
UMLS CUI [1,2]
C0439231
Year subject consented to study
Description

consentYear

Data type

text

Alias
UMLS CUI [1,1]
C2711213
UMLS CUI [1,2]
C0439234
Month of onset for current major depression episode
Description

currentonsetMonth

Data type

text

Alias
UMLS CUI [1,1]
C0439231
UMLS CUI [1,2]
C0332162
UMLS CUI [1,3]
C0521116
UMLS CUI [1,4]
C0024517
Year of onset for current major depression episode
Description

currentonsetYear

Data type

text

Alias
UMLS CUI [1,1]
C0439234
UMLS CUI [1,2]
C0332162
UMLS CUI [1,3]
C0521116
UMLS CUI [1,4]
C0024517
1st eigenvector from principal components analysis used as a covariate in adjusted GWAS
Description

EVEC.1

Data type

float

Alias
UMLS CUI [1,1]
C3846158
UMLS CUI [1,2]
C0429865
UMLS CUI [1,3]
C4684740
UMLS CUI [1,4]
C2350277
2nd eigenvector from principal components analysis used as a covariate in adjusted GWAS
Description

EVEC.2

Data type

float

Alias
UMLS CUI [1,1]
C3846158
UMLS CUI [1,2]
C0429865
UMLS CUI [1,3]
C4684740
UMLS CUI [1,4]
C2350277
3rd eigenvector from principal components analysis used as a covariate in adjusted GWAS
Description

EVEC.3

Data type

float

Alias
UMLS CUI [1,1]
C3846158
UMLS CUI [1,2]
C0429865
UMLS CUI [1,3]
C4684740
UMLS CUI [1,4]
C2350277
4th eigenvector from principal components analysis used as a covariate in adjusted GWAS
Description

EVEC.4

Data type

float

Alias
UMLS CUI [1,1]
C3846158
UMLS CUI [1,2]
C0429865
UMLS CUI [1,3]
C4684740
UMLS CUI [1,4]
C2350277
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Similar models

The dataset includes data obtained with the HRSD and QIDS questionnaires at baseline and following 4- or 8-weeks of medication with citalopram or escitalopram, in addition to height/weight measures, and general socio-demographic information. Data of drug efficacy, remission/response to medication, and compliance with the medication protocol (subjects excluded when non-compliant) are included as well.

