Age
Item
1. all patients must be greater than 18 years of age
boolean
C0001779 (UMLS CUI [1])
Left Ventricular Function Reduced | Heart failure | Cardiac ejection fraction
Item
2. patients with reduced left ventricular function (i.e., heart failure patients) must have acquired heart failure and an ejection fraction less than 35% documented in the last two years by any methodology
boolean
C0080310 (UMLS CUI [1,1])
C0392756 (UMLS CUI [1,2])
C0018801 (UMLS CUI [2])
C0232174 (UMLS CUI [3])
Control Group | Free of Heart failure Symptoms | Free of Diastolic dysfunction | Free of Left ventricular systolic dysfunction
Item
3. control population patients must be free of heart failure symptoms, diastolic dysfunction, and left ventricular systolic dysfunction documented by any methodology within 1 year of study enrollment
boolean
C0009932 (UMLS CUI [1])
C0332296 (UMLS CUI [2,1])
C0018801 (UMLS CUI [2,2])
C1457887 (UMLS CUI [2,3])
C0332296 (UMLS CUI [3,1])
C0520863 (UMLS CUI [3,2])
C0332296 (UMLS CUI [4,1])
C1277187 (UMLS CUI [4,2])
ICD Duration | ICD Events
Item
4. patients with an icd in place for more than 1 year and evidence of icd events
boolean
C0162589 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C0162589 (UMLS CUI [2,1])
C0441471 (UMLS CUI [2,2])
ICD Duration | ICD Events Absent
Item
5. patients with an icd in place for more than 1 year and no evidence of icd events
boolean
C0162589 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C0162589 (UMLS CUI [2,1])
C0441471 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Informed Consent
Item
6. all patients must be able to give informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
1. patients less than 18 years of age.
boolean
C0001779 (UMLS CUI [1])
Impaired left ventricular function caused by Congenital heart disease
Item
2. history of congenital heart disease as cause of impaired left ventricular function.
boolean
C0242698 (UMLS CUI [1,1])
C0015127 (UMLS CUI [1,2])
C0152021 (UMLS CUI [1,3])
Control Group | LEFT VENTRICULAR FUNCTION SYSTOLIC DYSFUNCTION | Diastolic dysfunction
Item
3. control patients with impaired left ventricular systolic function or the presence of diastolic dysfunction.
boolean
C0009932 (UMLS CUI [1])
C0745679 (UMLS CUI [2])
C0520863 (UMLS CUI [3])
Control Group | Study Subject | Long QT Syndrome | Brugada Syndrome
Item
4. control or study group patients with a history of congenital electrophysiological disorders like the long-qt syndrome or brugada disease will not be included.
boolean
C0009932 (UMLS CUI [1])
C0681850 (UMLS CUI [2])
C0023976 (UMLS CUI [3])
C1142166 (UMLS CUI [4])
Control Group | Study Subject | Requirement Anti-Arrhythmia Agents | Other Coding
Item
5. control or study group patients who require antiarrhythmic drugs other than vaughn-williams class ii and iv agents.
boolean
C0009932 (UMLS CUI [1])
C0681850 (UMLS CUI [2])
C1514873 (UMLS CUI [3,1])
C0003195 (UMLS CUI [3,2])
C3846158 (UMLS CUI [4])
Control Group | Illness Impairing Cardiac function | Myocardial Infarction | Hospitalization Due to Cardiac problem | Cardiac Arrhythmia | Communicable Disease | Malignant Neoplasm
Item
6. control patients with a history of significant illness that may otherwise impair cardiac function within 12 months of study enrollment. these conditions include: myocardial infarction, cardiac hospitalization, cardiac arrhythmia, infection, or cancer.
boolean
C0009932 (UMLS CUI [1])
C0221423 (UMLS CUI [2,1])
C0221099 (UMLS CUI [2,2])
C0232164 (UMLS CUI [2,3])
C0027051 (UMLS CUI [3])
C0019993 (UMLS CUI [4,1])
C0678226 (UMLS CUI [4,2])
C0262402 (UMLS CUI [4,3])
C0003811 (UMLS CUI [5])
C0009450 (UMLS CUI [6])
C0006826 (UMLS CUI [7])
ICD Patients | Terminal illness | Chronic inflammatory disorder
Item
7. icd patients suffering from any other terminal or chronic inflammatory illness.
boolean
C0162589 (UMLS CUI [1,1])
C0030705 (UMLS CUI [1,2])
C0679247 (UMLS CUI [2])
C1290886 (UMLS CUI [3])
Immunosuppressive Agents | Chronic infectious disease | Inflammatory disorder | Chronic inflammatory disorder
Item
8. patients taking immunosuppressive medications, have chronic infection, or have an acute or chronic inflammatory illness that might alter white cell mrna expression.
boolean
C0021081 (UMLS CUI [1])
C0151317 (UMLS CUI [2])
C1290884 (UMLS CUI [3])
C1290886 (UMLS CUI [4])
Illness Resulting in Death
Item
9. patients with any illness expected to result in death within 18 months of enrollment.
boolean
C0221423 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0011065 (UMLS CUI [1,3])
White blood cell Dyscrasia | White blood cell Cancer
Item
10. patients with white blood cell dyscrasia or cancers.
boolean
C0023516 (UMLS CUI [1,1])
C0334044 (UMLS CUI [1,2])
C0023516 (UMLS CUI [2,1])
C0006826 (UMLS CUI [2,2])
Illicit medication use
Item
11. current illicit drug use.
boolean
C0281875 (UMLS CUI [1])
Informed Consent Unable
Item
12. inability to give informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])