age at least 18 Years
Item
Alter mindestens 18 Jahre
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
The patient has histologically or cytologically confirmed, nonsquamous (adenocarcinoma/large cell or other) NSCLC.
Item
The patient has histologically or cytologically confirmed, nonsquamous (adenocarcinoma/large cell or other) NSCLC.
boolean
C0205462 (UMLS CUI 2011AA)
67151002 (SNOMED CT 2011_0131)
C0205471 (UMLS CUI 2011AA)
40413002 (SNOMED CT 2011_0131)
C0750484 (UMLS CUI 2011AA)
C2585890 (UMLS CUI 2011AA)
440173001 (SNOMED CT 2011_0131)
C0152013 (UMLS CUI 2011AA)
254626006 (SNOMED CT 2011_0131)
10025031 (MedDRA 14.1)
C0345958 (UMLS CUI 2011AA)
254629004 (SNOMED CT 2011_0131)
10023774 (MedDRA 14.1)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C0007131 (UMLS CUI 2011AA)
254637007 (SNOMED CT 2011_0131)
10061873 (MedDRA 14.1)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
The patient has Stage IV disease at the time of study entry.
Item
The patient has Stage IV disease at the time of study entry.
boolean
C0441772 (UMLS CUI 2011AA)
258228008 (SNOMED CT 2011_0131)
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
C2348558 (UMLS CUI 2011AA)
Patients with treated brain metastases are eligible if they are clinically stable with regard to neurologic function, off steroids after cranial irradiation (whole brain radiation therapy, focal radiation therapy, and stereotactic radiosurgery) ending at least 2 weeks prior to randomization, or after surgical resection performed at least 28 days prior to randomization. The patient may have no evidence of Grade 1 (or greater) Central Nervous System (CNS) hemorrhage based on pretreatment scans(performed within 21 days before randomization).
Item
Patients with treated brain metastases are eligible if they are clinically stable with regard to neurologic function, off steroids after cranial irradiation (whole brain radiation therapy, focal radiation therapy, and stereotactic radiosurgery) ending at least 2 weeks prior to randomization, or after surgical resection performed at least 28 days prior to randomization. The patient may have no evidence of Grade 1 (or greater) Central Nervous System (CNS) hemorrhage based on pretreatment scans(performed within 21 days before randomization).
boolean
CL415147 (UMLS CUI 2011AA)
C0220650 (UMLS CUI 2011AA)
10006128 (MedDRA 14.1)
C1302261 (UMLS CUI 2011AA)
399223003 (SNOMED CT 2011_0131)
C0750557 (UMLS CUI 2011AA)
C0205360 (UMLS CUI 2011AA)
58158008 (SNOMED CT 2011_0131)
MTHU015276 (LOINC Version 232)
C0027767 (UMLS CUI 2011AA)
18373002 (SNOMED CT 2011_0131)
C1518543 (UMLS CUI 2011AA)
420680007 (SNOMED CT 2011_0131)
C0038317 (UMLS CUI 2011AA)
116566001 (SNOMED CT 2011_0131)
C0079172 (UMLS CUI 2011AA)
C1520143 (UMLS CUI 2011AA)
C0205234 (UMLS CUI 2011AA)
87017008 (SNOMED CT 2011_0131)
C0034619 (UMLS CUI 2011AA)
C0085203 (UMLS CUI 2011AA)
115959002 (SNOMED CT 2011_0131)
10066144 (MedDRA 14.1)
92.30 (ICD-9-CM Version 2011)
C0728940 (UMLS CUI 2011AA)
65801008 (SNOMED CT 2011_0131)
C0332125 (UMLS CUI 2011AA)
41647002 (SNOMED CT 2011_0131)
C1560582 (UMLS CUI 2011AA)
MTHU112377 (CTCAE 1105E)
C1560583 (UMLS CUI 2011AA)
MTHU113168 (CTCAE 1105E)
C1560584 (UMLS CUI 2011AA)
MTHU114179 (CTCAE 1105E)
C1560585 (UMLS CUI 2011AA)
MTHU115195 (CTCAE 1105E)
C1560586 (UMLS CUI 2011AA)
MTHU116122 (CTCAE 1105E)
The patient has measurable or nonmeasurable disease according to Response Evaluation Criteria In Solid Tumors (RECIST) Version 1.1 guidelines.
