Gender | Age | Breast Carcinoma unresectable | Unwilling Mastectomy Glandular
Item
1. women 18 years or older with unresectable breast cancer, not amenable/willing to adenomammectomy.
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0678222 (UMLS CUI [3,1])
C1519810 (UMLS CUI [3,2])
C0558080 (UMLS CUI [4,1])
C0024881 (UMLS CUI [4,2])
C0225353 (UMLS CUI [4,3])
Breast Carcinoma | Core needle biopsy of breast
Item
2. breast carcinoma diagnosed by core needle biopsy.
boolean
C0678222 (UMLS CUI [1])
C0191853 (UMLS CUI [2])
Menopausal Status
Item
3. any menopausal status.
boolean
C3829127 (UMLS CUI [1])
En Bloc Surgical biopsy | Lumpectomy (breast cancer) | Diagnosis | Therapeutic procedure | Breast Carcinoma
Item
4. no history of en bloc open surgical biopsy and/or lumpectomy for diagnostic/treatment of the index breast cancer.
boolean
C1516835 (UMLS CUI [1,1])
C0565118 (UMLS CUI [1,2])
C0740370 (UMLS CUI [2])
C0011900 (UMLS CUI [3])
C0087111 (UMLS CUI [4])
C0678222 (UMLS CUI [5])
Tumor size | Mammography | Ultrasonics (sound) | Magnetic Resonance Imaging
Item
5. tumor size ≤ 5.0 cm in greatest diameter. largest size measured by required scans (mammogram, ultrasound and mri) will be used to determine eligibility.
boolean
C0475440 (UMLS CUI [1])
C0024671 (UMLS CUI [2])
C1456803 (UMLS CUI [3])
C0024485 (UMLS CUI [4])
Neoplasms Enhancement | Magnetic Resonance Imaging Pre-study
Item
6. tumor enhancement on pre-study mri.
boolean
C0027651 (UMLS CUI [1,1])
C2349975 (UMLS CUI [1,2])
C0024485 (UMLS CUI [2,1])
C1527048 (UMLS CUI [2,2])
Intraductal breast neoplasm
Item
7. tumor with < 25% intraductal components in the aggregate.
boolean
C0948967 (UMLS CUI [1])
Tumor Progression | Adjuvant therapy | Advanced breast cancer | Carcinoma breast stage IV | Breast Cancer Therapeutic Procedure
Item
8. progressed within 12 months from prior adjuvant or progressed within 1 month from prior advanced/metastatic endocrine breast cancer therapy,
boolean
C0178874 (UMLS CUI [1])
C0677850 (UMLS CUI [2])
C3495917 (UMLS CUI [3])
C0278488 (UMLS CUI [4])
C1511300 (UMLS CUI [5])
Pregnancy | Breast Feeding | Childbearing Potential | Serum pregnancy test negative | Urine pregnancy test negative
Item
9. non-pregnant and non-lactating. patients of childbearing potential must have a negative serum or urine pregnancy test.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3])
C0430061 (UMLS CUI [4])
C0430057 (UMLS CUI [5])
Breast size | Irreversible electroporation system | Carcinoma of Male Breast | Female Breast Carcinoma | Breast Prosthesis, Internal
Item
10. adequate breast size for safe ire. male breast cancer patients and female breast cancer patients with breasts too small to allow safe ire are not eligible as the minimal thickness of the breast tissue does not lend itself to ire. note: for patients with breast implants, the treating physician must document that adequate distance exists between the lesion and the implant to ensure that the ablated lesion will not contact or jeopardize the implant.
boolean
C0425782 (UMLS CUI [1])
C3876171 (UMLS CUI [2])
C0238033 (UMLS CUI [3])
C0007104 (UMLS CUI [4])
C0179412 (UMLS CUI [5])
body system or organ function | Bone Marrow Function | Toxic effect | Prior Therapy | history of prior surgery
Item
11. adequate organ and marrow function, resolution of all toxic effects of prior therapy or surgical procedures
boolean
C0678852 (UMLS CUI [1])
C0005953 (UMLS CUI [2,1])
C0542341 (UMLS CUI [2,2])
C0600688 (UMLS CUI [3])
C1514463 (UMLS CUI [4])
C0744961 (UMLS CUI [5])
Tumor tissue sample
Item
12. patient must agree to provide tumor tissue from metastatic tissue at baseline.
boolean
C0475358 (UMLS CUI [1])
Multifocal breast carcinoma | Multicentric Breast Carcinoma | Calcification of breast | Noninfiltrating Intraductal Carcinoma
Item
1. patients with multifocal and/or multicentric ipsilateral breast cancer, multifocal calcifications, or evidence of excessive dcis.
boolean
C2986662 (UMLS CUI [1])
C2986664 (UMLS CUI [2])
C0587094 (UMLS CUI [3])
C0007124 (UMLS CUI [4])
Vacuum-Assisted Biopsy | En Bloc Surgical biopsy | Lumpectomy (breast cancer) | Diagnosis | Therapeutic procedure | Breast Carcinoma
Item
2. history of rotational vacuum assisted core biopsies, en bloc open surgical biopsy and/or lumpectomy for diagnosis/treatment of the index breast cancer.
boolean
C1710607 (UMLS CUI [1])
C1516835 (UMLS CUI [2,1])
C0565118 (UMLS CUI [2,2])
C0740370 (UMLS CUI [3])
C0011900 (UMLS CUI [4])
C0087111 (UMLS CUI [5])
C0678222 (UMLS CUI [6])
Neoadjuvant Therapy Chemotherapy Regimen Breast Carcinoma
Item
3. prior or planned neoadjuvant chemotherapy for breast cancer.
boolean
C0600558 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0678222 (UMLS CUI [1,3])
Thrombocytopenia | Abnormality of coagulation
Item
4. patients with thrombocytopenia and or any other coagulation abnormality
boolean
C0040034 (UMLS CUI [1])
C1846821 (UMLS CUI [2])