Age | Skin Neoplasms | Secondary malignant neoplasm of skin | Prior radiation therapy | Prior radiation therapy Absent
Item
patients > 18 years of age, with primary or metastatic cutaneous tumors that may or may not have been previously irradiated.
boolean
C0001779 (UMLS CUI [1])
C0037286 (UMLS CUI [2])
C0153687 (UMLS CUI [3])
C0279134 (UMLS CUI [4])
C0279134 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
ECOG performance status
Item
ecog performance status < 3.
boolean
C1520224 (UMLS CUI [1])
Absence Cancer treatment Systemic
Item
patients must not have received any systemic anti-cancer therapy within 30 days prior to enrolling in this study.
boolean
C0332197 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
C0205373 (UMLS CUI [1,3])
Absence Therapeutic radiology procedure Target Site
Item
patients must not have received radiation therapy to the target site within 60 days of enrolling on this study.
boolean
C0332197 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
C2348654 (UMLS CUI [1,3])
Skin Target Site Grade | Skin Control Site Grade
Item
skin of target site and control site must be grade 0 or 1 by common terminology
boolean
C1123023 (UMLS CUI [1,1])
C2348654 (UMLS CUI [1,2])
C0441800 (UMLS CUI [1,3])
C1123023 (UMLS CUI [2,1])
C0243148 (UMLS CUI [2,2])
C1515974 (UMLS CUI [2,3])
C0441800 (UMLS CUI [2,4])
Target Lesion Identification | Skin of periumbilical region Normal
Item
patients must have a target lesion and normal peri-umbilical skin that can be covered by the fiber-optic mesh used to deliver clipt (10 x 10 cm, or 3 x 3).
boolean
C2986546 (UMLS CUI [1])
C0448830 (UMLS CUI [2,1])
C0205307 (UMLS CUI [2,2])
Target Lesion Location Extremity | Target Lesion Percentage Diameter Extremity
Item
if located on an extremity, the target lesion must not cover more than 50% of the diameter of the extremity at the level at which it is located.
boolean
C2986546 (UMLS CUI [1,1])
C1515974 (UMLS CUI [1,2])
C0015385 (UMLS CUI [1,3])
C2986546 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C1301886 (UMLS CUI [2,3])
C0015385 (UMLS CUI [2,4])
Absolute neutrophil count
Item
absolute neutrophil count > 1000.
boolean
C0948762 (UMLS CUI [1])
Blood coagulation status | Platelet Count measurement | Prothrombin time assay | Activated Partial Thromboplastin Time measurement
Item
adequate coagulation status as indicated by platelet count > 50,000, pt and ptt < 1.5 time the upper limit of normal.
boolean
C1321069 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0033707 (UMLS CUI [3])
C0030605 (UMLS CUI [4])
Informed Consent
Item
patients must sign informed consent.
boolean
C0021430 (UMLS CUI [1])
Gender
Item
male patients not considered for this study.
boolean
C0079399 (UMLS CUI [1])
Target Lesion Location Hands | Target Lesion Location Feet | Target Lesion Location Genitals | Target Lesion Location Face
Item
patients must have a target lesion in a location other than the hands, feet, genitals, or face. lesions in those locations will be excluded.
boolean
C2986546 (UMLS CUI [1,1])
C1515974 (UMLS CUI [1,2])
C0018563 (UMLS CUI [1,3])
C2986546 (UMLS CUI [2,1])
C1515974 (UMLS CUI [2,2])
C0016504 (UMLS CUI [2,3])
C2986546 (UMLS CUI [3,1])
C1515974 (UMLS CUI [3,2])
C0017420 (UMLS CUI [3,3])
C2986546 (UMLS CUI [4,1])
C1515974 (UMLS CUI [4,2])
C0015450 (UMLS CUI [4,3])
Medical condition Associated with Photosensitivity | Porphyria variegata, cutaneous | Collagen-vascular disease | Hypersensitivity Porphyrins
Item
patients with medical conditions associated with photosensitivity, such as cutaneous porphyria or a collagen vascular disease, or with known allergies to porphyrins will be excluded.
boolean
C3843040 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C0349506 (UMLS CUI [1,3])
C0543653 (UMLS CUI [2])
C0262428 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0032712 (UMLS CUI [4,2])
Pregnancy | Breast Feeding | Childbearing Potential Serum pregnancy test negative | Childbearing Potential Urine pregnancy test negative
Item
pregnant and nursing patients will be excluded. women of child-bearing potential must have a negative serum or urine pregnancy test prior to enrollment.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0430061 (UMLS CUI [3,2])
C3831118 (UMLS CUI [4,1])
C0430057 (UMLS CUI [4,2])
Pharmaceutical Preparations Causing Photosensitivity | Tetracycline | Sulfonamides | phenothiazine | Sulfonylurea Compounds | Hypoglycemic Agents | Thiazide Diuretics | Griseofulvin | Fluoroquinolones | ST. JOHN'S WORT EXTRACT | Amiodarone
Item
patients taking medications known to cause photosensitivity (tetracyclines, sulfonamides, phenothiazines, sulfonylurea hypoglycemic agents, thiazide diuretics, griseofulvin, and fluoroquinolones, st. john's wort and amiodarone) will be excluded.
boolean
C0013227 (UMLS CUI [1,1])
C0678227 (UMLS CUI [1,2])
C0349506 (UMLS CUI [1,3])
C0039644 (UMLS CUI [2])
C0038760 (UMLS CUI [3])
C0031434 (UMLS CUI [4])
C0038766 (UMLS CUI [5])
C0020616 (UMLS CUI [6])
C0012802 (UMLS CUI [7])
C0018242 (UMLS CUI [8])
C0949665 (UMLS CUI [9])
C0813171 (UMLS CUI [10])
C0002598 (UMLS CUI [11])
Liver Dysfunction Severe | Elevated total bilirubin | Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
patients with severe hepatic dysfunction (total bilirubin, ast, or alt > five times upper limit of normal) will be excluded.
boolean
C0086565 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0741494 (UMLS CUI [2])
C0151904 (UMLS CUI [3])
C0151905 (UMLS CUI [4])