All selected subjects are normal according to following criteria
Item
All selected subjects are normal according to following criteria:
boolean
C1512693 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
C0460094 (UMLS CUI [1,3])
Subjects with chromosomal or large-scale genomic abnormalities, detected by karyogram and/or Illumina Human Omni-2.5, were excluded.
Item
Subjects with chromosomal or large-scale genomic abnormalities, detected by karyogram and/or Illumina Human Omni-2.5, were excluded.
boolean
C0680251 (UMLS CUI [1,1])
C0008625 (UMLS CUI [1,2])
C1704258 (UMLS CUI [1,3])
C0887950 (UMLS CUI [1,4])
Prenatal and neonatal specimens were excluded if drug or alcohol abuse by the mother during pregnancy was reported or if potassium chloride, salt water, or urea were injected into the amniotic sac during surgical procedure
Item
Prenatal and neonatal specimens were excluded if drug or alcohol abuse by the mother during pregnancy was reported or if potassium chloride, salt water, or urea were injected into the amniotic sac during surgical procedure.
boolean
C0680251 (UMLS CUI [1,1])
C0370003 (UMLS CUI [1,2])
C0678804 (UMLS CUI [1,3])
C2939425 (UMLS CUI [1,4])
C0013146 (UMLS CUI [1,5])
C0001948 (UMLS CUI [1,6])
C0026591 (UMLS CUI [1,7])
C0347984 (UMLS CUI [1,8])
C0032961 (UMLS CUI [1,9])
C0680251 (UMLS CUI [2,1])
C0370003 (UMLS CUI [2,2])
C0678804 (UMLS CUI [2,3])
C2939425 (UMLS CUI [2,4])
C1272883 (UMLS CUI [2,5])
C0883994 (UMLS CUI [2,6])
C0032825 (UMLS CUI [2,7])
C0036082 (UMLS CUI [2,8])
C0041942 (UMLS CUI [2,9])
C0347984 (UMLS CUI [2,10])
C0543467 (UMLS CUI [2,11])
Only brains free of obvious malformations or lesions were collected.
Item
Only brains free of obvious malformations or lesions were collected. Disqualifying characteristics included any obvious abnormality of the neural tube, forebrain, brainstem, cranial nerves, cerebellum, or spinal cord.
boolean
C0680251 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C3714787 (UMLS CUI [1,3])
Samples were excluded if microscopic analysis revealed extensive neuronal loss, neuronal swelling, glioneuronal heterotopias, or dysmorphic neurons and neurites.
Item
Samples were excluded if microscopic analysis revealed extensive neuronal loss, neuronal swelling, glioneuronal heterotopias, or dysmorphic neurons and neurites.
boolean
C0680251 (UMLS CUI [1,1])
C2678195 (UMLS CUI [1,2])
C3670503 (UMLS CUI [1,3])
C0266491 (UMLS CUI [1,4])
C5194942 (UMLS CUI [1,5])
C0432072 (UMLS CUI [1,6])
C0085103 (UMLS CUI [1,7])
Samples that tested positive for Hepatitis B, Hepatitis C, or HIV were excluded.
Item
Samples that tested positive for Hepatitis B, Hepatitis C, or HIV were excluded.
boolean
C0680251 (UMLS CUI [1,1])
C0019693 (UMLS CUI [1,2])
C0019163 (UMLS CUI [1,3])
C0019196 (UMLS CUI [1,4])
Early postnatal and adult (periods 8-15) specimens were excluded if excessive drug or alcohol abuse was reported, if the individual had any known neurological or psychiatric disorders, or if any prolonged agonal conditions were reported.
Item
Early postnatal and adult (periods 8-15) specimens were excluded if excessive drug or alcohol abuse was reported, if the individual had any known neurological or psychiatric disorders, or if any prolonged agonal conditions were reported.
boolean
C0680251 (UMLS CUI [1,1])
C0038586 (UMLS CUI [1,2])
C0004936 (UMLS CUI [1,3])
C0027765 (UMLS CUI [1,4])
C0262926 (UMLS CUI [1,5])
C0439590 (UMLS CUI [1,6])
C0030193 (UMLS CUI [1,7])