5 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht003556
C3846158 (UMLS CUI [1,1])
SUBJID
Item
De-identified Subject ID
text
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
lookup.race
Item
Race description
string
C0034510 (UMLS CUI [1,1])
race
Item
Race code
string
C0034510 (UMLS CUI [1,1])
gender
Item
Gender
string
C0079399 (UMLS CUI [1,1])
age
Item
Age at Consent
text
C0001779 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
qidsctotal.b
Item
QIDSC (Quick Inventory of Depressive Symptomatology) total score at Baseline
text
C4720917 (UMLS CUI [1,1])
C2964552 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
hrsdtotal.b
Item
HRSD (Hamilton Rating Scale for Depression) total score at Baseline
text
C0451203 (UMLS CUI [1,1])
C2964552 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
qidsctotal.w4
Item
QIDSC total score at Week 4
text
C4720917 (UMLS CUI [1,1])
C2964552 (UMLS CUI [1,2])
C0439230 (UMLS CUI [1,3])
remissionqids.w4
Item
QIDSC remission status at Week 4 (Remitter if QIDSCTotal_W4 < =5, Non Remitter if QIDSCTotal_W4 > 5)
string
C4720917 (UMLS CUI [1,1])
C0544452 (UMLS CUI [1,2])
C0439230 (UMLS CUI [1,3])
qidscpctchange.w4
Item
(([QIDSCTotal_W4]-[QIDSCTotal_B])/[QIDSCTotal_B]*100)
text
C4720917 (UMLS CUI [1,1])
C0439810 (UMLS CUI [1,2])
qids.response2.w4
Item
Responder if QIDSCpctChange_W4 > = 50 , Non Responder if QIDSCpctChange_W4 < 50
string
C4720917 (UMLS CUI [1,1])
C1704632 (UMLS CUI [1,2])
qidsctotal.w8
Item
QIDSC total score at Week8
text
C4720917 (UMLS CUI [1,1])
C2964552 (UMLS CUI [1,2])
C0439230 (UMLS CUI [1,3])
remissionqids.w8
Item
QIDSC remission status at Week 8 (Remitter if QIDSCTotal_W8 < =5, Non Remitter if QIDSCTotal_W8 > 5)
string
C4720917 (UMLS CUI [1,1])
C0544452 (UMLS CUI [1,2])
C0439230 (UMLS CUI [1,3])
qidscpctchange.w8
Item
(([QIDSCTotal_W8]-[QIDSCTotal_B])/[QIDSCTotal_B]*100)
text
C4720917 (UMLS CUI [1,1])
C0439810 (UMLS CUI [1,2])
qids.response2.w8
Item
Responder if QIDSCpctChange_W8 >= 50 , Non Responder if QIDSCpctChange_W8 < 50
string
C4720917 (UMLS CUI [1,1])
C1704632 (UMLS CUI [1,2])
med.b
Item
Medication at Baseline (citalopram/escitalopram)
string
C0013227 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
C0008845 (UMLS CUI [1,3])
C1099456 (UMLS CUI [1,4])
dose.b
Item
Dose of med.b drug prescribed at Baseline
float
C0678766 (UMLS CUI [1,1])
C3166216 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
dose.w4
Item
Dose of drug (citalopram/escitalopram) subject is taking on their Week 4 visit
float
C0678766 (UMLS CUI [1,1])
C1099456 (UMLS CUI [1,2])
C0008845 (UMLS CUI [1,3])
C0439230 (UMLS CUI [1,4])
dose.w8
Item
Dose of drug (citalopram/escitalopram) subject is taking on their Week 8 visit
float
C0678766 (UMLS CUI [1,1])
C0008845 (UMLS CUI [1,2])
C1099456 (UMLS CUI [1,3])
C0439230 (UMLS CUI [1,4])
height
Item
Baseline Height
float
C1442488 (UMLS CUI [1,1])
C0005890 (UMLS CUI [1,2])
weight
Item
Baseline Weight
float
C1442488 (UMLS CUI [1,1])
C0005910 (UMLS CUI [1,2])
maritalstatus
Item
Marital status
string
C0024819 (UMLS CUI [1,1])
Item
Indicator of whether subject lives with spouse
text
C2184147 (UMLS CUI [1,1])
livewithspouse
Code List
Indicator of whether subject lives with spouse
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
yearsschool
Item
Total number of years completed
text
C4288115 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C1556116 (UMLS CUI [1,3])
Item
Highest degree completed
text
C4264309 (UMLS CUI [1,1])
highdegree
Code List
Highest degree completed
CL Item
None (1)
CL Item
GED (2)
CL Item
High School Diploma (3)
CL Item
Some College (4)
CL Item
Associates Degree/Technical Degree (5)
CL Item
College Diploma (6)
CL Item
Masters Degree (7)
CL Item
Doctorate or Professional Degree (e.g. MD, PhD, JD) (8)
Item
Is subject currently in school
text
C2136038 (UMLS CUI [1,1])
currentstudent
Code List
Is subject currently in school
CL Item
No (1)
CL Item
Full-time (2)
