Gender
Item
men and women
boolean
C0079399 (UMLS CUI [1])
Age
Item
at least 35 years of age
boolean
C0001779 (UMLS CUI [1])
Osteoarthritis Mild | Symptoms Arthritis of knee | Kellgren-Lawrence score
Item
mild oa patients with arthritic knee symptoms and kl score of 1-2
boolean
C0029408 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C1457887 (UMLS CUI [2,1])
C0240111 (UMLS CUI [2,2])
C3177117 (UMLS CUI [3])
Osteoarthritis Severe | Symptoms Arthritis of knee | Kellgren-Lawrence score
Item
severe oa patients with arthritic knee symptoms and kl score of 3-4
boolean
C0029408 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1457887 (UMLS CUI [2,1])
C0240111 (UMLS CUI [2,2])
C3177117 (UMLS CUI [3])
Symptoms Knee Osteoarthritis | Pain days per month | Aching days per month | Stiffness days per month | Pharmacotherapy Knee pain
Item
knee symptoms in oa patients is defined as pain, aching, or stiffness on most days of a month during the past year or use of medication for treatment of knee pain on most days of a month during the past year
boolean
C1457887 (UMLS CUI [1,1])
C0409959 (UMLS CUI [1,2])
C0030193 (UMLS CUI [2,1])
C0556971 (UMLS CUI [2,2])
C0234238 (UMLS CUI [3,1])
C0556971 (UMLS CUI [3,2])
C0427008 (UMLS CUI [4,1])
C0556971 (UMLS CUI [4,2])
C0013216 (UMLS CUI [5,1])
C0231749 (UMLS CUI [5,2])
Knee pain Medial compartment days per week | Age | Morning stiffness Duration | Crepitus During Motion | Knee joint tender | Bony joint enlargement Knee | Synovium Warmth Lacking
Item
self reported knee pain (defined as medial compartment knee pain at least 1 day per week during each of the 6 weeks prior to participation) and at least 3 of the following 6 clinical indicators: age>50 years; morning stiffness<30 minutes duration; crepitus on active motion; tenderness of the bony margins of the knee joint; bony enlargement at the knee; and lack of palpable warmth of the synovium
boolean
C0231749 (UMLS CUI [1,1])
C0447799 (UMLS CUI [1,2])
C0677547 (UMLS CUI [1,3])
C0001779 (UMLS CUI [2])
C0457086 (UMLS CUI [3,1])
C0449238 (UMLS CUI [3,2])
C0277964 (UMLS CUI [4,1])
C0347984 (UMLS CUI [4,2])
C0026597 (UMLS CUI [4,3])
C0576134 (UMLS CUI [5])
C0221610 (UMLS CUI [6,1])
C0022742 (UMLS CUI [6,2])
C0039099 (UMLS CUI [7,1])
C0392197 (UMLS CUI [7,2])
C0332268 (UMLS CUI [7,3])
Investigational New Drugs
Item
current use of investigational drug
boolean
C0013230 (UMLS CUI [1])
Condition Limiting Lower Extremity Function | Exception Osteoarthritis | Condition Limiting Lower Extremity Mobility | Condition Interferes with Evaluation Function | Degeneration Disc spinal | Painful feet | Foot Dysfunction | Peripheral Vascular Disease | Lumbar radiculopathy | Trochanteric bursitis | Hip pain | Lumbar Pain
Item
conditions other than oa which limit lower extremity function and mobility and/or would confound the evaluation of function (e.g., clinically significant spinal disc degeneration, painful or dysfunctional feet, peripheral vascular disease, lumbar radiculopathy, trochanteric bursitis, hip pain, lumbar pain)
boolean
C0348080 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0023216 (UMLS CUI [1,3])
C0031843 (UMLS CUI [1,4])
C1705847 (UMLS CUI [2,1])
C0029408 (UMLS CUI [2,2])
C0348080 (UMLS CUI [3,1])
C0439801 (UMLS CUI [3,2])
C0023216 (UMLS CUI [3,3])
C0080078 (UMLS CUI [3,4])
C0348080 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C1261322 (UMLS CUI [4,3])
C0031843 (UMLS CUI [4,4])
C0011164 (UMLS CUI [5,1])
C1556138 (UMLS CUI [5,2])
C0521329 (UMLS CUI [5,3])
C0857248 (UMLS CUI [6])
C1704557 (UMLS CUI [7])
C0085096 (UMLS CUI [8])
C1263855 (UMLS CUI [9])
C0151451 (UMLS CUI [10])
C0019559 (UMLS CUI [11])
C0024031 (UMLS CUI [12])
Metal foreign body in eye region | Vascular clip | Pacemakers | Medical contraindication MRI
Item
patients with metallic fragments in the eyes, vascular clips, pacemakers, and other contraindications to mri
boolean
C0562528 (UMLS CUI [1])
C0179992 (UMLS CUI [2])
C0810633 (UMLS CUI [3])
C1301624 (UMLS CUI [4,1])
C0024485 (UMLS CUI [4,2])
Joint Replacement | Fracture Intra-articular | Osteotomy Knee Affected | Arthroplasty Knee Affected | Meniscectomy Knee Affected
Item
history of joint replacement, intra-articular fracture, osteotomy, arthroplasty or meniscectomy of the signal knee
boolean
C0185317 (UMLS CUI [1])
C0016658 (UMLS CUI [2,1])
C0442108 (UMLS CUI [2,2])
C0029468 (UMLS CUI [3,1])
C0022742 (UMLS CUI [3,2])
C0392760 (UMLS CUI [3,3])
C0003893 (UMLS CUI [4,1])
C0022742 (UMLS CUI [4,2])
C0392760 (UMLS CUI [4,3])
C0187901 (UMLS CUI [5,1])
C0022742 (UMLS CUI [5,2])
C0392760 (UMLS CUI [5,3])
Other medical condition Involving Target Joint | Inflammatory disorder Systemic | Crystal Arthropathy | Knee infection | Avascular necrosis | Paget's disease | Neoplasms
Item
history of other disease that may involve the study joint including systemic inflammatory disease, crystalline disease, knee infection of the signal knee, avascular necrosis, paget's disease or tumors
boolean
C3843040 (UMLS CUI [1,1])
C1314939 (UMLS CUI [1,2])
C1521840 (UMLS CUI [1,3])
C0022417 (UMLS CUI [1,4])
C1290884 (UMLS CUI [2,1])
C0205373 (UMLS CUI [2,2])
C0152087 (UMLS CUI [3])
C1400580 (UMLS CUI [4])
C3887513 (UMLS CUI [5])
C0029401 (UMLS CUI [6])
C0027651 (UMLS CUI [7])
Heart condition Limiting Activities of Daily Living
Item
self reported heart condition that limits any daily physical activity
boolean
C3842523 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0001288 (UMLS CUI [1,3])
Pregnancy
Item
patients who are pregnant
boolean
C0032961 (UMLS CUI [1])