Body mass index
Item
1. bmi (k/m2) >= 95th percentile;
boolean
C1305855 (UMLS CUI [1])
Body Weight
Item
2. weight 150 - 400 pounds;
boolean
C0005910 (UMLS CUI [1])
Language ability English Language | Language ability Spanish Language
Item
3. language: english or spanish (the pi speaks both english and spanish fluently).
boolean
C1145677 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C1145677 (UMLS CUI [2,1])
C0037750 (UMLS CUI [2,2])
Diabetes Mellitus, Non-Insulin-Dependent
Item
1. history of t2dm;
boolean
C0011860 (UMLS CUI [1])
Pharmacotherapy Effect Diabetes risk
Item
2. prior or current drug treatmeant that would effect diabetes risk
boolean
C0013216 (UMLS CUI [1,1])
C1280500 (UMLS CUI [1,2])
C1171304 (UMLS CUI [1,3])
Glucocorticoids Prescription
Item
3. use of prescription strength glucocorticoids within three months before screening,
boolean
C0017710 (UMLS CUI [1,1])
C0033080 (UMLS CUI [1,2])
Syndrome Associated with Obesity | Disease Associated with Obesity
Item
4. history of syndrome or medical disorder associated with significant obesity;
boolean
C0039082 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C0028754 (UMLS CUI [1,3])
C0012634 (UMLS CUI [2,1])
C0332281 (UMLS CUI [2,2])
C0028754 (UMLS CUI [2,3])
Creatinine measurement, serum
Item
5. serum creatinine >1.2 mg/dl;
boolean
C0201976 (UMLS CUI [1])
Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
6. alanine transaminase (alt) or aspartate aminotransferase (ast) >90 international units (iu)/l (= 3 x normal limits);
boolean
C0151905 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
Elevated total bilirubin
Item
7. total bilirubin >2.5 time the upper limit of normal;
boolean
C0741494 (UMLS CUI [1])
Moderate physical activity | Physical activity Extreme | Pregnancy
Item
8. history of moderate to extreme physical activity, past or current pregnancy;
boolean
C4482418 (UMLS CUI [1])
C0026606 (UMLS CUI [2,1])
C0205403 (UMLS CUI [2,2])
C0032961 (UMLS CUI [3])
Illicit medication use
Item
9 .use of illegal/illicit drugs;
boolean
C0281875 (UMLS CUI [1])
Protocol Compliance Unable
Item
10. unable to comply with the protocol;
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Disease Serious Study Subject Participation Status At risk
Item
11. any other serious disease determined by the clinician as potential study risk for the patient.
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C1444641 (UMLS CUI [1,4])
Kidney Diseases | Liver diseases | Condition Resulting in Ammonia Accumulation
Item
12. have kidney or liver disorders, or conditions resulting in ammonia accumulation
boolean
C0022658 (UMLS CUI [1])
C0023895 (UMLS CUI [2])
C0348080 (UMLS CUI [3,1])
C0332294 (UMLS CUI [3,2])
C0002607 (UMLS CUI [3,3])
C4055506 (UMLS CUI [3,4])
Lactulose
Item
13. take lactulose
boolean
C0022957 (UMLS CUI [1])
Hypersensitivity Sodium Glutamate | Hypersensitivity Glutamine | Other Coding
Item
14. are allergic to monosodium glutamate (msg), glutamine, or crystal light
boolean
C0020517 (UMLS CUI [1,1])
C0037511 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0017797 (UMLS CUI [2,2])
C3846158 (UMLS CUI [3])
Manic episodes
Item
15. have manic episodes (mental illness)
boolean
C0349208 (UMLS CUI [1])
Anticonvulsant therapy
Item
16. take medications to prevent seizures
boolean
C0521306 (UMLS CUI [1])
Glutamine | Glutamine Supplements | Hypoglycemic Agents | Anticonvulsants | Pharmaceutical Preparations Attention deficit hyperactivity disorder | Antilipidemic Agent | Thyroid Hormones
Item
17. take any glutamine, supplement with glutamine, hypoglycemiants, anticonvulsivant, adhd medications, antilipidemiants, or thyroid hormone
boolean
C0017797 (UMLS CUI [1])
C0017797 (UMLS CUI [2,1])
C0242295 (UMLS CUI [2,2])
C0020616 (UMLS CUI [3])
C0003286 (UMLS CUI [4])
C0013227 (UMLS CUI [5,1])
C1263846 (UMLS CUI [5,2])
C1516000 (UMLS CUI [6])
C0040135 (UMLS CUI [7])
Participation Weight Reduction Programs | Weight-Loss Agents | Weight loss Percentage Timespan
Item
18. participation in a weight loss program or use of weight loss medications within six months of screening that has resulted in 5% or more weight loss
boolean
C0679823 (UMLS CUI [1,1])
C3179079 (UMLS CUI [1,2])
C0376606 (UMLS CUI [2])
C1262477 (UMLS CUI [3,1])
C0439165 (UMLS CUI [3,2])
C0872291 (UMLS CUI [3,3])