Ischemic cardiomyopathy | Cardiomyopathy, Dilated | Age
Item
patients with ischaemic or dilated cardiomyopathy aged 18 to 80 years.
boolean
C0349782 (UMLS CUI [1])
C0007193 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Symptoms Level | Therapy Optimal | Inpatient | Disease Management At home | Dependence Hospital care
Item
symptoms categorised by intermacs (interagency registry for mechanically assisted circulatory support) at level 3-6 despite optimal tolerated medical therapy. practically this includes patients who are in hospital or managing at home with substantial dependence on hospital care.
boolean
C1457887 (UMLS CUI [1,1])
C0441889 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C2698651 (UMLS CUI [2,2])
C0021562 (UMLS CUI [3])
C0376636 (UMLS CUI [4,1])
C4534363 (UMLS CUI [4,2])
C0439857 (UMLS CUI [5,1])
C0259945 (UMLS CUI [5,2])
Peak Oxygen consumption measurement | Respiratory Exchange Ratio Cardiopulmonary Exercise Test | 6-Minute Walk Test Distance | Exercise test Unable | Etiology Heart failure Severe
Item
peak vo2 <15ml/kg/min with respiratory exchange ratio>1 on cardiopulmonary exercise testing or a 6-minute walking distance <300m or inability to perform an exercise test due to the severity of heart failure.
boolean
C0444505 (UMLS CUI [1,1])
C1305742 (UMLS CUI [1,2])
C4049826 (UMLS CUI [2,1])
C2959886 (UMLS CUI [2,2])
C0430515 (UMLS CUI [3,1])
C0012751 (UMLS CUI [3,2])
C0015260 (UMLS CUI [4,1])
C1299582 (UMLS CUI [4,2])
C0015127 (UMLS CUI [5,1])
C0018801 (UMLS CUI [5,2])
C0205082 (UMLS CUI [5,3])
Informed Consent
Item
informed consent obtained prior to entering the study.
boolean
C0021430 (UMLS CUI [1])
Etiology Heart failure | Thyroid Disease uncorrected | Hypertrophic Cardiomyopathy | Disorder of pericardium | Amyloidosis | Myocarditis
Item
cause of heart failure due to or associated with uncorrected thyroid disease, obstructive cardiomyopathy, pericardial disease, amyloidosis, or active myocarditis
boolean
C0015127 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
C0040128 (UMLS CUI [2,1])
C4072785 (UMLS CUI [2,2])
C0007194 (UMLS CUI [3])
C0265122 (UMLS CUI [4])
C0002726 (UMLS CUI [5])
C0027059 (UMLS CUI [6])
Body Surface Area | Body mass index
Item
body surface area <1.2m2 or >2.3m2, or body mass index >32 kg/m2.
boolean
C0005902 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
Severe chronic obstructive pulmonary disease | Percent predicted FEV1
Item
severe chronic obstructive pulmonary disease as evidenced by forced expiratory volume in 1 second <50% of predicted.
boolean
C0730607 (UMLS CUI [1])
C0730561 (UMLS CUI [2])
Pulmonary Hypertension | Pulmonary Vascular Resistance Wood units | Gradient Transpulmonary
Item
history of pulmonary hypertension with maintained pulmonary vascular resistance measured > 4 wood units or transpulmonary gradient >14mmhg.
boolean
C0020542 (UMLS CUI [1])
C0456261 (UMLS CUI [2,1])
C0439525 (UMLS CUI [2,2])
C0812409 (UMLS CUI [3,1])
C0442377 (UMLS CUI [3,2])
Pregnancy
Item
pregnancy.
boolean
C0032961 (UMLS CUI [1])
Liver disease intrinsic | Elevated liver enzymes level | Liver Dysfunction Severe | Liver Cirrhosis Severe | Portal Hypertension Severe
Item
evidence of intrinsic hepatic disease defined as liver enzyme levels > 5 times the upper limit of normal within 4 days before enrolment, severe liver dysfunction, cirrhosis or portal hypertension.
boolean
C0023895 (UMLS CUI [1,1])
C0205102 (UMLS CUI [1,2])
C0857093 (UMLS CUI [2])
C0086565 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0023890 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0020541 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
Cerebrovascular accident
Item
occurrence of stroke within 90 days before enrolment.
boolean
C0038454 (UMLS CUI [1])
Impaired cognition | Dementia
Item
impairment of cognitive function or presence of any form of irreversible dementia.
boolean
C0338656 (UMLS CUI [1])
C0497327 (UMLS CUI [2])
Mental disorders Impairing Protocol Compliance | Substance Use Disorders Impairing Protocol Compliance
Item
recent history of psychiatric disease (including severe drug or alcohol abuse) that is likely to impair compliance with the study protocol.
boolean
C0004936 (UMLS CUI [1,1])
C0221099 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C0038586 (UMLS CUI [2,1])
C0221099 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
Platelet Count measurement
Item
platelet count <50 x103mm3 within 24 hours before enrolment.
boolean
C0032181 (UMLS CUI [1])
Creatinine clearance measurement
Item
creatinine clearance < 30ml/min.
boolean
C0373595 (UMLS CUI [1])
Compliance behavior Unlikely
Item
high probability of non-compliance.
boolean
C1321605 (UMLS CUI [1,1])
C0750558 (UMLS CUI [1,2])
Study Subject Participation Status Unsuitable for other reasons
Item
the patient is deemed unsuitable by the clinical team for other reasons.
boolean
C2348568 (UMLS CUI [1,1])
C3844399 (UMLS CUI [1,2])