Ausschlusskriterien
Patients with significantly impaired bone marrow function or significant anemia, leukopenia, or thrombocytopenia
boolean
Persistent significant or severe infection
boolean
Liver function impairment or known history of hepatitis
boolean
Use of adrenocorticotrophic hormone (ACTH) or systemic corticosteroids for 2 weeks prior to randomization
boolean
Human immunodeficiency virus (HIV) positive patients
boolean
Prior use of Rebif, or prior or concomitant use of other interferons in the 3 months prior to randomization
boolean
Prior or concomitant use of cladribine, mitoxantrone, or other immunosuppressant agents such as azathioprine, cyclophosphamide, cyclosporin, methotrexate, mycophenolate, or natalizumab
boolean
Pregnant or breast-feeding women
boolean