Item
The patient has measurable or nonmeasurable disease according to Response Evaluation Criteria In Solid Tumors (RECIST) Version 1.1 guidelines.
boolean
C1513040 (UMLS CUI 2011AA)
C1518373 (UMLS CUI 2011AA)
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
C1709926 (UMLS CUI 2011AA)
C0220845 (UMLS CUI 2011AA)
The patient has an Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of 0 or 1.
Item
The patient has an Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of 0 or 1.
boolean
C1828078 (UMLS CUI 2011AA)
425389002 (SNOMED CT 2011_0131)
C1827388 (UMLS CUI 2011AA)
422512005 (SNOMED CT 2011_0131)
If prior adjuvant chemotherapy, the last dose of adjuvant treatment was administered at least 6 months prior to randomization.
Item
If prior adjuvant chemotherapy, the last dose of adjuvant treatment was administered at least 6 months prior to randomization.
boolean
C0750557 (UMLS CUI 2011AA)
C0281265 (UMLS CUI 2011AA)
C1762893 (UMLS CUI 2011AA)
MTHU014073 (LOINC Version 232)
C0677850 (UMLS CUI 2011AA)
10068969 (MedDRA 14.1)
C0439091 (UMLS CUI 2011AA)
276138003 (SNOMED CT 2011_0131)
GE (HL7 V3 2006_05)
C0205452 (UMLS CUI 2011AA)
68244004 (SNOMED CT 2011_0131)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C0034656 (UMLS CUI 2011AA)
The patient has adequate bone marrow reserve, and renal and hepatic function
Item
The patient has adequate bone marrow reserve, and renal and hepatic function
boolean
C0205411 (UMLS CUI 2011AA)
88323005 (SNOMED CT 2011_0131)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
C2347957 (UMLS CUI 2011AA)
C0232804 (UMLS CUI 2011AA)
11953005 (SNOMED CT 2011_0131)
C0232741 (UMLS CUI 2011AA)
79036002 (SNOMED CT 2011_0131)
The patient has fasting serum glucose <= 100 mg/dL, and hemoglobin A1C <= 6%.
Item
The patient has fasting serum glucose <= 100 mg/dL, and hemoglobin A1C <= 6%.
boolean
C0583334 (UMLS CUI 2011AA)
167087006 (SNOMED CT 2011_0131)
C0019018 (UMLS CUI 2011AA)
33601001 (SNOMED CT 2011_0131)
MTHU018890 (LOINC Version 232)
Females with reproductive potential: Must have a negative serum or urine pregnancy test within 7 days prior to the first dose of any study drug.
Item
Females with reproductive potential: Must have a negative serum or urine pregnancy test within 7 days prior to the first dose of any study drug.
boolean
C0015780 (UMLS CUI 2011AA)
248152002 (SNOMED CT 2011_0131)
F (HL7 V3 2006_05)
C0035150 (UMLS CUI 2011AA)
C0237399 (UMLS CUI 2011AA)
C0027552 (UMLS CUI 2011AA)
410525008 (SNOMED CT 2011_0131)
C0430061 (UMLS CUI 2011AA)
166435006 (SNOMED CT 2011_0131)
C0430057 (UMLS CUI 2011AA)
167254001 (SNOMED CT 2011_0131)
10036577 (MedDRA 14.1)
Males and females with reproductive potential: Must agree to use medically approved contraceptive precautions during the study and for 6 months following the last dose of any study drug.
Item
Males and females with reproductive potential: Must agree to use medically approved contraceptive precautions during the study and for 6 months following the last dose of any study drug.
boolean
C0024554 (UMLS CUI 2011AA)
248153007 (SNOMED CT 2011_0131)
M (HL7 V3 2006_05)
C0015780 (UMLS CUI 2011AA)
248152002 (SNOMED CT 2011_0131)
F (HL7 V3 2006_05)
C0035150 (UMLS CUI 2011AA)
C0237399 (UMLS CUI 2011AA)
C0680240 (UMLS CUI 2011AA)
C0700589 (UMLS CUI 2011AA)
146680009 (SNOMED CT 2011_0131)
10010808 (MedDRA 14.1)
The patient has the ability to understand and the willingness to sign a written informed consent form.
Item
The patient has the ability to understand and the willingness to sign a written informed consent form.
boolean
C1273101 (UMLS CUI 2011AA)
395659009 (SNOMED CT 2011_0131)
C0600109 (UMLS CUI 2011AA)
225466006 (SNOMED CT 2011_0131)
C2348583 (UMLS CUI 2011AA)
Previous radiation therapy is allowed to < 25% of the bone marrow, but should have been limited and must not have included whole pelvis radiation.
