Elig.phs000391.v1.p1.1
Item
Inclusion Criteria:
boolean
C1512693 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.2
Item
Of Old Order Amish descent
boolean
C0238622 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.3
Item
At least 20 years old
boolean
C4323877 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.4
Item
Exclusion Criteria:
boolean
C0680251 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.5
Item
Currently pregnant or less than 6 months have passed since delivery
boolean
C0549206 (UMLS CUI [1,1])
C0439092 (UMLS CUI [2,1])
C4082120 (UMLS CUI [2,2])
C0086839 (UMLS CUI [2,3])
Elig.phs000391.v1.p1.6
Item
History of a bleeding disorder or major spontaneous bleed, such as peptic ulcer, epistasis, or intracranial bleed
boolean
C0005779 (UMLS CUI [1,1])
C1321132 (UMLS CUI [2,1])
Elig.phs000391.v1.p1.7
Item
Severe hypertension, defined by a blood pressure above 160/95 mm Hg, making it unethical not to recommend prompt treatment
boolean
C4013784 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.8
Item
Medications that would affect the outcome(s) to be measured and cannot willingly and safely, in the opinion of the treating physician and study physician, discontinue these medications for 1 week prior to protocol initiation
boolean
C4717992 (UMLS CUI [1,1])
C1319171 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
C93407 (UMLS CUI [1,4])
Elig.phs000391.v1.p1.9
Item
Vitamins or other supplements and is unwilling to discontinue their use for at least 1 week prior to study
boolean
C0242295 (UMLS CUI [1,1])
C1548265 (UMLS CUI [1,2])
Elig.phs000391.v1.p1.10
Item
Coexisting malignancy
boolean
C4482549 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
Elig.phs000391.v1.p1.11
Item
Creatinine level greater than 2.0 mg/dl, aspartate transaminase (AST) or alanine transaminase (ALT) greater than two times the upper limit of normal, hematocrit less than 32%, or a thyroid-stimulating hormone (TSH) less than 0.4 or greater than 5.5 mIU/L
boolean
C5557309 (UMLS CUI [1,1])
C0580476 (UMLS CUI [2,1])
C0151905 (UMLS CUI [3,1])
C1295607 (UMLS CUI [4,1])
C0586553 (UMLS CUI [5,1])
Elig.phs000391.v1.p1.12
Item
Bleeding disorder or history of gastrointestinal bleeding or other major bleeding episode
boolean
C0005779 (UMLS CUI [1,1])
C0262926 (UMLS CUI [2,1])
C0017181 (UMLS CUI [2,2])
C0262926 (UMLS CUI [3,1])
C0019080 (UMLS CUI [3,2])
Elig.phs000391.v1.p1.13
Item
Currently taking aspirin, clopidogrel, or other anti-coagulant, such as warfarin, heparin, or GPIIb/IIIa antagonists, and have conditions that might place them at increased risk from withdrawal of these medications 14 days prior to protocol initiation, including history of unstable angina, heart attack, angioplasty (including stent placement), coronary artery bypass surgery, atrial fibrillation, stroke or transient ischemic attacks, diabetes, or deep vein thrombosis or other thrombosis
boolean
C0150457 (UMLS CUI [1,1])
C0558681 (UMLS CUI [1,2])
C5545962 (UMLS CUI [1,3])
Elig.phs000391.v1.p1.14
Item
Polycythemia, or thrombocytosis, defined by a platelet count greater than 500,000
boolean
C0032461 (UMLS CUI [1,1])
C0836924 (UMLS CUI [2,1])
Elig.phs000391.v1.p1.15
Item
Thrombocytopenia, defined by a platelet count less than 75,000
boolean
C0040034 (UMLS CUI [1,1])
Elig.phs000391.v1.p1.16
Item
Surgery within the last 6 months
boolean
C0744961 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C4082120 (UMLS CUI [1,3])
Elig.phs000391.v1.p1.17
Item
Aspirin or clopidogrel allergy
boolean
C0004058 (UMLS CUI [1,1])
C1689910 (UMLS CUI [2,1])
Elig.phs000391.v1.p1.18
Item
Currently breast feeding
boolean
C0006147 (UMLS CUI [1,1])