Able to communicate Research Personnel | Legal competency Informed Consent
Item
able to communicate meaningfully with the investigator and legally competent to provide informed written consent
boolean
C2364293 (UMLS CUI [1,1])
C0035173 (UMLS CUI [1,2])
C0680554 (UMLS CUI [2,1])
C0021430 (UMLS CUI [2,2])
Age
Item
18-65 years of age
boolean
C0001779 (UMLS CUI [1])
Body mass index | Study Subject Lean | Study Subject Obese
Item
bmi of 20-25 kg/m2 (lean subjects); 30-35 kg/m2 (obese subjects)
boolean
C1305855 (UMLS CUI [1])
C0681850 (UMLS CUI [2,1])
C0424678 (UMLS CUI [2,2])
C0681850 (UMLS CUI [3,1])
C0028754 (UMLS CUI [3,2])
Stable body weight
Item
stable body weight (< 3 kg change in the last 8 weeks)
boolean
C0517386 (UMLS CUI [1])
Homeostasis model assessment Insulin Resistance Measurement | Study Subject Lean | Study Subject Obese
Item
homeostatic model assessment (homa)-insulin resistance <2.7 if lean; homeostatic model assessment (homa)-insulin resistance ≥2.7 if obese
boolean
C1829779 (UMLS CUI [1,1])
C4049994 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0424678 (UMLS CUI [2,2])
C0681850 (UMLS CUI [3,1])
C0028754 (UMLS CUI [3,2])
Breast Feeding | Pregnancy
Item
lactation or pregnancy, current and/or within last 6 months, per participant's report
boolean
C0006147 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
Postmenopausal state
Item
female subjects postmenopausal
boolean
C0232970 (UMLS CUI [1])
Cardiovascular Disease | Angina, Unstable | Myocardial Infarction | Coronary revascularisation
Item
cardiovascular disease (unstable angina, myocardial infarction or coronary revascularization within 6 months)
boolean
C0007222 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0027051 (UMLS CUI [3])
C0877341 (UMLS CUI [4])
Liver disease | Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
liver disease (ast or alt(alanine aminotransferase)>2.5 times the upper limit of normal)
boolean
C0023895 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
C0151905 (UMLS CUI [3])
Kidney Disease | Creatinine measurement, serum
Item
kidney disease (creatinine >1.6 mg/dl)
boolean
C0022658 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Anemia | Hemoglobin measurement | Gender
Item
anemia (hemoglobin <12 g/dl in men, <11 g/dl in women)
boolean
C0002871 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0079399 (UMLS CUI [3])
Thyroid dysfunction | Serum TSH level abnormal
Item
thyroid dysfunction (abnormal tsh)
boolean
C0348024 (UMLS CUI [1])
C0580434 (UMLS CUI [2])
Hemoglobin A1c measurement
Item
hba1c ≥6.5%
boolean
C0474680 (UMLS CUI [1])
Uncontrolled hypertension | Systolic Pressure | Diastolic blood pressure
Item
uncontrolled hypertension (systolic bp>160 mmhg, diastolic bp>100 mmhg)
boolean
C1868885 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
Blood Coagulation Disorders
Item
history of coagulopathies
boolean
C0005779 (UMLS CUI [1])
Malignant Neoplasms | Exception Skin carcinoma
Item
history (within the last 5 years) or presence of malignancy, (skin cancers, with the exception of melanoma, may be acceptable)
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])
Substance Use Disorders | Drinks U/day
Item
current or history of drug abuse or alcohol abuse (>2 drinks/day)
boolean
C0038586 (UMLS CUI [1])
C0001967 (UMLS CUI [2,1])
C0456683 (UMLS CUI [2,2])
Glucocorticoids, Systemic | Adrenergic beta-1 Receptor Antagonists | Weight-Loss Agents | Niacin | Fibrates
Item
prior treatment (within last 3 months) with systemic glucocorticoids (>2 weeks), beta-blockers, drugs for weight loss, niacin or fibrates
boolean
C3540777 (UMLS CUI [1])
C0304516 (UMLS CUI [2])
C0376606 (UMLS CUI [3])
C0027996 (UMLS CUI [4])
C1449704 (UMLS CUI [5])
HIV Infection | Hepatitis B | Hepatitis C | Tuberculosis
Item
history of hiv, active hepatitis b or c, or tuberculosis (participant reported)
boolean
C0019693 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019196 (UMLS CUI [3])
C0041296 (UMLS CUI [4])
Tobacco use Number of cigarettes per day
Item
smoke > 5 cigarettes per day
boolean
C0543414 (UMLS CUI [1,1])
C3694146 (UMLS CUI [1,2])