Age
Item
adult patients, >/= 18 years of age
boolean
C0001779 (UMLS CUI [1])
moderate to severe active rheumatoid arthritis, disease activity, DAS28
Item
moderate to severe active rheumatoid arthritis, defined as DAS28 >/= 3.7
boolean
C2368567 (UMLS CUI [1])
C0003873 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C4481729 (UMLS CUI [3])
Clinical response to DMARD + Methotrexate or Anti-TNF therapy, inadequate
Item
inadequate clinical response to current treatment with >/= 2 non-biologic dmards, 1 of them being methotrexate optimally administered for >/= 3 months, or inadequate clinical response to anti-tnf therapy
boolean
C0242708 (UMLS CUI [1,1])
C0332257 (UMLS CUI [1,2])
C0025677 (UMLS CUI [1,3])
C1704632 (UMLS CUI [1,4])
C0205412 (UMLS CUI [1,5])
C0281481 (UMLS CUI [2,1])
C1704632 (UMLS CUI [2,2])
C0205412 (UMLS CUI [2,3])
Eligible Roactemra, Eligible Actemra
Item
eligible for roactemra/actemra treatment in daily clinical practice
boolean
C1548635 (UMLS CUI [1,1])
C3272237 (UMLS CUI [1,2])
C1548635 (UMLS CUI [2,1])
C2740854 (UMLS CUI [2,2])
Tuberculosis, Absent
Item
absence of evolutive tuberculosis (tb)
boolean
C0041296 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Hypersensitivity, Tocilicumab or other excipients
Item
hypersensitivity to tocilizumab or any of the excipients
boolean
C0020517 (UMLS CUI [1,1])
C1609165 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0015237 (UMLS CUI [2,2])
Active Infections
Item
active, severe infections
boolean
C0009450 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Pregnant, lactating
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Study Participation, Interventional Study
Item
participation in any other interventional study
boolean
C2348568 (UMLS CUI [1,1])
C3274035 (UMLS CUI [1,2])
Depression
Item
patients with major depression
boolean
C1269683 (UMLS CUI [1])