Diffuse Large B-Cell Lymphoma de novo | Follicular Lymphoma Ann Arbor lymphoma staging system
Item
1. histologically confirmed de novo diffuse large b-cell lymphoma or follicular lymphoma grade 3b
boolean
C0079744 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C0024301 (UMLS CUI [2,1])
C0432516 (UMLS CUI [2,2])
Age
Item
2. age>=16 y.o.,<=80 y.o.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
3. ecog < 3
boolean
C1520224 (UMLS CUI [1])
Malignant Neoplasm Absent
Item
4. no past history of malignancy
boolean
C0006826 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Measurable Disease | Lesion Quantity CT | Lesion Longest Diameter
Item
5. radiologically measurable disease, ct imaging in screening showing 2 or more clearly demarcated lesions with a largest diameter > 1.5 cm, or 1 clearly demarcated lesion with a largest diameter > 2.0 cm.
boolean
C1513041 (UMLS CUI [1])
C0221198 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0040405 (UMLS CUI [2,3])
C0221198 (UMLS CUI [3,1])
C0552406 (UMLS CUI [3,2])
Life Expectancy
Item
6. life expectancy>6 months
boolean
C0023671 (UMLS CUI [1])
Informed Consent
Item
7. informed consented
boolean
C0021430 (UMLS CUI [1])
Chemotherapy
Item
1. chemotherapy before
boolean
C0392920 (UMLS CUI [1])
Bone Marrow Transplantation
Item
2. bone marrow transplantation before
boolean
C0005961 (UMLS CUI [1])
Malignant Neoplasms
Item
3. history of malignancy
boolean
C0006826 (UMLS CUI [1])
Communicable Disease Requirement Antibiotics General | Communicable Disease Requirement Antifungal therapy | Communicable Disease Requirement Antiviral Therapy
Item
4. active infectious disease requiring general antibiotics, anti-fungal or anti-virus therapy
boolean
C0009450 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0003232 (UMLS CUI [1,3])
C0205246 (UMLS CUI [1,4])
C0009450 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0678026 (UMLS CUI [2,3])
C0009450 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
C0280274 (UMLS CUI [3,3])
Cardiovascular Disease Uncontrolled | Cerebrovascular Disorder Uncontrolled | Blood Coagulation Disorder Uncontrolled | Autoimmune Disease Uncontrolled | Communicable Disease Serious Uncontrolled
Item
5. uncontrollable cardio-cerebral vascular, coagulative, autoimmune, serious infectious disease
boolean
C0007222 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0007820 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0005779 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
C0004364 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
C0009450 (UMLS CUI [5,1])
C0205404 (UMLS CUI [5,2])
C0205318 (UMLS CUI [5,3])
Primary cutaneous diffuse large cell B-cell lymphoma | Diffuse large B-cell lymphoma of central nervous system | Mediastinal (Thymic) Large B-Cell Lymphoma
Item
6. primary cutaneous, cns, mediastinal dlbcl
boolean
C1275325 (UMLS CUI [1])
C2026186 (UMLS CUI [2])
C1292754 (UMLS CUI [3])
Left ventricular ejection fraction
Item
7. lvef≤50%
boolean
C0428772 (UMLS CUI [1])
Other medical condition Uncontrolled Interferes with Study Subject Participation Status
Item
8. other uncontrollable medical condition that may that may interfere the participation of the study
boolean
C3843040 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C2348568 (UMLS CUI [1,4])
Laboratory test finding | Exception Caused by Lymphoma
Item
9. lab at enrollment(unless caused by lymphoma)
boolean
C0587081 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0015127 (UMLS CUI [2,2])
C0024299 (UMLS CUI [2,3])
Neutrophil count
Item
neutrophile<1.5*10^9/l
boolean
C0200633 (UMLS CUI [1])
Platelet Count measurement
Item
platelet<80*10^9/l
boolean
C0032181 (UMLS CUI [1])
Hemoglobin measurement
Item
hemoglobulin<100g/l
boolean
C0518015 (UMLS CUI [1])
Alanine aminotransferase increased | Aspartate aminotransferase increased | Alkaline phosphatase raised | Serum bilirubin increased
Item
alt or ast >2*uln,akp or bilirubin >1.5*uln
boolean
C0151905 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
C0151849 (UMLS CUI [3])
C0859062 (UMLS CUI [4])
Creatinine increased
Item
creatinine>1.5*uln
boolean
C0151578 (UMLS CUI [1])
Protocol Compliance Unable | Etiology Mental condition | Reason unknown
Item
10. not able to comply to the protocol for mental or other unknown reasons
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0015127 (UMLS CUI [2,1])
C3840291 (UMLS CUI [2,2])
C3840856 (UMLS CUI [3])
Pregnancy | Breast Feeding
Item
11. pregnant or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Liver disease | Biliary Tract Disease
Item
12. active liver or biliary disease
boolean
C0023895 (UMLS CUI [1])
C0005424 (UMLS CUI [2])
HbsAg positive Hbv DNA Test | Hepatitis B DNA assay positive
Item
13. if hbsag positive, should check hbv dna, dna positive patients cannot be enrolled. if hbsag negative but hbcab positive (whatever hbsab status), should check hbv dna,dna positive patients cannot be enrolled.
boolean
C0149709 (UMLS CUI [1,1])
C1256114 (UMLS CUI [1,2])
C1168040 (UMLS CUI [2])
HIV Infection
Item
14. hiv infection
boolean
C0019693 (UMLS CUI [1])