Squamous cell carcinoma | Oropharyngeal Carcinoma Immunohistochemistry Negative | P16 Staining Immunohistochemistry | Carcinoma of larynx | Hypopharyngeal Carcinoma | Oral Cavity Carcinoma | Nasopharyngeal carcinoma | Paranasal Sinus Cancer
Item
the patient must have squamous cell carcinoma proven by histologic diagnosis; for cancers of the oropharynx, p16 staining by immunohistochemistry must be negative; for cancers of the larynx, hypopharynx, oral cavity, nasopharynx, paranasal sinuses, p16 staining is not required
boolean
C0007137 (UMLS CUI [1])
C2349952 (UMLS CUI [2,1])
C0021044 (UMLS CUI [2,2])
C1513916 (UMLS CUI [2,3])
C2354136 (UMLS CUI [3,1])
C0487602 (UMLS CUI [3,2])
C0021044 (UMLS CUI [3,3])
C0595989 (UMLS CUI [4])
C1368404 (UMLS CUI [5])
C0151546 (UMLS CUI [6])
C2931822 (UMLS CUI [7])
C0854995 (UMLS CUI [8])
Carcinoma TNM clinical staging | Neoplasm Metastasis Burden Limited
Item
the patient must have clinical stage t1-4, n0-3, m0-1, stage ii-ivc carcinoma as per the 7th edition of the american joint committee on cancer (ajcc) staging manual; patients with t1n0m0 or t2n0m0 will be ineligible; patients with metastatic disease with a limited metastatic burden are eligible if obtaining local control is determined by their treating oncologist to be an important therapeutic goal
boolean
C0007097 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C0027627 (UMLS CUI [2,1])
C1449699 (UMLS CUI [2,2])
C0439801 (UMLS CUI [2,3])
Primary tumor Longest Diameter Imaging | Lymph Node Involvement Longest Diameter Imaging
Item
the patient must have imaging documenting a primary tumor, or involved lymph node, >= 2.5 cm in greatest dimension
boolean
C0677930 (UMLS CUI [1,1])
C0552406 (UMLS CUI [1,2])
C0011923 (UMLS CUI [1,3])
C0806692 (UMLS CUI [2,1])
C0552406 (UMLS CUI [2,2])
C0011923 (UMLS CUI [2,3])
PET/CT Required | Exception Medical contraindication
Item
pet/ct is required for all patients, unless contraindicated; this may be acquired prior to study entry or after enrollment prior to sbrt planning
boolean
C1699633 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C1301624 (UMLS CUI [2,2])
Patient Ineligible Cisplatin Chemotherapy
Item
the patient must have a history and physical documented within four weeks of registration and be deemed by a medical oncologist to be ineligible for standard continuous course chemoradiotherapy with cisplatin
boolean
C0030705 (UMLS CUI [1,1])
C1512714 (UMLS CUI [1,2])
C0008838 (UMLS CUI [1,3])
C0392920 (UMLS CUI [1,4])
Karnofsky Performance Status
Item
karnofsky performance status (ps) >= 40
boolean
C0206065 (UMLS CUI [1])
Childbearing Potential Absent | Childbearing Potential Pregnancy test negative | Childbearing Potential Contraceptive methods
Item
female patients cannot be of childbearing age, or if they are, must have a negative pregnancy test prior to enrollment and be willing to use contraceptives during treatment and continue for 6 additional months
boolean
C3831118 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0427780 (UMLS CUI [2,2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
Informed Consent
Item
patients must have the ability to understand and the willingness to sign a written informed consent document
boolean
C0021430 (UMLS CUI [1])
Disease TNM clinical staging
Item
patients with t1n0m0 stage i disease
boolean
C0012634 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Investigational New Drugs
Item
patients who are receiving any other investigational agents
boolean
C0013230 (UMLS CUI [1])
Non-squamous cell Histology
Item
patients with non-squamous cell histology
boolean
C1545484 (UMLS CUI [1,1])
C0344441 (UMLS CUI [1,2])
Life Expectancy
Item
patients with life expectancy < 6 months
boolean
C0023671 (UMLS CUI [1])
Lacking Able to maintain a lying position Duration
Item
patients who cannot lie flat for 20 minutes
boolean
C0332268 (UMLS CUI [1,1])
C4075030 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Radiotherapy to head and neck
Item
patients with prior history of head and neck radiotherapy (> 40 gy) with significant areas of anticipated overlap
boolean
C3888854 (UMLS CUI [1])