Item
Previous radiation therapy is allowed to < 25% of the bone marrow, but should have been limited and must not have included whole pelvis radiation.
boolean
CL414551 (UMLS CUI 2011AA)
C1524004 (UMLS CUI 2011AA)
C0439092 (UMLS CUI 2011AA)
276139006 (SNOMED CT 2011_0131)
LT (HL7 V3 2006_05)
C2825406 (UMLS CUI 2011AA)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
CL411789 (UMLS CUI 2011AA)
C0444667 (UMLS CUI 2011AA)
260232004, 255503000 (SNOMED CT 2011_0131)
C0030797 (UMLS CUI 2011AA)
12921003 (SNOMED CT 2011_0131)
MTHU001438 (LOINC Version 232)
The patient has archived tumor tissue available for analysis (can be either primary tumor or metastases).
Item
The patient has archived tumor tissue available for analysis (can be either primary tumor or metastases).
boolean
C0003738 (UMLS CUI 2011AA)
C0475358 (UMLS CUI 2011AA)
258435002 (SNOMED CT 2011_0131)
C0470187 (UMLS CUI 2011AA)
103328004 (SNOMED CT 2011_0131)
C0002778 (UMLS CUI 2011AA)
272389005 (SNOMED CT 2011_0131)
The patient has an estimated life expectancy of at least 12 weeks.
Item
The patient has an estimated life expectancy of at least 12 weeks.
boolean
C0750572 (UMLS CUI 2011AA)
414135002 (SNOMED CT 2011_0131)
C0023671 (UMLS CUI 2011AA)
LP75025-4 (LOINC Version 232)
C0439091 (UMLS CUI 2011AA)
276138003 (SNOMED CT 2011_0131)
GE (HL7 V3 2006_05)
C0205458 (UMLS CUI 2011AA)
82809009 (SNOMED CT 2011_0131)
C0439230 (UMLS CUI 2011AA)
258705008 (SNOMED CT 2011_0131)
WK (HL7 V3 2006_05)
Are currently enrolled in, or discontinued within the last 30 days from, a clinical trial involving an investigational drug or device or off-label use of a drug or device, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study.
Item
Are currently enrolled in, or discontinued within the last 30 days from, a clinical trial involving an investigational drug or device or off-label use of a drug or device, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study.
boolean
C1516879 (UMLS CUI 2011AA)
C0008976 (UMLS CUI 2011AA)
110465008 (SNOMED CT 2011_0131)
C0013230 (UMLS CUI 2011AA)
C2346570 (UMLS CUI 2011AA)
C1096117 (UMLS CUI 2011AA)
10053762 (MedDRA 14.1)
C0013227 (UMLS CUI 2011AA)
C0699733 (UMLS CUI 2011AA)
49062001 (SNOMED CT 2011_0131)
MTHU020022 (LOINC Version 232)
Patients who have squamous histology.
Item
Patients who have squamous histology.
boolean
C1182670 (UMLS CUI 2011AA)
C0344441 (UMLS CUI 2011AA)
10062005 (MedDRA 14.1)
MTHU010496 (LOINC Version 232)
The patient's tumor fully or partially contains Small Cell Lung Cancer (SCLC).
Item
The patient's tumor fully or partially contains Small Cell Lung Cancer (SCLC).
boolean
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0332256 (UMLS CUI 2011AA)
42504009 (SNOMED CT 2011_0131)
C0149925 (UMLS CUI 2011AA)
254632001 (SNOMED CT 2011_0131)
10041071 (MedDRA 14.1)
The patient has leptomeningeal disease.
Item
Leptomeningeal disease
boolean
CL428853 (UMLS CUI 2011AA)
10070973 (MedDRA 14.1)
The patient is currently or has previously received chemotherapy for advanced (Stage IV) NSCLC. Patients who have received adjuvant chemotherapy are eligible if the last administration of the prior adjuvant regimen occurred at least 6 months prior to randomization
Item
The patient is currently or has previously received chemotherapy for advanced (Stage IV) NSCLC. Patients who have received adjuvant chemotherapy are eligible if the last administration of the prior adjuvant regimen occurred at least 6 months prior to randomization
boolean
C0392920 (UMLS CUI 2011AA)
150415003 (SNOMED CT 2011_0131)
C0278987 (UMLS CUI 2011AA)
10025055 (MedDRA 14.1)
C0085533 (UMLS CUI 2011AA)
C1548635 (UMLS CUI 2011AA)
ELG (HL7 V3 2006_05)
C0750557 (UMLS CUI 2011AA)
C0205452 (UMLS CUI 2011AA)
68244004 (SNOMED CT 2011_0131)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C0034656 (UMLS CUI 2011AA)
The patient has a history of treatment with other agents targeting the Insulin-like or Epidermal Growth factor receptors.
