Age | Hypertensive disease | Antihypertensive Agents Quantity | Diuretics Quantity
Item
men and women 18 to 65 years of age with hypertension, treated with three or more anti-hypertensive drugs, one being a diuretic, and
boolean
C0001779 (UMLS CUI [1])
C0020538 (UMLS CUI [2])
C0003364 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0012798 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
Systolic Pressure Clinic | Systolic Pressure Daytime Average Ambulatory Blood Pressure Monitoring
Item
having a systolic blood pressure >150 mmhg in the clinic and daytime average >150 mmhg on ambulatory blood pressure monitoring
boolean
C0871470 (UMLS CUI [1,1])
C0442592 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2,1])
C0332169 (UMLS CUI [2,2])
C1510992 (UMLS CUI [2,3])
C0242876 (UMLS CUI [2,4])
Secondary hypertension | Obesity Severe | Body mass index | Mental Disorders, Severe | Malignant Neoplasms | Exception Skin carcinoma | Herpes zoster disease | Cytomegalovirus Resolved Recent
Item
medical history of secondary cause of hypertension, severe obesity (bmi >35), severe psychiatric disorders, cancer in the last 5 years other than nonmelanoma skin cell cancers, herpes zoster or cytomegalovirus that resolved less than 2 months before
boolean
C0155616 (UMLS CUI [1])
C0028754 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C1305855 (UMLS CUI [3])
C4046029 (UMLS CUI [4])
C0006826 (UMLS CUI [5])
C1705847 (UMLS CUI [6,1])
C0699893 (UMLS CUI [6,2])
C0019360 (UMLS CUI [7])
C0010825 (UMLS CUI [8,1])
C1514893 (UMLS CUI [8,2])
C0332185 (UMLS CUI [8,3])
Abatacept therapy Continue Unable | Follow-up Continue Unable
Item
inability to return for abatacept treatment and follow-up for 24 weeks.
boolean
C4302766 (UMLS CUI [1,1])
C0549178 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C3274571 (UMLS CUI [2,1])
C0549178 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
Evaluation Comprehension Unable | Completion Evaluation Unable
Item
inability to understand or complete study-related assessments.
boolean
C1261322 (UMLS CUI [1,1])
C0162340 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C0205197 (UMLS CUI [2,1])
C1261322 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
Substance Use Disorders
Item
current abuse of drugs or alcohol.
boolean
C0038586 (UMLS CUI [1])
Vaccines, Attenuated
Item
receipt of any live vaccines within 3 months of the anticipated first dose of study medication.
boolean
C0042211 (UMLS CUI [1])
Bacterial Infections | Latent bacterial disease | Virus Diseases | Latent virus infection | HIV Infection | HIV Infection Latent
Item
evidence of active or latent bacterial or viral infections at the time of potential enrollment, including human immunodeficiency virus (hiv)
boolean
C0004623 (UMLS CUI [1])
C0596823 (UMLS CUI [2])
C0042769 (UMLS CUI [3])
C0596824 (UMLS CUI [4])
C0019693 (UMLS CUI [5])
C0019693 (UMLS CUI [6,1])
C0205275 (UMLS CUI [6,2])
At risk Tuberculosis
Item
risk for tuberculosis
boolean
C1444641 (UMLS CUI [1,1])
C0041296 (UMLS CUI [1,2])
Laboratory test result abnormal | Hepatitis B surface antigen positive | Hemoglobin measurement | White Blood Cell Count procedure | Platelet Count measurement | Serum creatinine raised | Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
abnormal laboratory values including positive hepatitis b surface antigen, hemoglobin < 8.5 g/dl, white blood cell count < 3000/mm3, platelets < 100,000/mm3, creatinine > 2.5 times the upper limit of normal (uln), alanine aminotransferase or aspartate aminotransferase > 2 times the uln.
boolean
C0438215 (UMLS CUI [1])
C0149709 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
C0023508 (UMLS CUI [4])
C0032181 (UMLS CUI [5])
C0700225 (UMLS CUI [6])
C0151905 (UMLS CUI [7])
C0151904 (UMLS CUI [8])