Age
Item
1. age>18
boolean
C0001779 (UMLS CUI [1])
Congestive heart failure Duration
Item
2. congestive heart failure (chf) (>6 months duration)
boolean
C0018802 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Left ventricular ejection fraction
Item
3. left ventricular ejection fraction (lvef) <40%
boolean
C0428772 (UMLS CUI [1])
New York Heart Association Classification
Item
4. functional class ii-iii
boolean
C1275491 (UMLS CUI [1])
Therapy Oral medication Stable
Item
5. stable oral treatment (>1 month),
boolean
C0087111 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Artificial cardiac pacemaker | Implantable defibrillator | Other Coding
Item
6. implanted medtronic pacemaker/defibrillator with a) an atrial pacing lead and biventricular leads, or b) an atrial pacing lead and a single ventricular lead in patients with a narrow (normal) qrs complex (<120 msec) thus with no clinical indication for biventricular pacing.
boolean
C0030163 (UMLS CUI [1])
C0162589 (UMLS CUI [2])
C3846158 (UMLS CUI [3])
Bradycardia | Sinus rhythm | Atrial pacing pattern BPM
Item
7. low heart rate (hr) (sinus rhythm (sr) or atrial pacing <70 bpm)
boolean
C0428977 (UMLS CUI [1])
C0232201 (UMLS CUI [2])
C0429117 (UMLS CUI [3,1])
C0439385 (UMLS CUI [3,2])
Symptoms Stable | Requirement Absent Diuretics
Item
8. symptomatically stable (with no clinical requirement for adjustments in medical therapy, i.e. diuretics)
boolean
C1457887 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
C1514873 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0012798 (UMLS CUI [2,3])
Thoracic Fluid Increased | Brain natriuretic peptide measurement
Item
9. increase in intrathoracic fluid as evidenced by rain natriuretic peptide (bnp) >200.
boolean
C4288132 (UMLS CUI [1,1])
C0205217 (UMLS CUI [1,2])
C1095989 (UMLS CUI [2])
Atrial Fibrillation
Item
1. atrial fibrillation
boolean
C0004238 (UMLS CUI [1])
Stable angina | Angina, Unstable
Item
2. stable or unstable angina
boolean
C0340288 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
Recent myocardial infarction
Item
3. myocardial infarction within 6 months before the study
boolean
C1998297 (UMLS CUI [1])
Inotropic agent Intravenous
Item
4. intravenous inotropic support
boolean
C0304509 (UMLS CUI [1,1])
C1522726 (UMLS CUI [1,2])
Pregnancy | Breast Feeding | Childbearing Potential Serum pregnancy test negative
Item
5. pregnant or breast feeding women. women of child bearing potential must have a negative serum pregnancy test prior to enrollment.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0430061 (UMLS CUI [3,2])
Kidney Failure Severe | Creatinine measurement, serum | Hemodialysis | Peritoneal Dialysis
Item
6. severe renal failure (creatinine> 2.5 mg/dl, hemodyalisis or peritoneal dialysis)
boolean
C0035078 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0201976 (UMLS CUI [2])
C0019004 (UMLS CUI [3])
C0031139 (UMLS CUI [4])
Hepatic impairment | Serum total bilirubin measurement | Albumin measurement | Increased serum ammonia
Item
7. known hepatic impairment (total bilirubin >3 mg/dl, albumin <2.8 mg/dl, or increased ammonia levels if performed)
boolean
C0948807 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0201838 (UMLS CUI [3])
C0740942 (UMLS CUI [4])
Hemoglobin measurement | Hemorrhage Requirement Transfusion
Item
8. hemoglobin (hgb) <8 mg %, or active bleeding requiring transfusion
boolean
C0518015 (UMLS CUI [1])
C0019080 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C1879316 (UMLS CUI [2,3])