Liver carcinoma
Item
1. diagnosis of hcc confirmed by histology or non-invasive criteria (easl/aasld)
boolean
C2239176 (UMLS CUI [1])
Liver carcinoma BCLC Stage | Liver carcinoma Large | Liver carcinoma Multinodular | Liver carcinoma Child-Pugh Classification | performance status
Item
2. intermediate stage (bclc-b) hcc: patients with a large or multinodular hcc (single hcc > 5 cm or multiple hcc defined as > 3 nodules > 3 cm), a child pugh class a or b7 and no cancer related symptoms (ps=0-1).
boolean
C2239176 (UMLS CUI [1,1])
C3898888 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2,1])
C0549177 (UMLS CUI [2,2])
C2239176 (UMLS CUI [3,1])
C0205416 (UMLS CUI [3,2])
C2239176 (UMLS CUI [4,1])
C4050412 (UMLS CUI [4,2])
C1518965 (UMLS CUI [5])
Liver carcinoma BCLC Stage | Hepatic Involvement vascular | Liver carcinoma Child-Pugh Classification | performance status | Tumor Extrahepatic Spread Absent
Item
3. advanced stage (bclc-c) hcc: patients with hepatic vascular involvement (at any tumor number and diameter), a child pugh class a or b7, no cancer related symptoms (ps=0-1) and absence of extra-hepatic tumor spread.
boolean
C2239176 (UMLS CUI [1,1])
C3898888 (UMLS CUI [1,2])
C0441932 (UMLS CUI [2,1])
C0005847 (UMLS CUI [2,2])
C2239176 (UMLS CUI [3,1])
C4050412 (UMLS CUI [3,2])
C1518965 (UMLS CUI [4])
C0027651 (UMLS CUI [5,1])
C1517058 (UMLS CUI [5,2])
C0332261 (UMLS CUI [5,3])
C0332197 (UMLS CUI [5,4])
Symptoms Malignant Neoplasm Related ECOG performance status
Item
4. cancer-related symptoms within the ecog 0-1 score
boolean
C1457887 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0439849 (UMLS CUI [1,3])
C1520224 (UMLS CUI [1,4])
Liver function Child-Pugh Classification
Item
5. liver function within child b-7 class
boolean
C0232741 (UMLS CUI [1,1])
C4050412 (UMLS CUI [1,2])
Platelet Count measurement
Item
6. platelets > 50.000/µl
boolean
C0032181 (UMLS CUI [1])
White Blood Cell Count procedure
Item
7. wbc > 1500/µl
boolean
C0023508 (UMLS CUI [1])
Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
8. ast/alt < 5 times the upper limit of normal (u/l)
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
Creatinine measurement, serum
Item
9. creatinine < 2.0 mg /dl
boolean
C0201976 (UMLS CUI [1])
Indication Absent Curative treatment | Multidisciplinary assessment | Excision | Ablation | Transplantation
Item
10. no indication for any possible curative treatment after multidisciplinary assessment (resection, ablation, transplantation)
boolean
C3146298 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1273390 (UMLS CUI [1,3])
C0729737 (UMLS CUI [2])
C0728940 (UMLS CUI [3])
C0547070 (UMLS CUI [4])
C0040732 (UMLS CUI [5])
Informed Consent
Item
11. signed informed consent
boolean
C0021430 (UMLS CUI [1])
Child-Pugh Classification
Item
1. child-pugh class higher than b-7 at entry
boolean
C4050412 (UMLS CUI [1])
ECOG performance status
Item
2. ecog performance score ≥ 2 at entry
boolean
C1520224 (UMLS CUI [1])
Tumor Volume % volume Liver
Item
3. tumor volume ≥ 50% of liver volume
boolean
C0475276 (UMLS CUI [1,1])
C1690016 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
Tumor Extrahepatic Spread
Item
4. extrahepatic tumor spread
boolean
C0027651 (UMLS CUI [1,1])
C1517058 (UMLS CUI [1,2])
C0332261 (UMLS CUI [1,3])
lung; insufficiency
Item
5. pulmonary insufficiency
boolean
C1401064 (UMLS CUI [1])
Life Expectancy Due to Liver carcinoma | Life Expectancy Due to Disease
Item
6. life expectancy of less than 3 months due to hcc or less than 6 months due to any other disease
boolean
C0023671 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C2239176 (UMLS CUI [1,3])
C0023671 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0012634 (UMLS CUI [2,3])
Chemoembolization | Transarterial Chemoembolization
Item
7. previous chemoembolization procedure (tace)
boolean
C0796679 (UMLS CUI [1])
C3539919 (UMLS CUI [2])
Vascular shunt Tc-99m MAA Scan | Embolization coil Angiography Unsuccessful
Item
8. evidence on 99mtc-maa scan of vascular shunts that can not be corrected by angiographic coil embolization
boolean
C0232350 (UMLS CUI [1,1])
C0039415 (UMLS CUI [1,2])
C0441633 (UMLS CUI [1,3])
C0522644 (UMLS CUI [2,1])
C0002978 (UMLS CUI [2,2])
C1272705 (UMLS CUI [2,3])
Lung shunting Tc-99m MAA Scan | Radiation absorbed dose Lung
Item
9. evidence on 99mtc-maa scan of lung shunting, with a potential absorbed dose of radiation to the lungs > 30 gy
boolean
C0024109 (UMLS CUI [1,1])
C0813207 (UMLS CUI [1,2])
C0039415 (UMLS CUI [1,3])
C0441633 (UMLS CUI [1,4])
C0556643 (UMLS CUI [2,1])
C0024109 (UMLS CUI [2,2])