Age
Item
men and women aged 18 years and older. the lower age limit may be higher if legally required in the participating country
boolean
C0001779 (UMLS CUI [1])
Childbearing Potential Pregnancy test negative | Childbearing Potential Sexually active Contraceptive methods
Item
women of childbearing potential can only be included in the study if a pregnancy test is negative and if they agree to use adequate contraception when sexually active
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0241028 (UMLS CUI [2,2])
C0700589 (UMLS CUI [2,3])
Chronic heart failure Worsening | Requirement Emergency hospital admission | Requirement Diuretics Intravenous
Item
subjects with worsening chronic heart failure requiring emergency presentation to hospital and treatment with intravenous diuretics at hospital
boolean
C0264716 (UMLS CUI [1,1])
C0332271 (UMLS CUI [1,2])
C1514873 (UMLS CUI [2,1])
C0184673 (UMLS CUI [2,2])
C1514873 (UMLS CUI [3,1])
C0012798 (UMLS CUI [3,2])
C1522726 (UMLS CUI [3,3])
Chronic heart failure Ischemic New York Heart Association Classification | Chronic heart failure New York Heart Association Classification
Item
subjects with clinical diagnosis of chronic heart failure (chf) either ischemic or non ischemic, new york heart association (nyha) functional class ii-iv
boolean
C0264716 (UMLS CUI [1,1])
C0475224 (UMLS CUI [1,2])
C1275491 (UMLS CUI [1,3])
C0264716 (UMLS CUI [2,1])
C1275491 (UMLS CUI [2,2])
Diabetes Mellitus, Non-Insulin-Dependent
Item
subjects with type 2 diabetes mellitus and / or
boolean
C0011860 (UMLS CUI [1])
eGFR | eGFR MDRD Clinical trial group
Item
subjects with 30 ml/min/1.73m2 </= egfr </= 60 ml/min/1.73m2 (mdrd, modification of diet in renal disease study group) at screening
boolean
C3811844 (UMLS CUI [1])
C3811844 (UMLS CUI [2,1])
C3839656 (UMLS CUI [2,2])
C1320290 (UMLS CUI [2,3])
Left ventricular ejection fraction
Item
left ventricular ejection fraction (lvef) </= 40%
boolean
C0428772 (UMLS CUI [1])
Blood potassium measurement
Item
blood potassium </= 5.0 mmol/l at screening
boolean
C0729816 (UMLS CUI [1])
Systolic Pressure | Absence Signs and Symptoms Hypotension
Item
systolic blood pressure >/= 90 mmhg without signs and symptoms of hypotension at the screening visit
boolean
C0871470 (UMLS CUI [1])
C0332197 (UMLS CUI [2,1])
C0037088 (UMLS CUI [2,2])
C0020649 (UMLS CUI [2,3])
Heart failure de novo | Heart Disease inflammatory | Myocarditis
Item
acute de-novo heart failure or acute inflammatory heart disease, e.g. acute myocarditis
boolean
C0018801 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C0018799 (UMLS CUI [2,1])
C0333348 (UMLS CUI [2,2])
C0027059 (UMLS CUI [3])
Acute Coronary Syndrome
Item
acute coronary syndrome (acs) in last 30 days prior to screening
boolean
C0948089 (UMLS CUI [1])
Shock, Cardiogenic
Item
cardiogenic shock
boolean
C0036980 (UMLS CUI [1])
Heart valve disease Requirement Surgical intervention
Item
valvular heart disease requiring surgical intervention during the course of the study
boolean
C0018824 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0549433 (UMLS CUI [1,3])
Cerebrovascular accident | Transient Ischemic Attack
Item
stroke or transient ischemic cerebral attack in the last 3 months prior to the screening visit
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
Mineralocorticoid Receptor Antagonists | Renin inhibitor | Potassium Sparing Diuretics
Item
concomitant treatment with any mineralocorticoid receptor antagonist (mra), renin inhibitor, or potassium-sparing diuretic
boolean
C1579268 (UMLS CUI [1])
C1960108 (UMLS CUI [2])
C0304490 (UMLS CUI [3])