Diabetes Mellitus, Non-Insulin-Dependent
Item
diagnosed with type 2 diabetes
boolean
C0011860 (UMLS CUI [1])
Antidiabetics Oral Absent
Item
never taken oral antidiabetic drugs before
boolean
C0935929 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Hemoglobin A1c measurement
Item
hba1c greater than 8.5 %
boolean
C0474680 (UMLS CUI [1])
Body mass index
Item
bmi (body mass index) less than or equal to 35 kg/m^2
boolean
C1305855 (UMLS CUI [1])
Hypersensitivity Repaglinide | Hypersensitivity Suspected Repaglinide | Metformin allergy | Metformin allergy Suspected | Hypersensitivity Repaglinide Excipient | Hypersensitivity Suspected Repaglinide Excipient | Hypersensitivity Metformin Excipient | Hypersensitivity Suspected Metformin Excipient
Item
known or suspected allergy to repaglinide, metformin, or any of the excipients in the medications
boolean
C0020517 (UMLS CUI [1,1])
C0246689 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
C0246689 (UMLS CUI [2,3])
C0571648 (UMLS CUI [3])
C0571648 (UMLS CUI [4,1])
C0750491 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0246689 (UMLS CUI [5,2])
C0015237 (UMLS CUI [5,3])
C0020517 (UMLS CUI [6,1])
C0750491 (UMLS CUI [6,2])
C0246689 (UMLS CUI [6,3])
C0015237 (UMLS CUI [6,4])
C0020517 (UMLS CUI [7,1])
C0025598 (UMLS CUI [7,2])
C0015237 (UMLS CUI [7,3])
C0020517 (UMLS CUI [8,1])
C0750491 (UMLS CUI [8,2])
C0025598 (UMLS CUI [8,3])
C0015237 (UMLS CUI [8,4])
Study Subject Participation Status | Investigational New Drugs
Item
taken an investigational drug in another clinical trial within 4 weeks prior to this trial
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Liver Dysfunction | Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
impaired liver function, defined as asat (aspartate aminotransferase) or alat (alanine aminotransferase) equal to or greater than 2 times upper normal limit
boolean
C0086565 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
C0151905 (UMLS CUI [3])
Gastrointestinal Disease | Lung disease | Nervous system disorder | Kidney Disease | Disorder of the genitourinary system | Hematological Disease
Item
have a clinically significant, active disease of the gastrointestinal, pulmonary, neurological, renal, genitourinary, and haematological systems
boolean
C0017178 (UMLS CUI [1])
C0024115 (UMLS CUI [2])
C0027765 (UMLS CUI [3])
C0022658 (UMLS CUI [4])
C0080276 (UMLS CUI [5])
C0018939 (UMLS CUI [6])
Uncontrolled hypertension Severe | Severe hypertension untreated | Sitting diastolic blood pressure | Sitting systolic blood pressure
Item
severe uncontrolled or untreated hypertension (sitting diastolic blood pressure (bp) equal to or greater than 100 mmhg or systolic bp equal to or greater than 180 mmhg)
boolean
C1868885 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C4013784 (UMLS CUI [2,1])
C0332155 (UMLS CUI [2,2])
C1319894 (UMLS CUI [3])
C1319893 (UMLS CUI [4])
Renal Insufficiency
Item
impaired renal function
boolean
C1565489 (UMLS CUI [1])
Acidosis | Chronic acidosis | Radiographic contrast material Containing Iodine
Item
acute or chronic acidosis or if there are plans to have a radiographic material containing iodine
boolean
C0001122 (UMLS CUI [1])
C1735903 (UMLS CUI [2])
C0009924 (UMLS CUI [3,1])
C0332256 (UMLS CUI [3,2])
C0021968 (UMLS CUI [3,3])
Cardiovascular Disease | Decompensated cardiac failure
Item
have a clinically significant, active cardiovascular disease, or decompensated heart failure
boolean
C0007222 (UMLS CUI [1])
C0581377 (UMLS CUI [2])
CORTICOSTEROIDS FOR SYSTEMIC USE
Item
treatment with systemic corticosteroids within the past two months prior to screening
boolean
C3653708 (UMLS CUI [1])