Item
The patient has a history of treatment with other agents targeting the Insulin-like or Epidermal Growth factor receptors.
boolean
CL421546 (UMLS CUI 2011AA)
392521001 (SNOMED CT 2011_0131)
C0039798 (UMLS CUI 2011AA)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C1254351 (UMLS CUI 2011AA)
C1521840 (UMLS CUI 2011AA)
C0140079 (UMLS CUI 2011AA)
C0034802 (UMLS CUI 2011AA)
86960007 (SNOMED CT 2011_0131)
MTHU004296 (LOINC Version 232)
Patients who have received prior Pemetrexed treatment.
Item
Patients who have received prior Pemetrexed treatment.
boolean
C1514463 (UMLS CUI 2011AA)
C0210657 (UMLS CUI 2011AA)
411089001 (SNOMED CT 2011_0131)
The patient has a known allergy/history of hypersensitivity reaction to any of the treatment components.
Item
The patient has a known allergy/history of hypersensitivity reaction to any of the treatment components.
boolean
C0020517 (UMLS CUI 2011AA)
257550005 (SNOMED CT 2011_0131)
T78.40 (ICD-10-CM Version 2010)
C0489531 (UMLS CUI 2011AA)
MTHU001065 (LOINC Version 232)
CL407060 (UMLS CUI 2011AA)
C0039798 (UMLS CUI 2011AA)
C1705248 (UMLS CUI 2011AA)
The patient has diabetes mellitus.
Item
Diabetes mellitus
boolean
C0011849 (UMLS CUI 2011AA)
191044006 (SNOMED CT 2011_0131)
The patient has an uncontrolled intercurrent illness including, but not limited to, ongoing or active infection requiring parenteral antibiotics, symptomatic congestive heart failure, uncontrolled hypertension, clinically significant cardiac arrhythmia,or psychiatric/social situations that would limit compliance with study requirements.
Item
The patient has an uncontrolled intercurrent illness including, but not limited to, ongoing or active infection requiring parenteral antibiotics, symptomatic congestive heart failure, uncontrolled hypertension, clinically significant cardiac arrhythmia,or psychiatric/social situations that would limit compliance with study requirements.
boolean
C0205318 (UMLS CUI 2011AA)
19032002 (SNOMED CT 2011_0131)
C0277557 (UMLS CUI 2011AA)
88472004 (SNOMED CT 2011_0131)
C0021311 (UMLS CUI 2011AA)
257551009 (SNOMED CT 2011_0131)
10021789 (MedDRA 14.1)
C1514873 (UMLS CUI 2011AA)
C1518896 (UMLS CUI 2011AA)
C0003232 (UMLS CUI 2011AA)
255631004 (SNOMED CT 2011_0131)
C0018802 (UMLS CUI 2011AA)
42343007 (SNOMED CT 2011_0131)
10007559 (MedDRA 14.1)
MTHU020787 (LOINC Version 232)
I50.9 (ICD-10-CM Version 2010)
428.0 (ICD-9-CM Version 2011)
C1868885 (UMLS CUI 2011AA)
10066860 (MedDRA 14.1)
C0003811 (UMLS CUI 2011AA)
44808001 (SNOMED CT 2011_0131)
10003119 (MedDRA 14.1)
427.9 (ICD-9-CM Version 2011)
C0278060 (UMLS CUI 2011AA)
36456004 (SNOMED CT 2011_0131)
MTHU001424 (LOINC Version 232)
MTHU117157 (CTCAE 1105E)
C0851364 (UMLS CUI 2011AA)
10041244 (MedDRA 14.1)
C0439801 (UMLS CUI 2011AA)
255469002 (SNOMED CT 2011_0131)
C0525058 (UMLS CUI 2011AA)
The patient has an ongoing or active infection requiring parenteral antibiotic, antifungal, or antiviral therapy.
