Adult | Cardiac Surgery elective Expected | Informed Consent | Sinus rhythm | Anti-Arrhythmia Agents Absent | Exception Adrenergic beta-Antagonists
Item
adult patients awaiting elective cardiac surgery who are willing and able to give informed consent for participation in the study and who are in sinus rhythm and not taking any antiarrhythmic medication, other than beta-adrenergic blocking agents, at the time of surgery.
boolean
C0001675 (UMLS CUI [1])
C0018821 (UMLS CUI [2,1])
C0439608 (UMLS CUI [2,2])
C1517001 (UMLS CUI [2,3])
C0021430 (UMLS CUI [3])
C0232201 (UMLS CUI [4])
C0003195 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C0001645 (UMLS CUI [6,2])
Hepatobiliary disease Obstructive | Liver disease Serious
Item
history of obstructive hepato-biliary disease or other serious hepatic disease
boolean
C0267792 (UMLS CUI [1,1])
C0549186 (UMLS CUI [1,2])
C0023895 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
Hypothyroidism Untreated
Item
untreated hypothyroidism
boolean
C0020676 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Creatinine measurement, serum
Item
creatinine > 200 umol/l
boolean
C0201976 (UMLS CUI [1])
Hereditary muscle disorders | Family history Hereditary muscle disorders
Item
personal and family history of hereditary muscle disorders
boolean
C0852407 (UMLS CUI [1])
C0241889 (UMLS CUI [2,1])
C0852407 (UMLS CUI [2,2])
Intolerance to Statins | Muscle Toxicity Fibrates | Muscle Toxicity Statins
Item
known intolerance to statins or history of muscle toxicity with fibrates or statins.
boolean
C1744706 (UMLS CUI [1,1])
C0360714 (UMLS CUI [1,2])
C0026845 (UMLS CUI [2,1])
C0600688 (UMLS CUI [2,2])
C1449704 (UMLS CUI [2,3])
C0026845 (UMLS CUI [3,1])
C0600688 (UMLS CUI [3,2])
C0360714 (UMLS CUI [3,3])
Fibrates | Niacin | Cytochrome P450 Inhibitors Strong | P-Glycoprotein Inhibitors Strong | Cyclosporine | Azole antifungal Oral | Macrolide Antibiotics | Protease Inhibitors | nefazodone | Amiodarone | GRAPEFRUIT JUICE L/day
Item
on-going use of fibrates, niacin or of agents that are strong inhibitors of cytochrome p-450 or the p-glycoprotein within a month preceding randomization (cyclosporine, oral azole antifungals,macrolide antibiotics, protease inhibitors, nefazodone, amiodarone or ≥ 1l/day of grapefruit juice)
boolean
C1449704 (UMLS CUI [1])
C0027996 (UMLS CUI [2])
C2962191 (UMLS CUI [3,1])
C0442821 (UMLS CUI [3,2])
C3500483 (UMLS CUI [4,1])
C0442821 (UMLS CUI [4,2])
C0010592 (UMLS CUI [5])
C0360363 (UMLS CUI [6,1])
C1527415 (UMLS CUI [6,2])
C0003240 (UMLS CUI [7])
C0033607 (UMLS CUI [8])
C0068485 (UMLS CUI [9])
C0002598 (UMLS CUI [10])
C0452456 (UMLS CUI [11,1])
C0475219 (UMLS CUI [11,2])
Diseases of mitral valve | Mitral Valve Insufficiency Moderate Grade | Mitral Valve Insufficiency Severe Grade | Mitral Valve Stenosis | Mitral valve annular calcification
Item
significant mitral valve disease (moderate or severe mitral regurgitation-eg. > grade ii and/or mitral stenosis & mitral annular calcification).
boolean
C0026265 (UMLS CUI [1])
C0026266 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0441800 (UMLS CUI [2,3])
C0026266 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0441800 (UMLS CUI [3,3])
C0026269 (UMLS CUI [4])
C0428811 (UMLS CUI [5])
Anti-Arrhythmia Agents | Exception Adrenergic beta-Antagonists
Item
patients treated with any anti-arrhythmic agent (other than beta-adrenergic receptor blockers).
boolean
C0003195 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0001645 (UMLS CUI [2,2])