Hepatitis C, Chronic | Hepatitis C Antibodies Positive | Hepatitis C virus RNA Detected
Item
1. chronic hepatitis c infection, diagnosed by positive anti-hcv antibodies and detected hcv rna at screening
boolean
C0524910 (UMLS CUI [1])
C0166049 (UMLS CUI [2,1])
C1514241 (UMLS CUI [2,2])
C0369335 (UMLS CUI [3,1])
C0442726 (UMLS CUI [3,2])
Hepatitis C Genotype | Hepatitis virus genotyping
Item
2. hcv infection of sub-gt1b confirmed by genotypic testing at screening.
boolean
C0019196 (UMLS CUI [1,1])
C1533728 (UMLS CUI [1,2])
C2368162 (UMLS CUI [2])
HCV viral load
Item
3. hcv viral load =1,000 iu/ml at randomisation.
boolean
C1868902 (UMLS CUI [1])
Prior Therapy Absent Hepatitis C
Item
4. patients who have never been previously treated with any other hcv treatment regimen.
boolean
C1514463 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0019196 (UMLS CUI [1,3])
Hepatitis C Genotype Mixed | Hepatitis virus genotyping
Item
1. hcv infection of mixed gt (1/2, 1/3, and 1/4) diagnosed by genotypic testing at screening.
boolean
C0019196 (UMLS CUI [1,1])
C1533728 (UMLS CUI [1,2])
C0205430 (UMLS CUI [1,3])
C2368162 (UMLS CUI [2])
Hepatitis C Genotype | Hepatitis C Genotype Mixed | Hepatitis C Genotype undefined
Item
2. hcv infection of sub-gt1a, mixed gt1a/1b, or undefined gt1.
boolean
C0019196 (UMLS CUI [1,1])
C1533728 (UMLS CUI [1,2])
C0019196 (UMLS CUI [2,1])
C1533728 (UMLS CUI [2,2])
C0205430 (UMLS CUI [2,3])
C0019196 (UMLS CUI [3,1])
C1533728 (UMLS CUI [3,2])
C0750600 (UMLS CUI [3,3])
Liver disease | Etiology Except Chronic Hepatitis C
Item
3. liver disease due to causes other than chronic hcv infection.
boolean
C0023895 (UMLS CUI [1])
C0015127 (UMLS CUI [2,1])
C0332300 (UMLS CUI [2,2])
C0524910 (UMLS CUI [2,3])
HIV Infection
Item
4. hiv infection.
boolean
C0019693 (UMLS CUI [1])
Hepatitis B | Hepatitis B Surface Antigens Present
Item
5. hepatitis b virus infection based on presence of hbs-ag.
boolean
C0019163 (UMLS CUI [1])
C0019168 (UMLS CUI [2,1])
C0150312 (UMLS CUI [2,2])
Malignant Neoplasms | Malignant Neoplasm Suspected
Item
6. confirmed or suspected active malignancy or history of malignancy within the last 5 years prior to screening.
boolean
C0006826 (UMLS CUI [1])
C0006826 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
DRUG ABUSE ILLICIT | Exception Marihuana | Alcoholic Intoxication, Chronic
Item
7. history of illicit drug abuse other than cannabis or chronic alcohol abuse within 12 months prior to randomisation.
boolean
C0743253 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0024808 (UMLS CUI [2,2])
C0001973 (UMLS CUI [3])
Compliance Unwilling Precautionary procedure | Precautionary procedure Preventing Photosensitivity
Item
8. subject is not willing to comply with the precautionary measures to prevent photosensitivity (avoid excessive sun exposure and use sun block on a daily basis).
boolean
C1321605 (UMLS CUI [1,1])
C0558080 (UMLS CUI [1,2])
C1300317 (UMLS CUI [1,3])
C1300317 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C0349506 (UMLS CUI [2,3])
Decompensated liver disease
Item
9. decompensated liver disease, or history of decompensated liver disease.
boolean
C4075847 (UMLS CUI [1])
Cardiovascular Disease Unstable
Item
10. clinical evidence of unstable cardiovascular disease which may further decompensate due to anemia.
boolean
C0007222 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
Disease Erythrocytic
Item
11. red blood cell disorders.
boolean
C0012634 (UMLS CUI [1,1])
C0014792 (UMLS CUI [1,2])
Body Weight
Item
12. body weight <40 kg or >125 kg.
boolean
C0005910 (UMLS CUI [1])