CL Item
Part-time (3)
Item
Current employment status
text
C0242271 (UMLS CUI [1,1])
currentempstat
Code List
Current employment status
CL Item
Unemployed,not looking (1)
CL Item
Unemployed, looking (2)
CL Item
Full-time employed (3)
CL Item
Part-time employed (4)
CL Item
Self-employed (5)
CL Item
Retired not working (6)
ageonset
Item
Age at onset of first major depressive episode
text
C0206132 (UMLS CUI [1,1])
C0024517 (UMLS CUI [1,2])
C0205435 (UMLS CUI [1,3])
Item
Is there a seasonal pattern to your depression
text
C0085159 (UMLS CUI [1,1])
C0011570 (UMLS CUI [1,2])
seasonalpattern
Code List
Is there a seasonal pattern to your depression
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Are you currently involved in psychotherapy
text
C0033968 (UMLS CUI [1,1])
C0521116 (UMLS CUI [1,2])
psychotherapy
Code List
Are you currently involved in psychotherapy
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
remission
Item
Last visit remission defined as Remitter if last visit QIDS C <= 5, Non Remitter if last visit QIDSC > 5. If no W4 or W8 data then remission defined as Non Remitter.
string
C4720917 (UMLS CUI [1,1])
C0544452 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])
Item
Last-visit response defined as Responder if QIDSCpctChange >=50 , Non Responder if QIDSCpctChange < 50. If no W4 or W8 data then response defined as Non Responder
text
C4720917 (UMLS CUI [1,1])
C0545082 (UMLS CUI [1,2])
C1704632 (UMLS CUI [1,3])
response
Code List
Last-visit response defined as Responder if QIDSCpctChange >=50 , Non Responder if QIDSCpctChange < 50. If no W4 or W8 data then response defined as Non Responder
CL Item
Non-Responder (Non-Responder)
CL Item
Responder (Responder)
qidscpctchange
Item
Difference between final visit QIDSC and baseline QIDSC, divided by baseline QIDSC and multiplied by 100. If no W4 or W8 data then change set to 0.
float
C4720917 (UMLS CUI [1,1])
C1705241 (UMLS CUI [1,2])
C5204638 (UMLS CUI [1,3])
C5204632 (UMLS CUI [1,4])
IsExcluded
Item
Indicator of whether subject was excluded from GWAS
string
C2350277 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
ExclusionReason
Item
Non-Caucasian = Subject deemed non caucasian based on self-reported race and Structure Analyses Non-Compliant = Subject was deemed non compliant
string
C0034510 (UMLS CUI [1,1])
C1518422 (UMLS CUI [1,2])
C0007457 (UMLS CUI [1,3])
C2700446 (UMLS CUI [1,4])
C0936012 (UMLS CUI [1,5])
C0457432 (UMLS CUI [1,6])
consentMonth
Item
Month subject consented to study
text
C2711213 (UMLS CUI [1,1])
C0439231 (UMLS CUI [1,2])
consentYear
Item
Year subject consented to study
text
C2711213 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
currentonsetMonth
Item
Month of onset for current major depression episode
text
C0439231 (UMLS CUI [1,1])
C0332162 (UMLS CUI [1,2])
C0521116 (UMLS CUI [1,3])
C0024517 (UMLS CUI [1,4])
currentonsetYear
Item
Year of onset for current major depression episode
text
C0439234 (UMLS CUI [1,1])
C0332162 (UMLS CUI [1,2])
C0521116 (UMLS CUI [1,3])
C0024517 (UMLS CUI [1,4])
EVEC.1
Item
1st eigenvector from principal components analysis used as a covariate in adjusted GWAS
float
C3846158 (UMLS CUI [1,1])
C0429865 (UMLS CUI [1,2])
C4684740 (UMLS CUI [1,3])
C2350277 (UMLS CUI [1,4])
EVEC.2
Item
2nd eigenvector from principal components analysis used as a covariate in adjusted GWAS
float
C3846158 (UMLS CUI [1,1])
C0429865 (UMLS CUI [1,2])
C4684740 (UMLS CUI [1,3])
C2350277 (UMLS CUI [1,4])
EVEC.3
Item
3rd eigenvector from principal components analysis used as a covariate in adjusted GWAS
float
C3846158 (UMLS CUI [1,1])
C0429865 (UMLS CUI [1,2])
C4684740 (UMLS CUI [1,3])
C2350277 (UMLS CUI [1,4])
EVEC.4
Item
4th eigenvector from principal components analysis used as a covariate in adjusted GWAS
float
C3846158 (UMLS CUI [1,1])
C0429865 (UMLS CUI [1,2])
C4684740 (UMLS CUI [1,3])
C2350277 (UMLS CUI [1,4])
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