Hypertension, moderate | Hypertension, severe
Item
moderate to severe hypertension
boolean
C1969581 (UMLS CUI [1])
C4013784 (UMLS CUI [2])
Risk factors Additional Quantity | Age | Gender | Tobacco use | Diabetes Mellitus, Non-Insulin-Dependent | Obesity | Cardiovascular Disease | Congestive heart failure | Chronic Kidney Disease
Item
3 additional risk factors such as age > 55 (male), > 65 female, smoker, type 2 diabetes, obesity, cardiovascular disease, congestive heart failure, chronic kidney disease,
boolean
C0035648 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0001779 (UMLS CUI [2])
C0079399 (UMLS CUI [3])
C0543414 (UMLS CUI [4])
C0011860 (UMLS CUI [5])
C0028754 (UMLS CUI [6])
C0007222 (UMLS CUI [7])
C0018802 (UMLS CUI [8])
C1561643 (UMLS CUI [9])
Informed Consent
Item
ability to give informed consent
boolean
C0021430 (UMLS CUI [1])
Secondary hypertension | Malignant Hypertension
Item
secondary or malignant hypertension
boolean
C0155616 (UMLS CUI [1])
C0020540 (UMLS CUI [2])
Medical contraindication Investigational New Drugs
Item
contraindication to any of the study drugs
boolean
C1301624 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
Creatinine clearance measurement
Item
creatinine clearance level <40ml/min
boolean
C0373595 (UMLS CUI [1])
Antihypertensive Agents Quantity
Item
treatment with more than 3 antihypertensive drugs
boolean
C0003364 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Myocardial Infarction | Percutaneous Transluminal Coronary Angioplasty | Coronary Artery Bypass Surgery
Item
myocardial infarction, percutaneous transluminal coronary angioplasty, cardiac bypass surgery < 6 month prior to start of the study,
boolean
C0027051 (UMLS CUI [1])
C2936173 (UMLS CUI [2])
C0010055 (UMLS CUI [3])
Angina, Unstable
Item
unstable angina pectoris,
boolean
C0002965 (UMLS CUI [1])
Cerebrovascular accident | Transient Ischemic Attack
Item
stroke, transient ischemic attack < 3 months prior to start,
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
Congestive heart failure New York Heart Association Classification
Item
congestive heart failure nyha ii-iv,
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Comorbidity Relevance Clinical
Item
clinically relevant concomitant diseases,
boolean
C0009488 (UMLS CUI [1,1])
C2347946 (UMLS CUI [1,2])
C0205210 (UMLS CUI [1,3])
Substance Use Disorders
Item
alcohol or drug abuse,
boolean
C0038586 (UMLS CUI [1])
Pregnancy | Childbearing Potential Contraceptive methods Absent
Item
pregnancy or women of childbearing potential without contraceptive precaution,
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])