Chronic congestive heart failure
Item
have a diagnosis of chronic congestive heart failure of any etiology
boolean
C0264722 (UMLS CUI [1])
Age
Item
be between 18-80 years of age
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
able to provide consent
boolean
C0021430 (UMLS CUI [1])
Left ventricular ejection fraction
Item
have a documented left ventricular ejection fraction within the last year of < 40%
boolean
C0428772 (UMLS CUI [1])
Furosemide Dose Stable U/day | Equivalent Dose Stable U/day
Item
on a stable dose (no changes within 2 weeks) of 40 mg or greater daily dose of furosemide or its equivalent
boolean
C0016860 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0456683 (UMLS CUI [1,4])
C0205163 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0456683 (UMLS CUI [2,4])
Standard of Care Pharmaceutical Preparations Heart failure | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-Antagonists | Exception Medical contraindication
Item
on standard hf therapy medications (acei or arb and beta-blocker unless contraindicated)
boolean
C2936643 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
C0003015 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0001645 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C1301624 (UMLS CUI [5,2])
Estimated Glomerular Filtration Rate Cockcroft-Gault formula
Item
have an estimated glomerular filtration rate (gfr) of 30 ml/minute or greater (based on the cockcroft gault calculation)
boolean
C3811844 (UMLS CUI [1,1])
C2924627 (UMLS CUI [1,2])
Hemoglobin measurement
Item
have a hemoglobin of > 10 grams/dl
boolean
C0518015 (UMLS CUI [1])
Childbearing Potential Urine pregnancy test negative
Item
have a negative urine pregnancy for women of childbearing years only
boolean
C3831118 (UMLS CUI [1,1])
C0430057 (UMLS CUI [1,2])
Acute Coronary Syndrome
Item
acute coronary syndrome within 1 month
boolean
C0948089 (UMLS CUI [1])
Systolic Pressure
Item
systolic blood pressure less than or equal to 90 mmhg at time of enrollment
boolean
C0871470 (UMLS CUI [1])
Peripheral venous access Poor
Item
poor peripheral venous access
boolean
C4489703 (UMLS CUI [1,1])
C0542537 (UMLS CUI [1,2])
Comorbidity Severe | Study Subject Participation Status Inappropriate
Item
severe concomitant disease which deemed by the investigator would render them unsuitable for this trial
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
Hypersensitivity Iothalamate | Medical contraindication Iothalamate | Hypersensitivity p-Aminohippuric Acid | Medical contraindication p-Aminohippuric Acid | Iodine allergy | Hypersensitivity Preparations Containing Iodine | Asthma | Hay fever | Study Subject Participation Status Inappropriate
Item
allergy or contraindication to the use of iothalamate, pah - specifically any allergies to iodine or iodine containing products, history of asthma and hay fever which deemed by the investigator would render them unsuitable for this trial
boolean
C0020517 (UMLS CUI [1,1])
C0022032 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0022032 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0030123 (UMLS CUI [3,2])
C1301624 (UMLS CUI [4,1])
C0030123 (UMLS CUI [4,2])
C0571818 (UMLS CUI [5])
C0020517 (UMLS CUI [6,1])
C0013227 (UMLS CUI [6,2])
C0332256 (UMLS CUI [6,3])
C0021968 (UMLS CUI [6,4])
C0004096 (UMLS CUI [7])
C0018621 (UMLS CUI [8])
C2348568 (UMLS CUI [9,1])
C1548788 (UMLS CUI [9,2])