Item
The patient has an ongoing or active infection requiring parenteral antibiotic, antifungal, or antiviral therapy.
boolean
C0021311 (UMLS CUI 2011AA)
257551009 (SNOMED CT 2011_0131)
10021789 (MedDRA 14.1)
C1514873 (UMLS CUI 2011AA)
C1518896 (UMLS CUI 2011AA)
C0003232 (UMLS CUI 2011AA)
255631004 (SNOMED CT 2011_0131)
C0003308 (UMLS CUI 2011AA)
373219008 (SNOMED CT 2011_0131)
C2363964 (UMLS CUI 2011AA)
10068724 (MedDRA 14.1)
The patient has undergone major surgery within 28 days prior to randomization.
Item
The patient has undergone major surgery within 28 days prior to randomization.
boolean
C0679637 (UMLS CUI 2011AA)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C0034656 (UMLS CUI 2011AA)
The patient has received a prior autologous or allogeneic organ or tissue transplantation.
Item
The patient has received a prior autologous or allogeneic organ or tissue transplantation.
boolean
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C0439859 (UMLS CUI 2011AA)
255379001 (SNOMED CT 2011_0131)
C1515895 (UMLS CUI 2011AA)
C0029216 (UMLS CUI 2011AA)
10061890 (MedDRA 14.1)
MTHU000173 (LOINC Version 232)
C0080232 (UMLS CUI 2011AA)
The patient is pregnant or lactating.
Item
The patient is pregnant or lactating.
boolean
C0549206 (UMLS CUI 2011AA)
10036586 (MedDRA 14.1)
C2828358 (UMLS CUI 2011AA)
The patient has a history of another primary cancer, with the exception of the following: curatively resected nonmelanomatous skin cancer, curatively treated carcinoma in situ, or other primary solid tumor treated with curative intent and no known active disease present and no treatment administered during the last 5 years.
Item
The patient has a history of another primary cancer, with the exception of the following: curatively resected nonmelanomatous skin cancer, curatively treated carcinoma in situ, or other primary solid tumor treated with curative intent and no known active disease present and no treatment administered during the last 5 years.
boolean
CL421546 (UMLS CUI 2011AA)
392521001 (SNOMED CT 2011_0131)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C1306459 (UMLS CUI 2011AA)
372087000 (SNOMED CT 2011_0131)
C1554961 (UMLS CUI 2011AA)
E (HL7 V3 2006_05)
C1880198 (UMLS CUI 2011AA)
C1521996 (UMLS CUI 2011AA)
C0699893 (UMLS CUI 2011AA)
10040810 (MedDRA 14.1)
CL415147 (UMLS CUI 2011AA)
C0007099 (UMLS CUI 2011AA)
109355002 (SNOMED CT 2011_0131)
10061450 (MedDRA 14.1)
D09.9 (ICD-10-CM Version 2010)
234.9 (ICD-9-CM Version 2011)
CL414904 (UMLS CUI 2011AA)
C0280100 (UMLS CUI 2011AA)
10065252 (MedDRA 14.1)
The patient has superior vena cava syndrome contraindicating hydration.
Item
The patient has superior vena cava syndrome contraindicating hydration.
boolean
C0038833 (UMLS CUI 2011AA)
63363004 (SNOMED CT 2011_0131)
10042569 (MedDRA 14.1)
E13819 (CTCAE 1105E)
C1444657 (UMLS CUI 2011AA)
410536001 (SNOMED CT 2011_0131)
CL034943 (UMLS CUI 2011AA)
The patient has current clinically-relevant coronary artery disease (New York Heart Association III or IV) or uncontrolled congestive heart failure.
Item
The patient has current clinically-relevant coronary artery disease (New York Heart Association III or IV) or uncontrolled congestive heart failure.
boolean
C0010068 (UMLS CUI 2011AA)
53741008 (SNOMED CT 2011_0131)
10068617 (MedDRA 14.1)
C1319795 (UMLS CUI 2011AA)
420913000 (SNOMED CT 2011_0131)
10064081 (MedDRA 14.1)
C1319796 (UMLS CUI 2011AA)
422293003 (SNOMED CT 2011_0131)
10064082 (MedDRA 14.1)
C0205318 (UMLS CUI 2011AA)
19032002 (SNOMED CT 2011_0131)
C0018802 (UMLS CUI 2011AA)
42343007 (SNOMED CT 2011_0131)
10007559 (MedDRA 14.1)
MTHU020787 (LOINC Version 232)
I50.9 (ICD-10-CM Version 2010)
428.0 (ICD-9-CM Version 2011)
The patient has any Grade 2 (or greater) peripheral neuropathy.
