Age
Item
subjects age 18-80
boolean
C0001779 (UMLS CUI [1])
Secondary Progressive Multiple Sclerosis Untreated | Therapy Consistent Secondary Progressive Multiple Sclerosis
Item
secondary progressive ms subjects either untreated or on consistent treatment for six-months prior to enrollment
boolean
C0751965 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0332290 (UMLS CUI [2,2])
C0751965 (UMLS CUI [2,3])
Controls Normal
Item
norman controls
boolean
C0009932 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Pregnancy | Childbearing Potential Contraceptive methods Absent
Item
subjects pregnant or woman of child-bearing age not utilizing effective birth control
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Multiple Sclerosis, Primary Progressive
Item
primary progressive ms subjects
boolean
C0751964 (UMLS CUI [1])
Multiple Sclerosis, Relapsing-Remitting
Item
relapsing remitting ms subjects
boolean
C0751967 (UMLS CUI [1])
Secondary Progressive Multiple Sclerosis Unstable | Therapy change Probably
Item
unstable spms subject for which treatment change within the 24 months is likely
boolean
C0751965 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C3665894 (UMLS CUI [2,1])
C0750492 (UMLS CUI [2,2])
Healthy Control Age Related | Other medical condition
Item
age-healthy controls will be excluded if have any of the following medical conditions:
boolean
C2986479 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0439849 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2])
CNS disorder
Item
any central nervous system disorder
boolean
C0007682 (UMLS CUI [1])
Systemic autoimmune disease
Item
any systemic auto-immune disorder
boolean
C2895206 (UMLS CUI [1])
Pregnancy | Childbearing Potential Contraceptive methods Absent
Item
pregnant or woman of child-bearing age not utilizing effective birth control
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Therapy change
Item
subjects will be withdrawn from the study if treatment is changed during the 24-month study
boolean
C3665894 (UMLS CUI [1])