Hypertensive disease Untreated | Age
Item
never-treated hypertensive subjects, aged 20-80 years (at the time of informed consent), regardless of sex
boolean
C0020538 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
Sitting systolic blood pressure | Sitting diastolic blood pressure
Item
clinic systolic bp/diastolic bp > 140/90 mmhg in a sitting position.
boolean
C1319893 (UMLS CUI [1])
C1319894 (UMLS CUI [2])
Medical contraindication Adrenergic beta-1 Receptor Antagonists | Asthma | Chronic Obstructive Airway Disease
Item
beta−blocker contraindications(asthma, copd…)
boolean
C1301624 (UMLS CUI [1,1])
C0304516 (UMLS CUI [1,2])
C0004096 (UMLS CUI [2])
C0024117 (UMLS CUI [3])
Heart rate
Item
heart rate less than 55 bpm
boolean
C0018810 (UMLS CUI [1])
Nitrates
Item
subjects treated with nitrates
boolean
C0028125 (UMLS CUI [1])
Hypertensive disease Grade | Blood pressure determination
Item
grade 3 hypertension (≥180 and/or ≥110 mmhg)
boolean
C0020538 (UMLS CUI [1,1])
C0441800 (UMLS CUI [1,2])
C0005824 (UMLS CUI [2])
Secondary hypertension | Malignant Hypertension
Item
secondary hypertension or malignant hypertension
boolean
C0155616 (UMLS CUI [1])
C0020540 (UMLS CUI [2])
Heart failure | Coronary Artery Disease | Cerebrovascular accident
Item
history of heart failure, coronary artery disease, and stroke
boolean
C0018801 (UMLS CUI [1])
C1956346 (UMLS CUI [2])
C0038454 (UMLS CUI [3])
Cardiac Arrhythmia
Item
arrhythmia
boolean
C0003811 (UMLS CUI [1])
Renal dysfunction | Creatinine measurement, serum
Item
renal dysfunction (serum creatinine ≥2.0 mg/dl)
boolean
C3279454 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Liver Dysfunction | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
hepatic dysfunction (ast and/or alt ≥100 iu/l)
boolean
C0086565 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
Malignant Neoplasms | Suspected malignancy
Item
a history of or a suspected malignant tumor within 5 years of enrollment
boolean
C0006826 (UMLS CUI [1])
C0581833 (UMLS CUI [2])
Chronic inflammatory disorder
Item
chronic inflammatory disease
boolean
C1290886 (UMLS CUI [1])
Pregnancy | Childbearing Potential Contraceptive methods Inadequate | Breast Feeding
Item
pregnancy, childbearing potential with inadequate contraception, breast feeding
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0205412 (UMLS CUI [2,3])
C0006147 (UMLS CUI [3])
Informed Consent Unable
Item
inability to give informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])