Age
Item
patients age 18 or older.
boolean
C0001779 (UMLS CUI [1])
Paroxysmal atrial fibrillation Symptomatic | Unresponsive to Anti-Arrhythmia Agents Quantity
Item
patients with paroxysmal af symptomatic and refractory to at least one antiarrhythmic medication.
boolean
C0235480 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0205269 (UMLS CUI [2,1])
C0003195 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
Paroxysmal atrial fibrillation | Episode of Atrial Fibrillation Quantity ECG | Episode of Atrial Fibrillation Quantity Holter Electrocardiography
Item
in patients with paroxysmal af, at least one episode of af must have been documented by ecg or holter within 12 months of randomization in the trial.
boolean
C0235480 (UMLS CUI [1])
C0332189 (UMLS CUI [2,1])
C0004238 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0013798 (UMLS CUI [2,4])
C0332189 (UMLS CUI [3,1])
C0004238 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
C0013801 (UMLS CUI [3,4])
Persistent atrial fibrillation | Episode of Atrial Fibrillation Duration | Episode of Sinus rhythm Absent | Recurrent episode Post Cardioversion
Item
patients with persistent af defined as a sustained episode that had been present for more than seven days without intervening spontaneous episodes of sinus rhythm and that recurred within seven days after cardioversion.
boolean
C2585653 (UMLS CUI [1])
C0332189 (UMLS CUI [2,1])
C0004238 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
C0332189 (UMLS CUI [3,1])
C0232201 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
C0443287 (UMLS CUI [4,1])
C0687676 (UMLS CUI [4,2])
C0013778 (UMLS CUI [4,3])
Persistent atrial fibrillation | Anticoagulation Therapy | Warfarin | INR | Status pre- Ablation | Paroxysmal atrial fibrillation | Echocardiography, Transesophageal | Thrombi Excluded | Abnormality Excluded
Item
patients with persistent af must be on continuous anticoagulation with warfarin (inr 2-3) for> 4 weeks prior to ablation. in patients with paroxysmal af no continuous anticoagulation therapy with warfarin for > 4 weeks prior to ablation will be needed provided a transesophageal echocardiogram performed prior to ablation exclude the presence of thrombi or other abnormalities that discourage performing the procedure.
boolean
C2585653 (UMLS CUI [1])
C0003281 (UMLS CUI [2])
C0043031 (UMLS CUI [3])
C0525032 (UMLS CUI [4])
C0332152 (UMLS CUI [5,1])
C0547070 (UMLS CUI [5,2])
C0235480 (UMLS CUI [6])
C0206054 (UMLS CUI [7])
C0087086 (UMLS CUI [8,1])
C0332196 (UMLS CUI [8,2])
C1704258 (UMLS CUI [9,1])
C0332196 (UMLS CUI [9,2])
Informed Consent
Item
patients must be able and willing to provide written informed consent to participate in the clinical trial.
boolean
C0021430 (UMLS CUI [1])
Atrial Fibrillation Secondary to Cause Reversible
Item
patients with af secondary to reversible causes.
boolean
C0004238 (UMLS CUI [1,1])
C0175668 (UMLS CUI [1,2])
C0015127 (UMLS CUI [1,3])
C0205343 (UMLS CUI [1,4])
Anticoagulation drug level Inadequate
Item
patients with inadequate anticoagulation levels as defined in the inclusion criteria.
boolean
C1168142 (UMLS CUI [1,1])
C0205412 (UMLS CUI [1,2])
Thrombus of left atrium | Neoplasm | Abnormality Excludes Catheterization Transesophageal Echocardiography
Item
patients with left atrial thrombus, tumor, or another abnormality which precludes catheter introduction on tee prior to the procedure.
boolean
C3532827 (UMLS CUI [1])
C0027651 (UMLS CUI [2])
C1704258 (UMLS CUI [3,1])
C0332196 (UMLS CUI [3,2])
C0007430 (UMLS CUI [3,3])
C0206054 (UMLS CUI [3,4])
Medical contraindication Anticoagulation Therapy Systemic | Medical contraindication Heparin | Medical contraindication Coumadin
Item
patients with contraindications to systemic anticoagulation with heparin or coumadin.
boolean
C1301624 (UMLS CUI [1,1])
C0003281 (UMLS CUI [1,2])
C0205373 (UMLS CUI [1,3])
C1301624 (UMLS CUI [2,1])
C0019134 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C0699129 (UMLS CUI [3,2])
Atrial Fibrillation Ablation | Operative Surgical Procedures | Catheter Ablation, Percutaneous
Item
patients who have previously undergone atrial fibrillation ablation, either by surgery or by percutaneous catheter.
boolean
C0004238 (UMLS CUI [1,1])
C0547070 (UMLS CUI [1,2])
C0543467 (UMLS CUI [2])
C0162560 (UMLS CUI [3])
Left atrium Size
Item
patients with left atrial size > 55 mm.
boolean
C0225860 (UMLS CUI [1,1])
C0456389 (UMLS CUI [1,2])
Pregnancy | Possible pregnancy
Item
patients who are or may potentially be pregnant.
boolean
C0032961 (UMLS CUI [1])
C0425965 (UMLS CUI [2])
Hyperthyroidism | Hypothyroidism
Item
patients with hyperthyroidism or hypothyroidism.
boolean
C0020550 (UMLS CUI [1])
C0020676 (UMLS CUI [2])
Study Subject Participation Status | Investigational New Drugs | Investigational Medical Device
Item
current enrollment in another investigational drug or device study.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
C2346570 (UMLS CUI [3])
Artificial cardiac pacemaker | Implantable defibrillator
Item
pacemaker or implantable cardioverter defibrillator.
boolean
C0030163 (UMLS CUI [1])
C0162589 (UMLS CUI [2])