Item
The patient has any Grade 2 (or greater) peripheral neuropathy.
boolean
C0031117 (UMLS CUI 2011AA)
10029331 (MedDRA 14.1)
G64 (ICD-10-CM Version 2010)
350-359.99 (ICD-9-CM Version 2011)
C0441800 (UMLS CUI 2011AA)
258349007 (SNOMED CT 2011_0131)
MTHU003112 (LOINC Version 232)
The patient has clinically significant third-space fluid collections, for example, ascites or pleural effusions that cannot be controlled by drainage or other procedures prior to study entry.
Item
The patient has clinically significant third-space fluid collections, for example, ascites or pleural effusions that cannot be controlled by drainage or other procedures prior to study entry.
boolean
C0205437 (UMLS CUI 2011AA)
70905002 (SNOMED CT 2011_0131)
C0229984 (UMLS CUI 2011AA)
2969000 (SNOMED CT 2011_0131)
CL427986 (UMLS CUI 2011AA)
C1516698 (UMLS CUI 2011AA)
C0003962 (UMLS CUI 2011AA)
389026000 (SNOMED CT 2011_0131)
10003445 (MedDRA 14.1)
R18 (ICD-10-CM Version 2010)
789.5 (ICD-9-CM Version 2011)
E10502 (CTCAE 1105E)
C0032227 (UMLS CUI 2011AA)
60046008 (SNOMED CT 2011_0131)
10035598 (MedDRA 14.1)
J90 (ICD-10-CM Version 2010)
511.9 (ICD-9-CM Version 2011)
E13486 (CTCAE 1105E)
C1272705 (UMLS CUI 2011AA)
385671000 (SNOMED CT 2011_0131)
C0013103 (UMLS CUI 2011AA)
122462000 (SNOMED CT 2011_0131)
The patient is unable to interrupt aspirin or other nonsteroidal anti-inflammatory agents, other than an aspirin dose <= 1.3 grams per day, for a 5-day period (8-day period for long-acting agents, such as piroxicam).
Item
The patient is unable to interrupt aspirin or other nonsteroidal anti-inflammatory agents, other than an aspirin dose <= 1.3 grams per day, for a 5-day period (8-day period for long-acting agents, such as piroxicam).
boolean
C1299582 (UMLS CUI 2011AA)
371151008 (SNOMED CT 2011_0131)
C1512900 (UMLS CUI 2011AA)
C0004057 (UMLS CUI 2011AA)
7947003 (SNOMED CT 2011_0131)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C0003211 (UMLS CUI 2011AA)
16403005, 372665008 (SNOMED CT 2011_0131)
C0031990 (UMLS CUI 2011AA)
27754002 (SNOMED CT 2011_0131)
MTHU001848 (LOINC Version 232)
The patient is unwilling or unable to take premedications (folic acid, vitamin B12, or corticosteroids) required by the pemetrexed label.
Item
The patient is unwilling or unable to take premedications (folic acid, vitamin B12, or corticosteroids) required by the pemetrexed label.
boolean
C1299582 (UMLS CUI 2011AA)
371151008 (SNOMED CT 2011_0131)
C0558080 (UMLS CUI 2011AA)
225465005 (SNOMED CT 2011_0131)
C1512806 (UMLS CUI 2011AA)
C0033045 (UMLS CUI 2011AA)
10036500 (MedDRA 14.1)
C0016410 (UMLS CUI 2011AA)
6247001 (SNOMED CT 2011_0131)
C0042845 (UMLS CUI 2011AA)
81064004 (SNOMED CT 2011_0131)
C0001617 (UMLS CUI 2011AA)
79440004 (SNOMED CT 2011_0131)
The patient has received a recent (within 30 days of enrollment) or is receiving concurrent yellow fever vaccination.
Item
The patient has received a recent (within 30 days of enrollment) or is receiving concurrent yellow fever vaccination.
boolean
C1514756 (UMLS CUI 2011AA)
C0199823 (UMLS CUI 2011AA)
67308009 (SNOMED CT 2011_0131)
10069614 (MedDRA 14.1)
99.43 (ICD-9-CM Version 2011)