Ausschlusskriterien
Previous treatment with VELCADE
boolean
More than 3 previous lines of therapy (separate lines of therapy are defined as single or combination therapies that are either separated by disease progression or by a greater than 6 month treatment-free interval)
boolean
Peripheral neuropathy or neuropathic pain of NCI CTCAE Grade ≥2
boolean
Any of the following within 3 weeks prior to randomization:
boolean
antineoplastic or experimental therapy, corticosteroid use above 10mg a day (prednisone or equivalent), or plasmapheresis
boolean
Any of the following within 2 weeks prior to randomization:
boolean
radiation therapy, major surgery (kyphoplasty is not considered major surgery)
boolean
Prior malignancy other than multiple myeloma diagnosed or treated within the last 2 years, with the exception of completely resected carcinoma in situ or basal/squamous carcinoma of the skin
boolean